At a Glance
- Tasks: Join our Protein Science team to engineer and purify proteins for groundbreaking drug discovery.
- Company: Sygnature Discovery, a global leader in scientific outcomes with a collaborative culture.
- Benefits: Enjoy 25 days leave, private medical insurance, life insurance, and enhanced family policies.
- Other info: Dynamic environment with diverse projects and excellent career growth opportunities.
- Why this job: Make a real impact in medicine while working with cutting-edge technologies and talented scientists.
- Qualifications: BSc/MSc or PhD in Biochemistry; experience in protein work is a plus.
The predicted salary is between 30000 - 40000 £ per year.
About Sygnature Discovery: At Sygnature Discovery, we create exceptional scientific outcomes for our customers, who bring life-changing medicines to patients, and for our people, who help make this possible. We're 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment. Over the past 20 years, we've earned a track record of real impact: 60+ advanced candidates, 250 patents filed, and 200+ active projects. Over 90% of our customers choose to stay with us - from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges.
About the role: Our Protein Science team specialises in the engineering, expression, and purification of tailored proteins across a wide range of protein classes for applications including biochemical screening, biophysics, diagnostics, and biologics drug discovery. We also have a dedicated team of scientists carrying out structural studies using X-ray crystallography, Cryo-EM, and protein NMR, giving you the opportunity to work alongside experts across multiple disciplines using cutting-edge technologies. Due to continued growth, we're looking for Scientists and Senior Scientists to join our Protein Science team at our Tytherington site in Macclesfield. We're looking for curious and passionate scientists with hands-on experience in either protein expression, purification, and structural determination. Experience in protein engineering and biophysical or structural characterisation techniques would be an advantage.
As a global CRO, you'll have the opportunity to work across a diverse portfolio of client projects rather than focusing on a single programme. You'll collaborate with talented scientists from across the business, tackle a broad range of scientific challenges, and help our clients accelerate the discovery of tomorrow's medicines. If you're looking for variety, enjoy solving complex scientific problems, and want to be part of a collaborative, innovative team, we'd love to hear from you!
Role Responsibilities:
- Protein Expression involving the expression of recombinant proteins in bacterial, insect, and mammalian systems
- Protein purification and analysis of a broad range of targets including membrane proteins
- Structural Biology - X-ray crystallography, biomolecular NMR, and CryoEM
Skills & Qualifications:
- As a minimum, you will have a BSc/MSc or PhD in Biochemistry or a related discipline
- Drugs discovery experience in a CRO is advantageous; however, it is not essential
- Successful project delivery will be achieved through your own individual experimental work and by working flexibly with colleagues
- Excellent problem-solving skills and knowledge of some of the techniques involved in protein expression, purification, and analysis including structural biology
- Strong interpersonal and communication skills and a natural broader curiosity
Benefits:
- 25 days annual leave (plus bank holidays)
- Private Medical Insurance
- Life Insurance
- Employee Assistance Programme
- Enhanced Family Friendly Policies
- Sygnature Group Pension Scheme
- 1 paid volunteer day per year
Please note: This advert may close early if we receive a high volume of applications. We encourage you to submit your application as soon as possible to avoid missing out on this opportunity.
Scientists/Senior Scientists (Protein and Structure Biology) in Macclesfield employer: Sygnature Discovery Limited
At Sygnature Discovery, we pride ourselves on fostering a collaborative and innovative work culture that empowers our scientists to make significant contributions to life-changing medicines. Located in the picturesque Tytherington area of Macclesfield, our team enjoys a supportive environment with ample opportunities for professional growth, competitive benefits including private medical insurance and enhanced family-friendly policies, and the chance to work on diverse projects that truly make an impact in the field of protein science.
Contact Details:
Sygnature Discovery Limited Recruitment Team
StudySmarter Expert Advice🤫
We think this is how you could land Scientists/Senior Scientists (Protein and Structure Biology) in Macclesfield
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Sygnature Discovery Limited. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Sygnature Discovery Limited!
We think you need these skills to ace Scientists/Senior Scientists (Protein and Structure Biology) in Macclesfield
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Sygnature Discovery Limited that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Sygnature Discovery Limited.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Sygnature Discovery Limited does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Sygnature Discovery Limited
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Sygnature Discovery Limited. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Sygnature Discovery Limited's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Sygnature Discovery Limited. This shows your passion for the industry!
