Senior Research Associate, High-Throughput RNA Production in Cambridge

Senior Research Associate, High-Throughput RNA Production in Cambridge

Cambridge Full-Time 44595 - 54505 £ / year (est.) No working from home possible
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At a Glance

  • Tasks: Generate RNAs and advance cutting-edge programmable circular RNA technology.
  • Company: Join Sail Biomedicines, a pioneer in programmable medicines transforming patient care.
  • Benefits: Competitive salary, collaborative environment, and opportunities for real-world impact.
  • Other info: Fast-paced environment with strong focus on collaboration and career growth.
  • Why this job: Be part of a team making breakthroughs in medicine with innovative technology.
  • Qualifications: B.S. in Life Sciences or related field with relevant research experience.

The predicted salary is between 44595 - 54505 £ per year.

About Sail

Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care. Sail’s platform combines first-in-class programmable circular RNA technology (Endless RNA™ or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is also making unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.

The Role

The Senior Research Associate, high-throughput (HTP) RNA production, serves an important role in generating RNAs to advance Sail’s first-in-class programmable circular RNA technology (Endless RNA™ or eRNA). This role will carry out end-to-end process of high-throughput RNA production, from template plasmid cloning to RNA generation and clean up. The successful candidate is organized, attentive to details, a fast learner with a strong sense of responsibility who takes pride in his/her work. The team looks forward to helping you strive in this exciting and fast-paced environment to make a real-world impact on patients’ lives.

Responsibilities

  • Perform high-throughput cloning of plasmid constructs and RNA generation through in vitro transcription (IVT)
  • Determine circularization efficiency and impurity levels by running analytic assays
  • Coordinate DNA synthesis and scale-up orders with external vendors
  • Manage raw material and RNA inventories
  • Collaborate with automation engineer to improve process workflow
  • Maintain detailed documentation in electronic lab notebooks
  • Present findings clearly to platform teams and contribute to scientific discussions and decision-making

Qualifications

  • B.S. in Life Sciences, Chemistry, Engineering, or a related field with 2+ years of relevant full-time industry or academic research experience, or M.S. in Life Sciences
  • Ability to manage multiple tasks at once efficiently
  • Strong collaborative spirit and communication skills
  • Excellent record keeping

Preferred Qualifications

  • Experience in molecular biology including cloning, RNA production and purification
  • Familiarity with high-performance liquid chromatography (HPLC) or other column-based purification/analytic methods
  • Experience with automated liquid handling systems (e.g., Hamilton) and high-throughput laboratory workflows
  • Experience using data analysis and information management tools, such as Excel, Graphic Prism, SnapGene, Benchling
  • Experience in inventory management

Salary Range: $75,000 - $95,000

Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.

Senior Research Associate, High-Throughput RNA Production in Cambridge employer: sail biomedicines

Sail Biomedicines is an exceptional employer, offering a dynamic and innovative work environment where employees can contribute to groundbreaking advancements in programmable medicines. With a strong emphasis on collaboration and professional growth, team members are encouraged to develop their skills while making a meaningful impact on patient care. Located in a fast-paced setting, Sail provides unique opportunities to work with cutting-edge technology and be part of a mission-driven organisation dedicated to transforming healthcare.

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Contact Details:

sail biomedicines Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Research Associate, High-Throughput RNA Production in Cambridge

Get Involved in Local Research Communities

Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!

Leverage University Alumni Networks

If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like sail biomedicines. You'd be surprised how willing people are to help out a fellow grad!

Show Off Your Projects

Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!

Stay Up-to-Date with Industry Trends

Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like sail biomedicines!

We think you need these skills to ace Senior Research Associate, High-Throughput RNA Production in Cambridge

High-Throughput Cloning
RNA Generation
In Vitro Transcription (IVT)
Analytic Assays
DNA Synthesis Coordination
Inventory Management
Collaboration with Automation Engineers

Some tips for your application 🫡

Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show sail biomedicines that you have the hands-on skills they need.

Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at sail biomedicines.

Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that sail biomedicines does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.

Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.

How to prepare for a job interview at sail biomedicines

Brush Up on Lab Techniques

Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at sail biomedicines. You might even be asked to demonstrate your understanding of these processes.

Know Your Bioinformatics Tools

Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.

Show Your Teamwork Skills

Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into sail biomedicines's culture.

Research Recent Biotech Innovations

Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at sail biomedicines. This shows your passion for the industry!