Sr Biostatistician-Sr Data Scientist/Analyst (US and UK Only) in London

Must be located in the United States or UK with no sponsorship needs to be considered for this position.

Lead development of analysis specifications, develop programs, and conduct analyses while providing technical guidance for Real World Data (RWD) research. Ensure quality standards and methodological rigor across projects through development of patient cohorts and validation of key variables.

• Leadership of RWD analysis strategy and execution
• Lead development of technical specifications and study methodology
• Statistical programming proficiency (R, SAS, SQL, Python)
• Oversight of quality control processes
• Cross-functional team collaboration
• Management of project timelines and deliverables
• Development of best practices and standards
• Demonstrated ability to communicate complex analyses to non-technical stakeholders

• Proficiency in SAS or R & SQL is a must, expectation to be programming independently, creating packages, taking requirements, writing specifications, work with complex data structures and study design.
• Experience in more complex programming, such as propensity score analysis, lines of therapy, Sankey diagram, machine learning
• Experience with complex statistical programming, such as propensity score matching
• Experience applying machine learning methods (such as LASSO, DT, RF, and XGBoost) with RWD
• Experience with OHDSI or DARWIN tool sets in R

• Understanding of epidemiology / outcomes research, experience with study design and execution, Biomarker/genomic data sources
• Experience with healthcare databases: Claims (examples include Optum, MarketScan, Pharmetrics+, HealthVerity, CPRD)
• Electronic Health Records (examples include IQVIA, Flatiron, Concert AI, TriNetX)
• Experience with OMOP CDM or similar common data model framework
• Knowledge of US/international data sources

• Experience with psychometric validation

• Statistical analysis plan development
• Protocol / manuscript development
• Study design and execution
• Cross-functional team collaboration
• Being able to track and update work in a software (Jira or ADO)

• Master's degree in Biostatistics, Epidemiology, Data Science, Bioinformatics, or related field with 5-8 years of relevant post-graduation experience or PhD with 3+ years post-graduation experience
• Advanced expertise in statistical programming and observational research methods
• Comprehensive experience with healthcare data sources and analysis
• Proven ability to lead projects autonomously in a matrix environment
• Track record of managing priorities and performance targets

• Oncology Specific: Experience in oncology observational studies, experience in Flatiron and ConcertAI, understanding of programming logic in lines of therapy
• Molecular Epi Specific: Cloud-based SQL is desirable
• Experience with Clinico-genomic multi-modal data (e.g. Tempus AI) or population biobank data (UK biobank)
• Experience and comfort to multitask and work in a matrix environment
• Tableau or Power BI or other graphics tool is a plus
• HEOR Specific: SAS/SQL required, additional experience with R beneficial
• Experience with health economics and outcomes research (HEOR) methodologies, including cost analysis, burden of illness studies, and comparative effectiveness research

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognise our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, health benefits to include medical, dental and vision, company match 401k, eligibility to participate in Employee Stock Purchase Plan, eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.