At a Glance
- Tasks: Conduct innovative experiments to advance cutting-edge RNA technology and improve patient care.
- Company: Join Sail Biomedicines, a pioneer in programmable medicines and transformative healthcare.
- Benefits: Competitive salary, inclusive culture, and opportunities for impactful research.
- Other info: Dynamic team environment with excellent career growth potential.
- Why this job: Make a real-world impact on patients' lives with groundbreaking RNA science.
- Qualifications: Ph.D. or M.S. with extensive RNA research experience and strong problem-solving skills.
Sail Biomedicines is pioneering the integrative design and deployment of fully programmable medicines to transform patient care. Sail’s platform combines first-in-class programmable circular RNA technology (Endless RNA™ or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is also making unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable.
The Scientist, Platform RNA Sciences, will work on key projects to advance Sail’s first-in-class programmable circular RNA technology (Endless RNA™ or eRNA). This role works cross-functionally to perform hypothesis-driven experiments and high-throughput screens to improve our eRNA designs, with the goal to maximize circularization, and enhance RNA stability and translation. The successful candidate is self-motivated, curious and creative, thinks outside of the box and has a can-do mindset. The team looks forward to helping you strive in this exciting and fast-paced environment to make a real-world impact on patients’ lives.
Responsibilities
- Conceive and conduct pooled and array screens to improve our eRNA designs, enabling higher product purity and function
- Design hypothesis-driven experiments based on state-of-the-art RNA biology to refine our eRNA designs
- Evaluate and develop alternative circularization strategies
- Determine circularization efficiency and impurity levels by running analytic assays
- Design properly controlled experiments, generate high-quality data, and run rigorous statistical analysis
- Maintain detailed documentation in electronic lab notebooks
- Author standard operating procedures (SOPs), study summaries, and technical reports
- Present findings clearly in oral or written formats to internal and external stakeholders to enable alignment and decision-making
Qualifications
- Ph.D. in Molecular Biology, Biochemistry, or a related field, or M.S. with 6+ years of focused, full-time research experience in RNA technologies
- Strong background in RNA biology with demonstrated skillset in relevant molecular and biochemical techniques, such as in vitro transcription (IVT), RNA purification, oligo-dT purification, column chromatography, capillary gel electrophoresis, RT-qPCR, RNA-seq, Nanopore sequencing
- Experience using data analysis and information management tools, such as Excel, Graphic Prism, R, JMP, SnapGene, Benchling, Smartsheet, Jira
- Excellent problem-solving skills with the ability to independently design and carry out experiments
- Ability to manage multiple tasks at once while knowing how to prioritize
- Strong collaborative spirit and excellent organizational and communication skills
- Excellent record keeping
Preferred Qualifications
- Experience in Next Generation Sequencing (NGS) library preparation
- Working knowledge in engineering ribozyme, aptamer or other complex RNA structures
Salary Range: $98,000 - $125,000
Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
Scientist, Platform RNA Sciences in Cambridge employer: sail biomedicines
Sail Biomedicines is an exceptional employer, offering a dynamic and innovative work environment where employees can contribute to groundbreaking advancements in programmable medicines. With a strong emphasis on collaboration and professional growth, team members are encouraged to develop their skills while making a meaningful impact on patient care. Located in a fast-paced setting, Sail provides unique opportunities to work with cutting-edge technology and be part of a mission-driven organisation dedicated to transforming healthcare.
StudySmarter Expert Advice🤫
We think this is how you could land Scientist, Platform RNA Sciences in Cambridge
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like sail biomedicines. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like sail biomedicines!
We think you need these skills to ace Scientist, Platform RNA Sciences in Cambridge
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show sail biomedicines that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at sail biomedicines.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that sail biomedicines does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at sail biomedicines
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at sail biomedicines. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into sail biomedicines's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at sail biomedicines. This shows your passion for the industry!
