At a Glance
- Tasks: Lead innovative in vivo studies in kidney disease and metabolic disorders.
- Company: Join a global team of 700+ scientists at Sygnature Discovery.
- Benefits: Enjoy 25 days leave, private medical insurance, and enhanced family policies.
- Other info: Dynamic environment with opportunities for mentorship and career growth.
- Why this job: Make a real impact on drug discovery and help change lives.
- Qualifications: PhD or relevant experience in drug discovery and in vivo pharmacology.
The predicted salary is between 60000 - 80000 £ per year.
At Sygnature Discovery, we create exceptional scientific outcomes for our customers, who bring life-changing medicines to patients, and for our people, who help make this possible. We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment. Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 200+ patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges.
About the role
We are seeking a highly motivated Associate Principal Scientist to join our In Vivo Pharmacology team in Nottingham. This is an exciting opportunity to play a key role in client-sponsored drug discovery programmes within a dynamic, fast-paced preclinical CRO environment. Working at the forefront of translational science, you will bring your expertise in kidney disease, inflammation and/or metabolic disorders to design, lead and deliver high-quality in vivo studies, contributing directly to the advancement of innovative therapeutics. Please note that this is a full-time onsite position.
Role Responsibilities
- Lead the design, execution and interpretation of in vivo pharmacology studies within kidney, inflammation and/or metabolic disease programmes.
- Act as Project Lead, coordinating multidisciplinary teams to deliver high-quality, timely outcomes for client projects.
- Provide scientific leadership and technical expertise, guiding experimental strategy and solving complex research challenges.
- Drive innovation, implementing novel experimental approaches and technologies to enhance project success and improve scientific capabilities and workflows within the department.
- Collaborate closely with internal teams and external clients, contributing to study design, data interpretation and scientific discussions.
- Support and mentor team members; line management responsibilities may form part of this role.
Skills & Qualifications
- PhD in a relevant discipline with industry or postdoctoral drug discovery experience or BSc/MSc with substantial industry experience in drug discovery.
- Strong expertise in kidney disease, inflammation and/or metabolic disorders.
- Proven experience applying in vivo pharmacology models in drug discovery; expertise in relevant ex vivo assays is highly desirable.
- Experience with end-to-end drug discovery workflows and industrial drug discovery is advantageous.
- Strong understanding of UK regulations governing in vivo research.
- Demonstrated experience in study design, oversight and data interpretation.
- Strong organisational and project management capabilities, with the ability to manage multiple projects simultaneously.
- Effective communicator with proven ability to collaborate across teams and with clients.
Benefits
- 25 days annual leave (plus bank holidays)
- Private Medical Insurance
- Life Insurance
- Employee Assistance Programme
- Enhanced Family Friendly Policies
- Sygnature Group Pension Scheme
- 1 paid volunteer day per year
Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.
Associate Principal Scientist (In Vivo Pharmacology) - Kidney Disease/Inflammation/Metabolic Disease in Nottingham employer: Sygnature Discovery
At Sygnature Discovery, we pride ourselves on fostering a collaborative and innovative work culture that empowers our scientists to make a real impact in drug discovery. Located in Nottingham, our team enjoys a supportive environment with ample opportunities for professional growth, competitive benefits including private medical insurance and enhanced family-friendly policies, and the chance to work on groundbreaking projects that advance life-changing medicines. Join us and be part of a dedicated team where your expertise in kidney disease, inflammation, and metabolic disorders will directly contribute to transformative therapeutic advancements.
StudySmarter Expert Advice🤫
We think this is how you could land Associate Principal Scientist (In Vivo Pharmacology) - Kidney Disease/Inflammation/Metabolic Disease in Nottingham
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
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We think you need these skills to ace Associate Principal Scientist (In Vivo Pharmacology) - Kidney Disease/Inflammation/Metabolic Disease in Nottingham
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Sygnature Discovery that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Sygnature Discovery.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Sygnature Discovery does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Sygnature Discovery
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Sygnature Discovery. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Sygnature Discovery's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Sygnature Discovery. This shows your passion for the industry!
