Director, Clinical Pharmacology
Director, Clinical Pharmacology

Director, Clinical Pharmacology

Full-Time 72000 - 108000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead innovative clinical pharmacology strategies to improve patient lives in rare diseases and oncology.
  • Company: Join a passionate team at Recursion, dedicated to transforming drug development.
  • Benefits: Competitive salary, health benefits, and opportunities for professional growth.
  • Why this job: Make a real impact on patients' lives while advancing your career in a dynamic environment.
  • Qualifications: Ph.D. or M.D. with clinical pharmacology expertise and 5-9+ years in biotech/pharmaceutical development.
  • Other info: Collaborative culture with excellent career advancement opportunities.

The predicted salary is between 72000 - 108000 £ per year.

Your work will change lives. Including your own.

The Impact You’ll Make

You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs.

In this role, you will:

  • Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan.
  • Be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster.
  • Design clinical studies and provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies.
  • Author and review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions.
  • Act as the clinical pharmacology expert during interactions with health authorities.
  • Interface with cross-functional teams, working closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams, and due diligence teams to ensure clinical pharmacology-related considerations are addressed.
  • Solve drug development questions/problems by overseeing and/or performing modeling and simulation with various tools to expedite decision making.

The Team You’ll Join

You will join the Development Sciences team within Recursion comprising clinical pharmacology, pharmacometrics, translational modeling, and clinical biomarkers. The Development Sciences group sits within Recursion’s Clinical Development organization. Team members get to sit on both Discovery and Development projects and work in a seamless end-to-end environment at Recursion. The team collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as well as discovery functions (DMPK, Biology, Chemistry, and Translational Biomarkers).

The Experience You’ll Need

Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship, with 5-9+ years of experience in biotech/pharmaceutical drug development. Demonstrated success leading all clinical pharmacology related aspects of drug development. Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response, and exposure-safety analyses through various phases of drug development. Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software. Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders. Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions, and attending regulatory meetings. Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company. Experience in oncology is preferred, but not an absolute requirement.

Director, Clinical Pharmacology employer: Recursion

At Recursion, we are committed to transforming the lives of patients through innovative drug development, and as a Director of Clinical Pharmacology, you will play a pivotal role in this mission. Our collaborative work culture fosters creativity and growth, providing ample opportunities for professional development while working alongside passionate experts in a dynamic environment. Located in a vibrant area, our team enjoys a supportive atmosphere that encourages innovation and the pursuit of excellence in tackling some of the most challenging diseases.
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Contact Detail:

Recursion Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Director, Clinical Pharmacology

✨Tip Number 1

Network like a pro! Reach out to your connections in the industry, attend relevant events, and engage with professionals on platforms like LinkedIn. We all know that sometimes it’s not just what you know, but who you know that can help you land that dream job.

✨Tip Number 2

Prepare for interviews by researching the company and its projects. Understand their clinical programs and be ready to discuss how your experience aligns with their goals. We want you to shine, so practice common interview questions and have your own questions ready to show your interest!

✨Tip Number 3

Showcase your expertise! Bring along examples of your past work, especially any innovative strategies you've implemented in clinical pharmacology. We love seeing how you’ve made an impact in previous roles, so don’t hold back on sharing your successes.

✨Tip Number 4

Apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team and making a difference in patients' lives.

We think you need these skills to ace Director, Clinical Pharmacology

Clinical Pharmacology
Pharmacometrics
Regulatory Submissions
Clinical Study Design
Modeling and Simulation
Pharmacokinetics
Pharmaceutical Sciences
Stakeholder Management
WinNonlin
Monolix
NONMEM
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Collaboration Skills
Problem-Solving Skills
Results-Oriented

Some tips for your application 🫡

Tailor Your CV: Make sure your CV reflects the specific skills and experiences that align with the Director, Clinical Pharmacology role. Highlight your expertise in clinical pharmacology and any relevant projects you've led to show us you're the perfect fit.

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to tell us why you're passionate about improving patient lives and how your background in drug development makes you an ideal candidate for this position. Be genuine and let your personality come through!

Showcase Your Achievements: When detailing your experience, focus on specific achievements that demonstrate your success in leading clinical pharmacology efforts. Use metrics or examples to illustrate how you've made an impact in previous roles—this will help us see your potential.

Apply Through Our Website: We encourage you to apply directly through our website. This ensures your application gets to the right people quickly and allows us to keep track of all applicants efficiently. Plus, it’s super easy to do!

How to prepare for a job interview at Recursion

✨Know Your Stuff

Make sure you brush up on your clinical pharmacology and pharmacometrics knowledge. Be ready to discuss specific strategies you've developed in past roles, especially those related to rare diseases and oncology. This will show that you’re not just familiar with the concepts but have practical experience applying them.

✨Showcase Your Collaboration Skills

Since this role involves working closely with various teams, be prepared to share examples of how you've successfully collaborated with cross-functional teams in the past. Highlight any experiences where you resolved conflicts or influenced stakeholders to achieve a common goal.

✨Prepare for Regulatory Questions

Expect questions about your experience with regulatory submissions and interactions. Think of specific instances where you’ve responded to agency questions or prepared clinical pharmacology sections for documents like INDs or NDAs. This will demonstrate your expertise and readiness for the role.

✨Be Innovative

The job description emphasises proposing innovative strategies. Come prepared with ideas on how you would approach drug development challenges. Discuss any modelling and simulation tools you’ve used and how they can expedite decision-making in clinical studies.

Director, Clinical Pharmacology
Recursion

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