4d Printed Biomaterials In Cancer Therapeutics

# 4D printed Biomaterials in cancer therapeuticsPh.D·The Queen’s University Belfast·School of Pharmacy·United KingdomPosition type: StudentshipLevel: Ph.DLanguage: English## About the PositionAccording to WHO, cancer is the second leading cause of death worldwide, with nearly 1 in 6 deaths been due to cancer. The principal modes of cancer management are surgery, radiotherapy, chemotherapy and pharmaceutical agents. However, there are many side effects from extant treatments e.g., invasiveness of surgery, and with other treatments being systemic in nature; therefore, only a small fraction of the drugs reaches the tumour site. Due to the short period of actions, repeated doses are often required, which can lead to exacerbation of side effects and inconvenience. Due to these obstacles, targeted or localized release technology coupled with long-acting treatment functionality is a key research theme to replace systemic administration therapies and show potential for advancing cancer treatment including capability of personalizing the treatment. One especially promising therapeutic option gaining prominence is the use of multifunctional implants combining tumour-killing ability while promoting bone resorption/growth. Therefore, the main goal of this project is to investigate new approaches for targeted long-acting drug release for effective cancer therapies based on 3D & 4D printed / bioprinted drug-loaded implants.Subject areaCancer management, Bioprinting, Biomaterials, drug deliveryCandidate requirements / Key skills required for the postApplicants should have a 1st or 2.1 honours degree (or equivalent) in a relevant subject. Relevant subjects include Pharmacy, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline. Students who have a 2.2 honours degree and a Master’s degree may also be considered, but the School reserves the right to shortlist for interview only those applicants who have demonstrated high academic attainment to date.Relevant links / more informationhttp://www.qub.ac.uk/schools/SchoolofPharmacy/Research/PostgraduatePositions/http://www.qub.ac.uk/schools/SchoolofPharmacy/Research/Keywords for search filters3D Printing, 4D printing, Bioprinting, Drug Delivery, Cancer treatment, ImplantsTraining provided through the research projectThe successful applicant will be integrated into QUB research groups of experienced researchers with access to world-leading facilities. The techniques that will be used during the project cover a wide-range and include: Atomic Force Microscope (AFM), Computed Tomography (CT), Contact Angle Goniometry (CAG), Differentia## Research Interests* Investigate targeted long-acting drug release using printed and bioprinted implants* Disseminate findings through talks, conferences and publications* Participate in university showcase events## Required Skills & Qualifications* Relevant 1st or 2.1 honours degree or equivalent* A 2.2 honours degree with a Master's degree may be considered #J-18808-Ljbffr