Therapeutic Area Head, General Medicine in London

Overview Updated: January 21, 2026Location: GBR-London-HybridJob ID: 25105080Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Every day we perform better because of how we work together, as one team, each the best at what we do. We bring a wide range of talented experts together across a wide range of business-critical services that support our business. Every role within Corporate is vital to furthering our vision of Shortening the Distance from Lab to Life. Discover what our 29,000 employees, across 110 countries already know.WORK HERE MATTERS EVERYWHEREWhy Syneos HealthWe are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.We are continuously building the company we all want to work for and our customers want to work with. When we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we\’re able to create a place where everyone feels like they belong.Position Therapeutic Area Head – General MedicineThe Therapeutic Area Head – General Medicine provides strategic, scientific, and operational leadership across a diverse global portfolio that includes Infectious Disease, Vaccines, Respiratory, Cell & Gene Therapy (CGT), and select Medical Device & Diagnostics (MD&D) programs. Following the strategic carve-out of Cardiometabolic and Intensive Care, this role focuses on the therapeutic areas with the strongest right to win and the largest opportunities to scale.This executive is responsible for advancing clinical delivery excellence, shaping therapeutic strategy, modernizing capabilities, and driving high-value growth in line with the organization\’s 2026 and long-range plan goals. As a senior member of the Global Project Management Leadership Team, the Therapeutic Area Head serves as a scientific authority, operational strategist, and partner to clients, industry stakeholders, and internal teams.Key Responsibilities Strategic LeadershipDevelop and execute the strategic vision for General Medicine delivery, ensuring alignment with corporate priorities, therapeutic growth strategies, and evolving market needs.Lead the transformation of General Medicine go-to-market strategy, including modernization of TCOE-based collateral, global presence, and orchestrated conference activities.Anticipate emerging scientific, regulatory, and competitive trends within ID, vaccines, respiratory, CGT, and MD&D to position Syneos Health as the preferred partner in these segments.Partner with senior executives across the enterprise to ensure cohesive, scalable operational models that support rapid growth and portfolio diversification.Scientific Authority & External InfluenceMaintain deep scientific fluency across infectious disease, immunology, respiratory medicine, vaccines, advanced therapies, and MD&D.Serve as a recognized scientific and strategic advisor to senior-level clients, regulatory bodies, and external partners.Represent the organization in global scientific forums and industry associations to strengthen visibility, credibility, and thought-leadership.Shape client strategies by integrating scientific evidence, commercial insights, and global development considerations.Provide executive oversight for all General Medicine projects across phases I–IV, ensuring operational excellence, forecasting accuracy, proactive risk mitigation, and client satisfaction.Guide portfolio prioritization and resource alignment to support growth trajectories in vaccines (EU/APAC), global ID programs, respiratory innovation, CGT capability expansion, and MD&D partnerships.Establish governance structures to monitor delivery performance, escalate issues, and drive continuous improvement across global teams.Collaborate with operational and scientific leaders to modernize delivery capabilities, including analytics, AI-enabled risk management, and evidence-based decision frameworks.Executive Client Management & Business DevelopmentServe as senior executive liaison for key strategic General Medicine clients.Expand growth opportunities by partnering with BD, Medical, and operational leaders to enhance cross-portfolio visibility and strengthen client value propositions.Support high-stakes engagements—including bid defenses, RFIs, and partnership negotiations, assuring alignment with Syneos Health\’s strategic objectives and performance commitments.Build and sustain long-term partnerships that reinforce Syneos Health\’s differentiated scientific and operational capabilities.Financial & Operational LeadershipMaintain full accountability for the financial performance of the General Medicine portfolio, including forecasting, profitability, and resource optimization.Strengthen portfolio economics by driving operational efficiency, predictability, and data-driven decision making.Partner with Finance and Operations to ensure scalable business models that support global growth ambitions through 2028 and beyond.Organizational Leadership & Talent DevelopmentLead and mentor a global leadership team (VP and below), fostering a culture of empowerment, collaboration, accountability, and high performance.Build talent and succession pipelines for scientific, operational, and executive leadership roles within General Medicine.Promote an inclusive culture that values diverse expertise and drives innovation across therapeutic and geographic lines.Quality, Compliance & Continuous ImprovementEnsure compliance with ICH/GCP, regulatory standards, and internal quality systems across the General Medicine portfolio.Collaborate with Quality leadership to support inspection readiness and ensure consistent quality across global operations.Lead transformation initiatives aimed at modernizing General Medicine capabilities—such as revamping CGT consortia, strengthening MD&D central capabilities, and optimizing TCOE infrastructure.Drive continuous improvement and process optimization that enhance delivery scalability, client satisfaction, and operational resilience.Qualifications Advanced degree (MS, PharmD, MD, PhD, or equivalent) in Life Sciences, Medicine, Pharmacy, or a related scientific discipline required.Minimum of 15+ years of experience in clinical research, project management, or clinical operations within CRO, pharmaceutical, or biotechnology settings.Proven leadership experience overseeing complex clinical development programs in infectious disease, vaccines, respiratory, or advanced therapies; MD&D experience preferred.Demonstrated ability to lead large, global portfolios and multi-layered leadership teams.Strong business acumen with experience in forecasting, financial management, and therapeutic growth strategy.Expert understanding of drug development, GCP/ICH guidelines, global regulatory expectations, and evolving scientific landscapes.Exceptional executive presence with the ability to influence C-suite stakeholders, clients, and internal leaders.Track record of driving innovation, transformation, and delivery modernization.Ability to travel as required (approximately 30–35%).BenefitsThe benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Some benefits vary by location and regulatory requirements.Salary Range$245,600.00 – $454,300.00The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on factors such as the candidate\’s qualifications, skills, and proficiency for the role.Get to know Syneos Health Discover what our 29,000 employees already know: work here matters everywhere. We work hard, and smart, all in the name of getting therapies to patients. Learn more about Syneos Health at http://www.syneoshealth.comAdditional InformationTasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company may assign other tasks, duties, and responsibilities. Equivalent experience, skills, and/or education will be considered. The Company will determine what constitutes equivalent qualifications. This description does not create a contract. Some required skills/experiences may be described briefly. This content complies with applicable laws, including the EU Equality Directive and the Americans with Disabilities Act.Equal Opportunity Syneos Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, marital status, ethnicity, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability or any other legally protected status. If you require reasonable accommodation for the application process, contact jobs@syneoshealth.com.

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