Scientist, LNP Process and Development in Cambridge

Scientist, LNP Process and Development in Cambridge

Cambridge Full-Time 80000 - 100000 £ / year (est.) No working from home possible
Serif Biomedicines

At a Glance

  • Tasks: Join us in developing innovative lipid nanoparticle formulations for groundbreaking nucleic acid delivery.
  • Company: Be part of Serif Biomedicines, a pioneering biotech company transforming medicine with Modified DNA.
  • Benefits: Enjoy competitive pay, healthcare coverage, and a collaborative, science-driven culture.
  • Other info: Dynamic team environment with opportunities for professional growth and innovation.
  • Why this job: Make a real impact in biotechnology while working on cutting-edge research and development.
  • Qualifications: PhD or equivalent experience in relevant fields, with a strong background in process development.

The predicted salary is between 80000 - 100000 £ per year.

Serif Biomedicines is a privately held, early-stage biotechnology company pioneering Modified DNA as a new class of medicines. Modified DNA brings together the best features of mRNA and gene therapy, while mitigating their limitations, by enabling medicines that are durable, redosable, programmable, and scalable.

We are seeking a highly motivated Scientist to support the development and scale-up of lipid nanoparticle (LNP) formulations for nucleic acid delivery. This role will focus on process optimization and scale-up of targeted LNPs encapsulating modified DNA and cofactor mRNA, while also contributing to research efforts aimed at improving LNP design and performance. This is an ideal opportunity for a scientist with a strong background in process development who is interested in expanding into formulation development and early-stage R&D, including formulation screening and optimization of next-generation LNP systems. The successful candidate will work collaboratively within cross-functional teams to advance LNP platform capabilities and support the development of scalable and robust nucleic acid delivery systems.

Key responsibilities:

  • Support process development and optimization activities for LNP formulation and scale-up, including mixing parameters, encapsulation efficiency, and reproducibility.
  • Design and execute experiments to improve the performance and manufacturability of LNPs encapsulating modified DNA and mRNA.
  • Collaborate with internal and external teams to support characterization and evaluation of LNP formulations.
  • Assist with technology transfer and scale-up activities, including coordination with external partners or internal manufacturing teams.
  • Analyze and interpret experimental data, maintain accurate documentation, and communicate findings to project teams.
  • Stay current with advancements in LNP technologies and nucleic acid delivery approaches.

Professional experience and qualifications:

  • PhD in Chemical Engineering, Pharmaceutical Sciences, Bioengineering, or a related field, with 3+ years of relevant industry experience; M.S. with 8+ years of experience; or Bachelor with 10+ years of experience.
  • Strong background in process development, scale-up, or manufacturing of nanoparticle or LNP-based systems.
  • Experience working with nucleic acid formulations (e.g., mRNA, DNA) is highly preferred.
  • Familiarity with T mixing, or similar, formulation scale-up, and characterization techniques (e.g., DLS, encapsulation assays).
  • Demonstrated ability to design experiments, analyze data, and solve complex technical problems.
  • Strong communication and collaboration skills.

What We Offer:

  • Opportunity to work at the forefront of LNP formulation innovation.
  • Collaborative, science-driven culture with high impact research.
  • Competitive compensation and benefits package.

Scientist, LNP Process and Development in Cambridge employer: Serif Biomedicines

At Serif Biomedicines, we pride ourselves on being at the cutting edge of biotechnology, offering a collaborative and science-driven culture that fosters innovation and impactful research. Our employees benefit from competitive compensation, comprehensive healthcare coverage, and robust retirement plans, all while working in an environment that encourages professional growth and development in the exciting field of lipid nanoparticle formulation. Join us in our mission to transform human health and sustainability, where your contributions will make a meaningful difference.

Serif Biomedicines

Contact Details:

Serif Biomedicines Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Scientist, LNP Process and Development in Cambridge

Get Involved in Local Research Communities

Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!

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Show Off Your Projects

Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!

Stay Up-to-Date with Industry Trends

Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Serif Biomedicines!

We think you need these skills to ace Scientist, LNP Process and Development in Cambridge

Process Development
Scale-Up Techniques
Lipid Nanoparticle (LNP) Formulation
Nucleic Acid Delivery
Experimental Design
Data Analysis
Collaboration Skills

Some tips for your application 🫡

Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Serif Biomedicines that you have the hands-on skills they need.

Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Serif Biomedicines.

Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Serif Biomedicines does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.

Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.

How to prepare for a job interview at Serif Biomedicines

Brush Up on Lab Techniques

Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Serif Biomedicines. You might even be asked to demonstrate your understanding of these processes.

Know Your Bioinformatics Tools

Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.

Show Your Teamwork Skills

Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Serif Biomedicines's culture.

Research Recent Biotech Innovations

Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Serif Biomedicines. This shows your passion for the industry!