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- Tasks: Lead a team in innovative drug discovery projects and develop human cell assays.
- Company: Join a groundbreaking organization focused on discovering future medicines.
- Benefits: Competitive salary and the chance to work with cutting-edge technologies.
- Why this job: Make an impact in therapeutic development while collaborating with top scientists.
- Qualifications: PhD in cell/molecular biology with experience in drug discovery and assay development.
- Other info: Opportunity for leadership and collaboration in a dynamic research environment.
The predicted salary is between 43200 - 72000 £ per year.
Principal Scientist – Cell and Molecular Biology
Cheshire
Permanent
£ Competitive
SRG is delighted to be partnering with groundbreaking organisation that is developing new approaches for discovering the medicines of the future. They are now looking for a motivated self-starter to provide scientific and project leadership to deliver collaborative projects and build new capabilities via innovation and integration of the latest technologies.
The successful candidate will also apply their expertise in cell and molecular biology, together with understanding of novel therapeutic strategies and complex medicines to deliver impactful results characterising cellular target engagement and target validation studies and prosecuting therapeutic efficacy assays in vitro.
Main Duties:
- Lead a team of scientists with effective line management and matrix management of projects
- Establish and lead collaborations to develop solutions in drug discovery programmes.
- Lead the development of human cell assays for the evaluation of a wide range of small molecule, large molecule and novel therapeutics.
- Establish and validate experimental endpoints for medicine evaluation to industry standards.
- Design and deliver strategies to evaluate phenotypic responses of multiple cell populations and complex cell models and tissue samples including the assessment of therapeutic efficacy.
- Act as the in vitro technical expert for complex medicine evaluation
- Work in partnership with scientists in the fields of complex cell models, preclinical imaging, target engagement and target validation, in vitro and in vivo to deliver end-to-end workflows that can be applied to collaborative projects.
Ideal Candidate:
- PhD (or equivalent) in cell or molecular biology with relevant postdoctoral experience in therapeutic characterisation
- Experience of working in drug discovery, and developing in vitro assays ideally in an industry setting
- Extensive experience in molecular engineering of cells including lentiviral transduction, CRISPR techniques and molecular analysis technologies.
- Extensive experience in culture of mammalian cells including background of working with primary cells and iPSC derivatives and analysis of phenotypic responses.
- Experience in novel therapeutic approaches, for example with particular expertise in lipid nanoparticles, cancer vaccines, ADCs or other complex medicines.
- Proven expertise and good publication record in cell and molecular biology.
- Experience in line management and leadership of a team of scientists.
- Proven track record of leading and delivering projects in a collaborative environment with the ability to work on multiple projects simultaneously.
If you are interest in applying, then please use an updated copy of your CV in word or alternatively reach out to Paige Keenan for more information: paige.keenan@srgtalent.com
Principal Scientist employer: SRG
Contact Detail:
SRG Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist
✨Tip Number 1
Make sure to highlight your leadership experience in your conversations. As a Principal Scientist, you'll be expected to lead a team and manage projects effectively, so showcasing your past successes in these areas will set you apart.
✨Tip Number 2
Network with professionals in the field of cell and molecular biology. Attend relevant conferences or webinars where you can meet potential colleagues or collaborators who might provide insights into the company culture and expectations.
✨Tip Number 3
Stay updated on the latest advancements in therapeutic strategies and complex medicines. Being knowledgeable about current trends and technologies will demonstrate your passion and commitment to innovation during discussions.
✨Tip Number 4
Prepare to discuss specific examples of your work with in vitro assays and drug discovery. Having concrete examples ready will help you illustrate your expertise and how it aligns with the company's goals.
We think you need these skills to ace Principal Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your PhD and relevant postdoctoral experience in cell and molecular biology. Emphasize your expertise in drug discovery and any specific techniques like CRISPR or lentiviral transduction that are mentioned in the job description.
Craft a Strong Cover Letter: Write a cover letter that showcases your motivation and leadership skills. Discuss your experience in managing teams and projects, and how you can contribute to the innovative drug discovery programs of the organization.
Highlight Collaborative Experience: In your application, emphasize any previous collaborative projects you've worked on. Detail your role in these projects and how you successfully led teams or established partnerships to achieve impactful results.
Proofread Your Application: Before submitting, carefully proofread your CV and cover letter for any errors. Ensure that all information is clear, concise, and tailored to the job description to make a strong impression.
How to prepare for a job interview at SRG
✨Showcase Your Leadership Skills
As a Principal Scientist, you'll be expected to lead a team effectively. Prepare examples of how you've successfully managed projects and guided teams in the past. Highlight your experience in line management and collaborative environments.
✨Demonstrate Technical Expertise
Be ready to discuss your hands-on experience with cell and molecular biology techniques, especially those relevant to drug discovery. Familiarize yourself with the latest technologies and therapeutic strategies that are currently shaping the field.
✨Prepare for Collaborative Scenarios
Since collaboration is key in this role, think of instances where you've worked with cross-functional teams. Be prepared to discuss how you established partnerships and what strategies you used to ensure successful project outcomes.
✨Discuss Your Research Impact
Your publication record is important, so be ready to talk about your research contributions. Focus on how your work has led to impactful results in therapeutic efficacy assays or other relevant areas, and how it aligns with the company's goals.
