At a Glance
- Tasks: Own the learning process of AI agents and build environments for experimental work.
- Company: Stealth startup revolutionising AI and biology with a small, elite team.
- Benefits: 30 days annual leave, health cover, pension contributions, and flexible work locations.
- Other info: Dynamic environment with opportunities for growth and collaboration.
- Why this job: Make a real impact in AI for biology while working closely with founders.
- Qualifications: Experience with reinforcement learning, Python, and building agent harnesses.
The predicted salary is between 63000 - 77000 £ per year.
The opportunity
We're a stealth startup in AI and bio, building infrastructure for data generation.
The team is small and elite, the problems are hard, and the foundations are being laid right now.
You'd help write them from the first line, with real ownership and a direct line to the founders.
About us
AI for biology has a data problem.
The data that matters most doesn't exist yet, so we're building the infrastructure to produce it, with quality and traceability built in from day one.
We're in stealth and heads-down on execution.
We'll share more about what we're building once you've spoken with the team.
The role
You will own how our agents learn, which covers building the harnesses and RL environments they work in and post-training the models that run through them.
Our agents work on long-horizon scientific problems, reading papers, querying databases, running code and calling biological models to decide what to test next, and they also need to notice when an experiment has gone wrong.
You will also build environments where agents carry out experimental work, not only plan it.
Rewards in science are noisy, expensive and slow to arrive, so careful reward design matters more than the scale of a run.
When an agent improves, you will work out whether that came from the model itself or from a change in the harness, the tools or the task.
You will report into the intelligence team and work closely with the Bio ML researchers, the evaluation and infrastructure engineers, our software engineers and our scientists.
Who you are
You have trained or post-trained language models and agents with reinforcement learning, and built the tasks, rewards, harnesses and evaluations around them.
You read the traces before trusting an average, and you start from a baseline you trust.
A background in biology is not required, as you will be working closely with our scientists.
- MUST HAVE
- Hands-on experience training LLMs with reinforcement learning, using methods such as PPO or GRPO, including reward design and detecting reward hacking.
- Hands-on experience with RL training frameworks such as ve RL, Miles or TRL, RL environment frameworks such as Harbor or Prime Intellect's verifiers, and inference engines such as v LLM or SGLang.
- Building agent harnesses and long-horizon tasks with tool use, such as search, code execution and external APIs.
- Designing learning signals for long trajectories, including verifiers, LLM judges, process reward models and credit assignment across steps.
- Rigorous comparisons, with matched compute, repeated runs, noise estimates, ablations and held-out problems.
- Clear writing and communication about experiment design, results and what they do and do not show.
- Strong Python and Py Torch, and daily use of coding agents.
- NICE TO HAVE
- Experience applying RL or agents to biological problems, for example with frameworks such as Prot RL.
- Experience with multi-agent setups, such as proposer and critic agents or debate.
- Experience learning from noisy or delayed rewards, and calibrating model confidence.
- Publications, open-source work or public benchmarks in RL, agents or post-training.
- How we work
The role is based in London or San Francisco. We work in the open, write decisions down, and expect each person to own their area and make the calls inside it.
Everyone gets 30 days of annual leave plus local public holidays.
In the UK that comes with a pension with a 10% employer contribution and Bupa private health cover; in the US, a 401(k) with matching and health cover.
We add to these as the team grows.
Our process
Four stages: a screening call, a behavioural interview, an in-person technical session with the team on a real problem from our work, and references.
If you are not sure you fit, apply anyway.
We are an equal opportunity employer.
We make hiring decisions on merit, scope-fit, and the strength of the working relationship we expect to build with each hire.
Applications welcome from candidates of any background.
Member of Technical Staff, Applied RL in London employer: Stealth - AI x Bio
Substrate is an exceptional employer, offering a dynamic work culture that fosters innovation and collaboration at the intersection of AI and biology. Located in London, employees benefit from hands-on experience in cutting-edge molecular characterisation, with ample opportunities for professional growth as they contribute to pioneering automated lab solutions. The company prioritises quality and reproducibility, ensuring that every team member plays a vital role in shaping the future of biological data generation.
StudySmarter Expert Advice🤫
We think this is how you could land Member of Technical Staff, Applied RL in London
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We think you need these skills to ace Member of Technical Staff, Applied RL in London
Some tips for your application 🫡
Show off your coding skills:When applying for a software engineering role, it's super important to showcase your coding skills. Make sure your CV includes your tech stack, any relevant programming languages you’re comfortable with, and examples of projects you've worked on. If you have a GitHub profile, link it up! We love to see code in action.
Tailor your portfolio:For a full-time role, we’d expect to see some solid examples of your work in your portfolio. Make sure to include at least two or three projects that highlight your problem-solving skills and your ability to work with different technologies. Focus on the projects that are most relevant to the position at Stealth - AI x Bio.
Craft a killer cover letter:Your cover letter is your chance to stand out—make it personal! Explain why you want to work at Stealth - AI x Bio and how your skills align with the role. Show us your passion for software development. We dig enthusiastic candidates who understand the value of collaboration and continuous learning!
Be clear and concise:When it comes to writing your CV and cover letter, clarity is key. Avoid jargon that could confuse us and stick to simple, direct language. Highlight your achievements with quantifiable results where possible, and keep everything easy to read. A well-organised application goes a long way!
How to prepare for a job interview at Stealth - AI x Bio
✨Brush Up on Your Coding Skills
For a full-time software engineering role, it's crucial that we stay sharp with our coding abilities. Expect technical questions that might involve solving problems on the spot or discussing algorithms. Practise on platforms like LeetCode or HackerRank to get comfortable with the types of questions that often come up.
✨Know Your Tools and Frameworks
Make sure we’re well-acquainted with the tools and technologies listed in the job description. Familiarise ourselves with any specific frameworks or programming languages mentioned. If Stealth - AI x Bio uses React or Node.js, for instance, be ready to discuss how we’ve used them in previous projects or coursework.
✨Showcase Your Projects
Bring along a portfolio that highlights our best work. This could be code samples, GitHub repositories, or any side projects we’ve built. Make sure we can talk through our thought process for each project, especially the challenges we faced and how we solved them—this shows our problem-solving skills in action.
✨Prepare for Behavioural Questions
While technical skills are key, full-time positions also require cultural fit. Be ready to discuss our previous experiences and how we handle teamwork, conflict, and deadlines. Brush up on the STAR method—Situation, Task, Action, Result—to clearly articulate our past experiences when discussing how we've contributed to a team.