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- Tasks: Lead innovative projects in enzymology and biochemistry to tackle cancer targets.
- Company: Join a cutting-edge organisation dedicated to advancing drug discovery and oncology research.
- Benefits: Enjoy a permanent position with opportunities for professional growth and collaboration.
- Why this job: Make a real impact in cancer research while working with top scientists in the field.
- Qualifications: PhD in Enzymology or Pharmacology with significant experience in drug discovery required.
- Other info: Be part of a dynamic team that values creativity and scientific excellence.
The predicted salary is between 48000 - 72000 £ per year.
Principal Scientist – Enzymology Cambridge Permanent SRG are currently supporting the search for a Principal Scientist with an expertise in enzymology. You will be an inspirational scientist with an exceptional record of bringing your deep knowledge of enzymology and biochemistry to impact on projects. Within this role you will be brining scientific leadership to the design of biochemical assays and bespoke mechanistic data helping to characterise cancer targets. The Role: Provide scientific leadership to define and implement best practice for biochemical assays and bespoke mechanism of action studies. Design and develop novel physiologically relevant biochemical assays for a range of target classes, using recombinant proteins Characterise cancer targets in detail at the molecular level Define biochemical profiling cascade to support characterisation of novel small molecules for oncology targets Characterise small molecules in vitro using recombinant proteins and a range of biochemical assay technologies, with a particular focus on detailed kinetic and mechanism of inhibition studies and their translation into the cellular environment. Represent the department across a broad range of projects and cross-site initiatives, both internally and externally. Prioritise own work and that of line reports according to project goals and take responsibility for the timely delivery of team objectives Manage performance and development of line reports Requirements: PhD (or equivalent) in Enzymology, Pharmacology, or equivalent experience Significant experience and deep expertise in enzymology in a drug discovery environment Detailed understanding of steady-state and pre-steady-state enzymology. Experience in Modelling and Simulation will be an advantage. Detailed theoretical and practical understanding of biochemical assays and detection technologies, with a particular focus on physiologically relevant systems Significant experience of assay development for a range of target classes Strong external reputation in enzymology, evidenced through wide personal network, external presentation and publication, and presentation at key conferences. Apply now by attaching your CV in Word, or contact Paige Keenan for further information about this new role:
Principal Scientist employer: SRG
Contact Detail:
SRG Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist
✨Tip Number 1
Network with professionals in the enzymology and drug discovery fields. Attend relevant conferences and seminars to meet potential colleagues and industry leaders, as this can help you gain insights into the latest trends and opportunities.
✨Tip Number 2
Engage with online communities and forums related to enzymology and biochemistry. Sharing your knowledge and experiences can help you build a reputation and connect with others who may know about job openings.
✨Tip Number 3
Consider reaching out to current or former employees of StudySmarter or similar companies. Informational interviews can provide valuable insights into the company culture and expectations for the Principal Scientist role.
✨Tip Number 4
Stay updated on the latest research and advancements in enzymology and drug discovery. Being knowledgeable about recent developments will not only enhance your expertise but also demonstrate your passion for the field during interviews.
We think you need these skills to ace Principal Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your expertise in enzymology and biochemistry. Focus on relevant experiences, particularly those related to drug discovery and biochemical assay development.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for the role and the impact you can make. Mention specific projects or achievements that demonstrate your scientific leadership and experience in characterising cancer targets.
Highlight Relevant Skills: In your application, emphasise your understanding of steady-state and pre-steady-state enzymology, as well as any experience with modelling and simulation. This will show that you meet the job requirements.
Showcase Your Network: If applicable, mention your external reputation in enzymology, including any presentations at key conferences or publications. This can help establish your credibility and fit for the role.
How to prepare for a job interview at SRG
✨Showcase Your Expertise
Make sure to highlight your deep knowledge of enzymology and biochemistry during the interview. Prepare specific examples of past projects where you successfully designed biochemical assays or characterised cancer targets, as this will demonstrate your capability and experience.
✨Discuss Leadership Experience
Since the role requires scientific leadership, be ready to discuss your experience in managing teams and projects. Share instances where you prioritised work effectively and delivered team objectives on time, showcasing your ability to lead and inspire others.
✨Prepare for Technical Questions
Expect technical questions related to steady-state and pre-steady-state enzymology, as well as biochemical assay development. Brush up on these topics and be prepared to explain complex concepts clearly, demonstrating your theoretical and practical understanding.
✨Network and Reputation
Given the importance of having a strong external reputation, be prepared to discuss your professional network and any relevant presentations or publications. This can help establish your credibility and show that you are well-connected in the field of enzymology.
