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- Tasks: Lead the validation of TCR engagers for cancer immunotherapy development.
- Company: Join a pioneering biotech company revolutionising cancer treatment through innovative therapies.
- Benefits: Enjoy competitive pay, remote work flexibility, and a supportive team environment.
- Other info: Opportunity for career progression in a flat hierarchy where your contributions matter.
- Why this job: Be part of groundbreaking research with real-world impact in a collaborative culture.
- Qualifications: PhD in relevant fields with industry experience in bispecific or T-cell engager development required.
The predicted salary is between 48000 - 84000 £ per year.
Are you an ambitious scientist with a PhD and/or industry experience in bispecific or T-cell engager development, eager to accelerate novel cancer immunotherapies?
Join a pioneering biotechnology company at the forefront of engineering TCR engagers for immuno-oncology application. This role is critical to advancing novel therapeutic candidates rapidly towards clinical development, with an IND submission targeted within a year.
The client are seeking a dynamic Senior or Principal Scientist to lead crucial in vivo and in vitro validation of TCR engagers .
This role specifically requires bispecific or T-cell engager experience with IND-enabling processes .
Your technical responsibilities will span:
- TCR design and characterization .
- Protein science operations , including expression, purification, and biophysical analysis (e.g., SPR – experience preferred but not essential).
- Molecular biology duties such as cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing (emphasis on cloning and PCR preferred).
- Cellular and immunological assays (e.g., cell killing assays, flow cytometry, IncuCyte-based assays, ELISA).
- Tissue culture management .
- Experience with NGS analysis pipelines (specifically data analysis using R) is desired.
- Experience overseeing outsourced in vivo studies (without needing to have performed them yourself) is a plus.
You\’ll thrive in a flat hierarchy where everyone contributes hands-on. This is a fantastic opportunity for career progression, offering a highly collaborative and supportive cross-disciplinary environment. The client offers very competitive compensation, with flexibility for remote work as project demands allow.
If you hold a PhD in Immunology, Cell Biology, Biochemistry, or a related field with 1-2+ years (Senior) or 3+ years (Principal) of relevant industry experience, and possess critical experience with bispecific or TCR engager validation towards IND, apply now to learn more about this impactful role!
Senior / Principal Scientist employer: RBW Consulting
Contact Detail:
RBW Consulting Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior / Principal Scientist
✨Tip Number 1
Network with professionals in the biotechnology and immuno-oncology fields. Attend relevant conferences, webinars, or workshops to meet potential colleagues and learn about the latest advancements. This can help you gain insights into the company culture and the specific skills they value.
✨Tip Number 2
Engage with the company's online presence. Follow them on social media platforms like LinkedIn and Twitter to stay updated on their projects and achievements. Commenting on their posts or sharing relevant content can help you get noticed by their team.
✨Tip Number 3
Prepare to discuss your hands-on experience with TCR engagers and bispecific antibodies in detail during interviews. Be ready to share specific examples of your work, including any challenges you faced and how you overcame them, as this will demonstrate your expertise and problem-solving skills.
✨Tip Number 4
Familiarise yourself with the IND-enabling processes and regulatory requirements in the biotech industry. Understanding these aspects will not only enhance your credibility but also show your commitment to advancing therapeutic candidates towards clinical development.
We think you need these skills to ace Senior / Principal Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in bispecific or T-cell engager development. Emphasise any specific projects or roles that align with the job description, particularly those involving IND-enabling processes.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for cancer immunotherapy and your technical expertise. Mention your PhD and any industry experience, and explain how your skills can contribute to the company's goals in advancing novel therapeutic candidates.
Highlight Technical Skills: In your application, clearly outline your technical skills related to TCR design, protein science operations, and molecular biology. Include any experience with cellular assays and NGS analysis pipelines, as these are crucial for the role.
Showcase Collaborative Experience: Since the company values a collaborative environment, include examples of past teamwork and cross-disciplinary projects. This will demonstrate your ability to thrive in a flat hierarchy and contribute effectively to the team.
How to prepare for a job interview at RBW Consulting
✨Showcase Your Technical Expertise
Be prepared to discuss your experience with bispecific or T-cell engagers in detail. Highlight specific projects where you contributed to TCR design, protein science operations, or molecular biology tasks. This will demonstrate your hands-on knowledge and suitability for the role.
✨Familiarise Yourself with IND Processes
Since the role involves advancing therapeutic candidates towards IND submission, make sure you understand the IND-enabling processes. Be ready to discuss how your previous work aligns with these requirements and any relevant experiences you've had in this area.
✨Prepare for Collaborative Scenarios
Given the flat hierarchy and collaborative environment, think of examples where you've successfully worked in teams. Be ready to share how you contribute to group dynamics and support cross-disciplinary efforts, as this is crucial for the company's culture.
✨Demonstrate Problem-Solving Skills
Expect questions that assess your problem-solving abilities, especially in relation to experimental challenges. Prepare to discuss specific instances where you overcame obstacles in your research or project work, particularly in cellular and immunological assays.