At a Glance
- Tasks: Design and develop lipid nanoparticle formulations for cutting-edge nucleic acid therapeutics.
- Company: Join Sail Biomedicines, a leader in innovative drug delivery solutions.
- Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
- Other info: Collaborative environment with a focus on innovation and career development.
- Why this job: Make a real impact in the biotech field while advancing your scientific career.
- Qualifications: 4+ years of experience in LNP formulation and a strong background in life sciences.
The predicted salary is between 42750 - 52250 £ per year.
Sail Biomedicines is seeking a scientist to advance our lipid nanoparticle (LNP) manufacturing platform for nucleic acid therapeutics. The successful candidate will contribute to preclinical pipeline programs, working at the interface of manufacturing, formulation science, analytical characterization, and process development.
KEY RESPONSIBILITIES
- Design, formulate, and characterize lipid nanoparticle (LNP) systems for nucleic acid delivery across preclinical manufacturing and technology development stages.
- Develop, optimize and operationalize formulation processes and scale-up approaches (e.g., TFF, ultrafiltration).
- Troubleshoot formulation and process challenges to enhance robustness, reproducibility, and scalability.
- Generate high-quality, reproducible data and maintain thorough documentation in electronic lab notebooks.
- Prepare LNP formulations to support internal research and partner programs.
- Collaborate cross-functionally with analytical, translational and platform teams to advance preclinical manufacturing and pilot lab goals.
- Present data and insights clearly to internal teams and contribute to scientific discussions and decision-making.
PROFESSIONAL EXPERIENCE & QUALIFICATIONS
- 4+ years (M.Sc.) or 6+ years (B.Sc.) of relevant industry experience in LNP formulation optimizations and drug delivery with a strong background in nucleic acid therapeutics and education in life sciences or engineering (Pharmaceutical Sciences, Biomedical Engineering, Biochemistry, etc).
- Level (Associate Scientist or Scientist I) will be determined based on experience, technical expertise, and demonstrated impact.
- Hands-on experience in nanoparticle or LNP formulation and characterization.
- Strong understanding of drug delivery systems, particularly for nucleic acid therapeutics.
- Experience with nanoparticle characterization techniques (e.g., DLS, zeta potential, fluorescence-based assays such as Ribogreen, chromatography).
- Demonstrated ability to design, execute, and troubleshoot experiments independently.
- Strong data analysis, documentation, and communication skills.
PREFERRED QUALIFICATIONS
- Familiarity with formulation process technologies (e.g., microfluidic mixers, pumping systems, TFF).
- Experience supporting in vivo studies or translating formulations from research to preclinical scale.
Salary Range: $95,000 - $120,000. Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
Associate Scientist, Formulation, Pilot Lab in Cambridge employer: sail biomedicines
Sail Biomedicines is an exceptional employer, offering a dynamic and innovative work environment where employees can contribute to groundbreaking advancements in programmable medicines. With a strong emphasis on collaboration and professional growth, team members are encouraged to develop their skills while making a meaningful impact on patient care. Located in a fast-paced setting, Sail provides unique opportunities to work with cutting-edge technology and be part of a mission-driven organisation dedicated to transforming healthcare.
