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For Companies At a Glance
- Tasks: Join a global team to optimise and validate cutting-edge histology techniques.
- Company: Leading pharmaceutical company focused on innovative drug discovery.
- Benefits: 12-month contract with competitive pay and opportunities for professional growth.
- Why this job: Make a real impact in drug discovery through advanced molecular histology.
- Qualifications: Extensive experience in histology techniques and strong collaboration skills.
- Other info: Dynamic lab environment with a focus on innovation and teamwork.
The predicted salary is between 48000 - 72000 ÂŁ per year.
Title
Title: Senior Scientist
Location: Stevenage (Onsite)
Contract Length: 12 months
Rate: ÂŁ26.97 per hour
About the Team
Large Molecule Research (LMR) discovers and engineers antibody and protein therapeutics—from early discovery through expression, characterisation, molecular engineering and biophysical profiling. Within LMR, the Molecular Design & Engineering (MDE) group focuses on antibody engineering and developability profiling to transform discovered leads into high‑quality therapeutic candidates prior to candidate selection.
The Opportunity
We’re seeking an analytical scientist to join the Developability team within MDE. This lab‑centric role profiles/characterises panels of biopharmaceuticals (e.g., antibodies, Fc‑fusions, novel modalities) for biophysical liabilities and stability, and partners with early project teams to interpret data and influence design decisions.
What you’ll do (Key Responsibilities)
- Plan, design and execute biophysical experiments to characterise proteins (e.g., SEC/SEC‑MALS, DLS, DSF/thermal shift, chromatography‑based methods; mass spectrometry exposure advantageous).
- Assess developability risks (aggregation/colloidal stability, thermal stability, heterogeneity) and provide clear go/no‑go or mitigation recommendations.
- Interpret and communicate findings (written & oral) to cross‑functional, non‑expert audiences (discovery biology, protein engineering, CMC).
- Maintain high-quality documentation in electronic lab notebooks (ELN) and author concise study reports.
- Support method optimisation/automation (liquid handlers where applicable) and routine instrument upkeep/troubleshooting.
- Contribute to platform improvements (buffers, stress‑test panels, data analysis templates) and to data integrity/compliance best practices.
Minimum Qualifications (Basic)
- PhD (or 2–3 years equivalent industry/academic experience) in Biophysics, Biochemistry, Biopharmaceutical Sciences or related discipline.
- Hands‑on experience characterising proteins using one or more of: Dynamic Light Scattering (DLS), Analytical Size Exclusion (SEC), Differential Scanning Fluorimetry (DSF), chromatography methods (e.g., SEC‑MALS, IEC), or mass spectrometry.
- Strong analytical and data interpretation skills; ability to translate data into actionable project guidance.
Nice to Have (Preferred)
- Experience with automated liquid handlers for assay set‑up.
- Familiarity with antibody discovery/engineering workflows and developability concepts.
- Experience measuring protein–protein interactions by Surface Plasmon Resonance (SPR) or related biophysical methods (e.g., BLI, MST).
- Exposure to formulation/stability assessments and stress studies.
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Senior Scientist employer: SRG
Contact Detail:
SRG Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist
✨Tip Number 1
Network like a pro! Reach out to professionals in the pharmaceutical industry, especially those working in histology. Use platforms like LinkedIn to connect and engage with them. You never know who might have the inside scoop on job openings!
✨Tip Number 2
Prepare for interviews by brushing up on your technical skills. Be ready to discuss your experience with IHC/IF antibody optimisation and multiplex protocols. Practise explaining complex concepts in simple terms – it shows you really know your stuff!
✨Tip Number 3
Don’t just apply and wait! Follow up on your applications through our website. A quick email or message can show your enthusiasm and keep you on their radar. It’s all about making that personal connection!
✨Tip Number 4
Showcase your passion for molecular histology in every interaction. Whether it’s in interviews or networking events, let your enthusiasm shine through. Employers love candidates who are genuinely excited about their work!
We think you need these skills to ace Senior Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Senior Scientist role. Highlight your experience with IHC/IF antibody optimisation and any relevant projects you've worked on. We want to see how your skills match what we're looking for!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about molecular histology and how your background makes you a great fit for our team. Keep it engaging and personal – we love to see your personality!
Showcase Relevant Experience: When detailing your experience, focus on specific projects where you've optimised or validated antibody clones or developed multiplex protocols. We want to know how you've tackled challenges in the lab and what results you achieved!
Apply Through Our Website: Don't forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it gives you a chance to explore more about us and what we do!
How to prepare for a job interview at SRG
✨Know Your Techniques Inside Out
Make sure you brush up on your knowledge of IHC/IF antibody clones and ISH probe assays. Be ready to discuss specific techniques you've used, including any challenges you faced and how you overcame them. This shows you're not just familiar with the theory but have practical experience too.
✨Showcase Your Collaborative Spirit
Since the role involves working closely with Discovery pathologists and project teams, be prepared to share examples of how you've successfully collaborated in the past. Highlight your communication skills and how you maintain timely updates with stakeholders, as this is crucial for the job.
✨Demonstrate Your Problem-Solving Skills
Think of instances where you had to troubleshoot or optimise protocols under tight deadlines. Discuss your approach to identifying project needs and how you adapt to new technologies. This will show that you can think on your feet and contribute effectively to the team.
✨Prepare Questions That Matter
Have a few insightful questions ready about the company's projects or the specific technologies they use. This not only shows your interest in the role but also your proactive attitude towards understanding how you can fit into their team and contribute to their goals.
