Executive Director, Evidence Synthesis & Statistics in Manchester

Executive Director, Evidence Synthesis & Statistics in Manchester

Manchester Full-Time No working from home possible
RTI International

At a Glance

  • Tasks: Lead and grow evidence synthesis services, delivering high-quality analytical solutions for global clients.
  • Company: Join a leading health solutions provider focused on innovative evidence generation.
  • Benefits: Competitive salary, professional development, and opportunities to mentor a high-performing team.
  • Other info: Engage with the research community and contribute to advancing methodologies in a dynamic environment.
  • Why this job: Make a real impact in healthcare by driving innovation and strategic decision-making.
  • Qualifications: Advanced degree and 12+ years of experience in evidence synthesis and statistical methods.

RTI Health Solutions (RTI-HS) is a leading provider of global health economics and outcomes research (HEOR), real-world evidence (RWE), epidemiology, and market access consulting services to the biopharmaceutical, medical device, and diagnostics industries. Our multidisciplinary teams partner with clients across the product lifecycle to generate evidence that informs regulatory, reimbursement, and commercialization decisions. The Evidence Synthesis & Statistics (ESS) capability plays an important role in helping clients evaluate the clinical, humanistic, and economic value of healthcare interventions.

The team delivers evidence synthesis, advanced statistical analysis, and strategic evidence planning to support HTA, regulatory, payer, market access, and evolving Joint Clinical Assessment (JCA) decision‑making globally. We are seeking an accomplished scientific leader to lead and grow RTI-HS’s ESS capability. This individual will provide strategic, scientific, and operational leadership for evidence synthesis and statistical services while remaining hands‑on in the delivery of complex client work.

What You’ll Do

  • Provide scientific, strategic, and operational leadership for RTI-HS’s evidence synthesis services.
  • Lead and grow RTI-HS’s Evidence Synthesis & Statistics capability, establishing a market‑leading practice focused on evidence generation, advanced analytics, and decision support.
  • Serve as a senior scientific advisor to pharmaceutical and biotechnology clients on evidence synthesis methodologies and evidence generation strategy.
  • Provide technical leadership, hands‑on methodological input, and quality assurance across a wide range of evidence synthesis activities.
  • Lead and directly contribute to complex analytical work, including projects involving Bayesian methods, causal inference, patient‑reported outcomes analysis, survival analysis, mixed effects/hierarchical modeling, network meta‑analysis, and other indirect treatment comparisons.
  • Advise on integrated evidence strategies aligning clinical development, HEOR, RWE, market access, and publication objectives.
  • Drive innovation in methods, ensuring adoption of new and evolving approaches and continuous improvement in delivery.

Business Development & Client Leadership

  • Lead business development activities, including identifying opportunities, developing proposals, supporting client presentations and scientific meetings, and contributing senior scientific insight throughout the sales process.
  • Partner with commercial and scientific leaders across RTI‑HS to expand the visibility and position of the ESS capability.
  • Act as a senior client contact, building long‑term relationships and providing strategic and methodological input across engagements.
  • Monitor industry trends, HTA, payer, and evolving JCA evidence requirements, and competitive landscape to inform service development.

Operational & People Leadership

  • Build, mentor, coach, and develop a high‑performing team of evidence synthesis statisticians.
  • Oversee project delivery to ensure scientific rigour, client satisfaction and financial performance.
  • Lead complex projects and portfolios, ensuring alignment to timelines, budgets, quality standards, and client expectations.

Thought Leadership & External Engagement

  • Represent RTI‑HS through conference presentations, publications, workshops and webinars.
  • Build the external scientific profile of the ESS capability through active engagement with the research and HTA community including JCA.
  • Contribute to the advancement of evidence synthesis methodologies, promoting innovative approaches that leverage AI, automation, advanced analytics, and other emerging technologies where appropriate.
  • Support development of internal best practices, methodological guidance and reusable intellectual capital.

What You’ll Need

  • Advanced degree (PhD, DrPH, ScD, MD, PharmD, or equivalent) in epidemiology, health economics, biostatistics, public health, pharmacy, or a related scientific discipline, plus a minimum of 12+ years of relevant experience.
  • Significant relevant experience leading evidence synthesis activities within a pharmaceutical company, CRO, consulting organisation, or academic research environment.
  • Deep expertise in network meta-analysis, other indirect treatment comparison methods, advanced statistical methods, and broader evidence generation strategy.
  • Demonstrated success leading multidisciplinary project teams and managing complex client engagements.
  • Proven business development experience, including proposal leadership, client relationship management and revenue generation.
  • Strong expertise across advanced statistical and evidence synthesis methodologies, including Bayesian approaches, network meta-analysis, other indirect treatment comparisons, survival analysis and health utility analysis.
  • Familiarity with emerging methods and approaches, such as target trial emulation and evolving evidence synthesis techniques.
  • Advanced programming skills in R and/or STATA.
  • Strong understanding of global HTA, payer, and evolving JCA evidence requirements, and the role of evidence synthesis across the product lifecycle.
  • Exceptional communication and presentation skills, with the ability to engage scientific, commercial and executive audiences.

Executive Director, Evidence Synthesis & Statistics in Manchester employer: RTI International

RTI Health Solutions is an exceptional employer that fosters a collaborative and innovative work culture, where multidisciplinary teams thrive on delivering high-quality evidence solutions for global health challenges. With a strong commitment to employee growth, RTI-HS offers ample opportunities for professional development, mentorship, and leadership in the rapidly evolving field of health economics and outcomes research. Located in a vibrant area, employees benefit from a supportive environment that encourages scientific advancement and engagement with the broader research community.

RTI International

Contact Details:

RTI International Recruitment Team

We think you need these skills to ace Executive Director, Evidence Synthesis & Statistics in Manchester

Evidence Synthesis
Statistical Analysis
Bayesian Methods
Causal Inference
Patient-Reported Outcomes Analysis
Survival Analysis
Mixed Effects/Hierarchical Modeling