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- Tasks: Lead in vivo and in vitro validation of TCR engagers for cancer immunotherapy.
- Company: Join a pioneering biotech company revolutionising cancer treatment through innovative TCR engineering.
- Benefits: Enjoy competitive pay, remote work flexibility, and a collaborative team environment.
- Why this job: Be part of groundbreaking research with real-world impact in a supportive, hands-on culture.
- Qualifications: PhD in relevant field with 1-3+ years industry experience in bispecific or TCR engager development.
- Other info: Opportunity for career progression in a flat hierarchy where every voice matters.
The predicted salary is between 43200 - 72000 £ per year.
Are you an ambitious scientist with a PhD and/or industry experience in bispecific or T-cell engager development, eager to accelerate novel cancer immunotherapies? Join a pioneering biotechnology company at the forefront of engineering TCR engagers for immuno-oncology application. This role is critical to advancing novel therapeutic candidates rapidly towards clinical development, with an IND submission targeted within a year.
The client is seeking a dynamic Senior or Principal Scientist to lead crucial in vivo and in vitro validation of TCR engagers. This role specifically requires bispecific or T-cell engager experience with IND-enabling processes.
Your technical responsibilities will span:
- TCR design and characterization
- Protein science operations, including expression, purification, and biophysical analysis (e.g., SPR - experience preferred but not essential)
- Molecular biology duties such as cloning, mutagenesis, DNA isolation, and preparing libraries for deep sequencing (emphasis on cloning and PCR preferred)
- Cellular and immunological assays (e.g., cell killing assays, flow cytometry, IncuCyte-based assays, ELISA)
- Tissue culture management
- Experience with NGS analysis pipelines (specifically data analysis using R) is desired
- Experience overseeing outsourced in vivo studies (without needing to have performed them yourself) is a plus
You’ll thrive in a flat hierarchy where everyone contributes hands-on. This is a fantastic opportunity for career progression, offering a highly collaborative and supportive cross-disciplinary environment. The client offers very competitive compensation, with flexibility for remote work as project demands allow.
If you hold a PhD in Immunology, Cell Biology, Biochemistry, or a related field with 1-2+ years (Senior) or 3+ years (Principal) of relevant industry experience, and possess critical experience with bispecific or TCR engager validation towards IND, apply now to learn more about this impactful role!
Senior / Principal Scientist employer: RBW Consulting
Contact Detail:
RBW Consulting Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior / Principal Scientist
✨Tip Number 1
Network with professionals in the biotechnology and immuno-oncology fields. Attend relevant conferences, webinars, or local meetups to connect with industry experts and learn about potential job openings at companies like us.
✨Tip Number 2
Engage with our company on social media platforms. Follow us on LinkedIn and Twitter to stay updated on our latest projects and job postings, and don’t hesitate to reach out to current employees for insights into our work culture.
✨Tip Number 3
Showcase your expertise in bispecific or T-cell engager development through online platforms. Consider writing articles or sharing your research on platforms like ResearchGate or LinkedIn to demonstrate your knowledge and passion for the field.
✨Tip Number 4
Prepare for potential interviews by brushing up on the latest advancements in cancer immunotherapy and TCR engineering. Familiarise yourself with our recent publications and projects to discuss how your experience aligns with our goals during the interview process.
We think you need these skills to ace Senior / Principal Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in bispecific or T-cell engager development. Emphasise any specific projects or roles that align with the job description, particularly those involving IND-enabling processes.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for cancer immunotherapy and your specific expertise in TCR engagers. Mention how your background aligns with the company's goals and how you can contribute to their mission.
Highlight Technical Skills: In your application, clearly outline your technical skills related to protein science operations, molecular biology, and cellular assays. If you have experience with NGS analysis pipelines or overseeing outsourced studies, make sure to include that as well.
Showcase Collaborative Experience: Since the role emphasises a collaborative environment, provide examples of past experiences where you worked effectively in teams. Highlight your ability to contribute hands-on and thrive in a flat hierarchy.
How to prepare for a job interview at RBW Consulting
✨Showcase Your Technical Expertise
Be prepared to discuss your experience with bispecific or T-cell engagers in detail. Highlight specific projects where you contributed to TCR design, protein science operations, or molecular biology tasks. This will demonstrate your hands-on knowledge and suitability for the role.
✨Familiarise Yourself with IND Processes
Since the role involves advancing therapeutic candidates towards IND submission, make sure you understand the IND-enabling processes. Be ready to discuss how your previous work aligns with these requirements and any relevant experiences you've had in this area.
✨Prepare for Collaborative Scenarios
Given the emphasis on a collaborative environment, think of examples where you've successfully worked in cross-disciplinary teams. Be ready to share how you contributed to team success and how you handle feedback and differing opinions.
✨Demonstrate Your Problem-Solving Skills
In the fast-paced world of biotechnology, problem-solving is key. Prepare to discuss challenges you've faced in your research and how you overcame them. This will show your ability to think critically and adapt in a dynamic setting.
