At a Glance
- Tasks: Lead innovative clinical pharmacology strategies for rare disease and oncology programs.
- Company: Join Recursion, a pioneering TechBio company transforming drug discovery.
- Benefits: Flexible remote work, competitive salary, and opportunities for professional growth.
- Other info: Collaborative team environment with a focus on innovation and impact.
- Why this job: Make a real difference in patients' lives through cutting-edge drug development.
- Qualifications: Ph.D. or M.D. with extensive experience in clinical pharmacology and drug development.
The predicted salary is between 80000 - 100000 £ per year.
You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs.
In this role, you will:
- Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan.
- Be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster.
- Design clinical studies and provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies.
- Author and review relevant clinical pharmacology sections for regulatory documents, including Investigator's Brochures (IB), INDs, NDAs, and other regulatory submissions.
- Act as the clinical pharmacology expert during interactions with health authorities.
- Interface with cross-functional teams, working closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams, and due diligence teams to ensure clinical pharmacology-related considerations are addressed.
- Solve drug development questions/problems by overseeing and/or performing modeling and simulation with various tools to expedite decision making.
You will join the Development Sciences team within Recursion comprising clinical pharmacology, pharmacometrics, translational modeling, and clinical biomarkers. The Development Sciences group sits within Recursion’s Clinical Development organization. Team members get to sit on both Discovery and Development projects and work in a seamless end-to-end environment at Recursion. The team collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as well as discovery functions (DMPK, Biology, Chemistry, and Translational Biomarkers).
The Experience You’ll Need:
- Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D. with a Clinical Pharmacology fellowship, with 5-9+ years of experience in biotech/pharmaceutical drug development.
- Demonstrated success leading all clinical pharmacology related aspects of drug development.
- Ability to work closely with internal and external stakeholders to manage PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations to support dose selection, exposure-response, and exposure-safety analyses through various phases of drug development.
- Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software.
- Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders.
- Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions, and attending regulatory meetings.
- Highly motivated, decisive, and results-oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company.
- Experience in oncology is preferred, but not an absolute requirement.
Working Location & Compensation: Making SLC or NYC your home base is ideal; however, we will consider remote work for this position. We ask that remote employees commit to regular on-site visits for routine work and departmental events.
Recursion (NASDAQ: RXRX) is a clinical-stage TechBio company decoding biology to radically improve lives. Recursion is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need. Enabling its mission is the Recursion OS, an AI-native, end-to-end drug discovery and development platform integrating biology, chemistry, and clinical development into a unified intelligence system. Recursion is an Equal Opportunity Employer.
Clinical Pharmacology Lead - Rare Disease & Oncology Remote employer: Recursion
Recursion is an exceptional employer that fosters a collaborative and innovative work culture, dedicated to improving patient lives through cutting-edge drug development. With a strong focus on employee growth, team members are encouraged to engage in both discovery and development projects, benefiting from a seamless end-to-end environment. The opportunity to work remotely while being part of a passionate team in either Salt Lake City or New York City adds unique advantages for those seeking meaningful and rewarding employment in the biotech sector.
StudySmarter Expert Advice🤫
We think this is how you could land Clinical Pharmacology Lead - Rare Disease & Oncology Remote
✨Tip Number 1
Network like a pro! Reach out to professionals in the clinical pharmacology field on LinkedIn or at industry events. A friendly chat can lead to opportunities that aren’t even advertised yet.
✨Tip Number 2
Prepare for interviews by brushing up on your knowledge of drug development processes and regulatory interactions. We want you to showcase your expertise and passion for improving patient lives!
✨Tip Number 3
Don’t just apply anywhere; focus on companies that align with your values and interests, like Recursion. Tailor your approach to show how you can contribute to their mission of decoding biology.
✨Tip Number 4
Follow up after interviews! A quick thank-you email can keep you top of mind and show your enthusiasm for the role. Plus, it’s a great chance to reiterate why you’re the perfect fit.
We think you need these skills to ace Clinical Pharmacology Lead - Rare Disease & Oncology Remote
Some tips for your application 🫡
Tailor Your Application:Make sure to customise your CV and cover letter for the Clinical Pharmacology Lead role. Highlight your experience in clinical pharmacology and any relevant projects you've led, especially in rare diseases or oncology. We want to see how your background aligns with our mission!
Showcase Your Skills:Don’t forget to mention your proficiency with modelling software like WinNonlin or NONMEM. We’re looking for someone who can hit the ground running, so let us know how your skills can contribute to our innovative strategies in drug development.
Be Clear and Concise:When writing your application, keep it clear and to the point. Use straightforward language to describe your achievements and experiences. We appreciate a well-structured application that makes it easy for us to see your qualifications at a glance.
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, you’ll get to explore more about our company and culture while you’re at it!
How to prepare for a job interview at Recursion
✨Know Your Stuff
Make sure you brush up on your clinical pharmacology knowledge, especially around rare diseases and oncology. Be ready to discuss specific strategies you've developed in the past and how they can apply to the role at Recursion.
✨Showcase Your Collaboration Skills
Since this role involves working with cross-functional teams, prepare examples of how you've successfully collaborated with different departments. Highlight any experiences where you resolved conflicts or influenced stakeholders to achieve results.
✨Be Ready for Regulatory Talk
Expect questions about your experience with regulatory submissions and interactions. Have specific examples ready that demonstrate your ability to respond to agency questions and prepare clinical pharmacology sections for documents like INDs and NDAs.
✨Demonstrate Your Problem-Solving Skills
Think of instances where you've tackled complex drug development questions using modelling and simulation tools. Be prepared to discuss the methodologies you used and how they expedited decision-making in your previous roles.
