Medical Science Liaison (UK)

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world-class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people.

Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence. Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology.

Summit has multiple global Phase 3 clinical studies, including:

• Non-small Cell Lung Cancer (NSCLC) HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
• HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
• HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
• HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Summit Therapeutics is seeking an experienced and dynamic Medical Affairs Director to lead the development and implementation of medical strategies for ivonescimab targeting different solid tumor cancers. This role will involve close collaboration with cross-functional teams, including clinical development, regulatory affairs, and commercial operations, to support the investigation and eventual commercialization of ivonescimab in different indications.

The ideal candidate is able to demonstrate effective planning and execution of medical affairs strategies leading to a successful development or adoption of an oncology therapy, as well as ability to analyze, summarize, and deliver complex scientific data to a multitude of audiences.

The Medical Science Liaison (MSL) is a field-based scientific expert specializing in Immuno-Oncology and related treatment options. They play a strategic role in supporting Summit’s scientific and business objectives throughout the oncology product lifecycle. MSLs act as the primary scientific communicators for Summit within their designated regions, engaging with healthcare professionals and supporting clinical site activities.

Combining strong business acumen, clinical expertise, and market awareness, MSLs serve as vital conduits of information to various stakeholders within Summit. Depending on therapeutic needs and product life cycles, their responsibilities may include clinical development and pipeline support.

Role and Responsibilities

• Develop, execute, and maintain high-impact territory plans, including HCP and Investigator engagement plans, aligned with therapeutic area medical and scientific objectives, focusing on quality.
• Identify, gain access to, and develop professional, customer-centric relationships with external experts in Immuno-Oncology within the assigned geography.
• Provide education on disease state, therapeutic landscape, and Summit’s products across the product lifecycle to healthcare providers and researchers.
• Support clinical development, clinical operations, and research initiatives, including site evaluation and identification, recruitment, investigator meetings, external expert identification, and involving experts to generate scientific data, including investigator-sponsored trials.
• Participate, monitor, and provide insights to Summit from relevant scientific meetings within the relevant geography.
• Continuously maintain self-education on market issues and trends, product knowledge, and new therapeutic areas of interest, creating awareness and relationships for Summit in the medical community.
• Create, maintain, and collaborate on relationships with cross-functional partnerships to develop and execute account plans designed to support and meet shared scientific or business objectives.
• Actively participate in relevant team meetings, organizational activities, and country-driven medical affairs activities (e.g., advisory boards, Masterclasses, Round-tables).
• All other duties as assigned.

Experience, Education and Specialized Knowledge and Skills

• Doctoral degree in health sciences from an accredited university (MD, PhD, PharmD, or equivalent).
• Significant clinical and/or industry experience in the oncology therapeutic area may be accepted in lieu of education requirements.
• Lung Cancer clinical experience within the last 5 years is highly desired.
• A minimum of 5+ years of clinical, scientific/research, or industry-related experience or equivalent is preferred.
• A minimum of 2+ years experience as a Medical Science Liaison is required.
• Previous pharmaceutical industry experience within a relevant scientific discipline is preferred.
• The MSL must possess and demonstrate past achievements in:

• Understanding, analyzing, and communicating complicated scientific concepts and data.
• Building credible relationships with prominent HCPs.
• Independently identifying and translating corporate needs into action plans that achieve objectives.
• Self-motivation to achieve and exceed goals.
• Problem-solving and analytic skills.
• Critical thinking.
• Ability to work independently.

Other essential requirements:

• Meeting healthcare industry representative (HCIR) credentialing requirements to enter facilities and organizations within the assigned territory. These may include background checks, drug screens, and proof of immunization/vaccination for various diseases.
• Willingness to travel up to 75% of the time.
• Proficiency in using the standard MS Office suite (e.g., Word, Excel), electronic document management systems, and document review tools.
• Strong computer and database skills.
• Attention to detail, accuracy, and confidentiality.
• Clear and concise oral and written communication skills.
• Excellent organizational skills.
• Ability to effectively multi-task or adapt quickly to changing priorities.
• Ability to manage time-sensitive and highly confidential documents.
• Ability to prioritize conflicting demands.
• Ability to work in a fast-paced, demanding, and collaborative environment.

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labour. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.

Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining a diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.