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- Tasks: Lead innovative drug discovery projects and mentor a talented team in In Vivo Pharmacology.
- Company: Join Sygnature Discovery, a leading drug discovery organisation with a collaborative spirit.
- Benefits: Enjoy 25 days annual leave, enhanced family policies, and an Employee Assistance Programme.
- Why this job: Make a real impact in metabolic disease research while advancing your career in a dynamic environment.
- Qualifications: PhD or significant industry experience in drug discovery, especially in metabolic diseases.
- Other info: Fast-paced team atmosphere with opportunities for professional growth and development.
The predicted salary is between 48000 - 72000 ÂŁ per year.
Sygnature Discovery is a world‑leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations. Since 2004, Sygnature Discovery has delivered over 56 novel pre‑clinical and 35 clinical compounds, with its scientists named on over 225 patents. Therapeutic areas of expertise include oncology, inflammation and immunology, neuroscience, metabolic diseases, infectious diseases, and more.
We’re looking for an experienced Principal Scientist to join our In Vivo Pharmacology team in Nottingham. This is a fully onsite role based in the heart of Nottingham’s city centre. You will use your strong experience and expertise in drug discovery and In Vivo Pharmacology to play a significant role in operational and leadership responsibilities across the department, as well as championing, leading, and driving progression of the science in the department.
Role Responsibilities
- Act as a Project Lead for research projects, responsible for coordinating the delivery of high‑quality science. This role can require lab presence but will have mostly other significant non‑lab‑based roles and responsibilities.
- Provide scientific guidance and/or mentoring to project team members.
- Line manager duties may also be part of the role.
- Collaborate successfully internally and with clients to design and drive complex drug discovery projects.
- Use excellent problem‑solving skills to make informed decisions and deliver innovative solutions to complex scientific and technical challenges.
- Efficiently negotiate with internal and external stakeholders.
- This role may also involve acting as the Project Licence Holder, ensuring regulatory compliance across relevant permits, and providing oversight to multiple team members.
Skills & Qualifications
- PhD in relevant discipline, with drug discovery experience in industry and/or other relevant Postdoctoral activities. Alternatively, BSc/MSc in relevant discipline with significant drug discovery experience in industry is also suitable.
- This role requires strong technical expertise and a deep understanding of metabolic diseases (obesity, diabetes, cardiometabolic diseases) with proven experience in applying in vivo pharmacological research methods to study these conditions.
- Expert knowledge in the end‑to‑end drug discovery pathway and of current therapeutic landscape is advantageous.
- Good understanding of Home Office legislation governing in vivo research and direct experience in the experimental design and oversight of in vivo studies is advantageous.
- Significant drug discovery experience gained from an industrial environment.
- Proven technical knowledge of in vivo models of obesity (such as the DIO model) and/or of metabolic complications.
- Proven ability to work effectively in a fast‑paced team environment.
- Excellent organisational and data management skills and a proven ability to work across several projects concomitantly.
25 days annual leave (plus bank holidays) Employee Assistance Programme Enhanced Family Friendly Policies
Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.
Seniority level: Mid‑Senior level Employment type: Part‑time Job function: Science Industries: Biotechnology Research and Research Services
Senior Principal Scientist - Metabolic Diseases/In Vivo Pharmacology in Nottingham employer: Sygnature Discovery
Contact Detail:
Sygnature Discovery Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Principal Scientist - Metabolic Diseases/In Vivo Pharmacology in Nottingham
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, seminars, or even local meet-ups. We all know that sometimes it’s not just what you know, but who you know that can land you that dream job.
✨Show Off Your Skills
When you get the chance to chat with potential employers, don’t hold back! Share your experiences and how your expertise in metabolic diseases and in vivo pharmacology can make a difference. We want to see your passion shine through!
✨Prepare for the Interview
Do your homework on the company and the role. Understand their projects and how you can contribute. We suggest practising common interview questions and preparing some insightful questions of your own to show you’re genuinely interested.
✨Apply Through Our Website
Don’t forget to apply directly through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who take the initiative to reach out directly.
We think you need these skills to ace Senior Principal Scientist - Metabolic Diseases/In Vivo Pharmacology in Nottingham
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Senior Principal Scientist. Highlight your experience in drug discovery and in vivo pharmacology, especially related to metabolic diseases. We want to see how your background aligns with what we're looking for!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about this role and how your skills can contribute to our team at Sygnature Discovery. Keep it engaging and relevant to the job description.
Showcase Your Problem-Solving Skills: In your application, don’t forget to mention specific examples where you've tackled complex scientific challenges. We love seeing how you approach problems and come up with innovative solutions, so make sure to highlight those experiences!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets to us quickly and efficiently. Plus, it shows you're keen on joining our team at Sygnature Discovery!
How to prepare for a job interview at Sygnature Discovery
✨Know Your Science
Make sure you brush up on your knowledge of metabolic diseases and in vivo pharmacology. Be ready to discuss specific research methods you've used and how they relate to the role. This will show that you’re not just familiar with the theory but have practical experience too.
✨Showcase Your Leadership Skills
As a Senior Principal Scientist, you'll be expected to lead projects and mentor others. Prepare examples of how you've successfully led teams or projects in the past. Highlight your problem-solving skills and how you've navigated challenges in drug discovery.
✨Understand the Company’s Work
Familiarise yourself with Sygnature Discovery's recent projects and therapeutic areas. Being able to reference their work during the interview will demonstrate your genuine interest in the company and its mission, making you stand out as a candidate.
✨Prepare for Regulatory Questions
Since the role involves compliance with Home Office legislation, be prepared to discuss your understanding of these regulations. Think about how you've ensured compliance in previous roles and be ready to share specific examples.
