At a Glance
- Tasks: Lead strategic modelling for drug development and influence key decisions across projects.
- Company: Global biopharma company focused on innovative drug development.
- Benefits: Competitive salary, professional growth, and the chance to shape future therapies.
- Other info: Collaborative environment with opportunities to coach and develop team members.
- Why this job: Make a real impact in biopharma with your expertise in modelling and simulation.
- Qualifications: PhD in relevant field and 5+ years of PBPK/QSP experience required.
The predicted salary is between 72000 - 108000 £ per year.
I’m working with a global biopharma company seeking an accomplished PBPK Lead to strengthen their Quantitative Clinical Pharmacology (QCP) function. This is a strategic scientific leadership role for someone who wants to shape modelling strategy and influence decision‑making across an exciting development pipeline. The successful candidate will take ownership of the end‑to‑end Pharmacometrics strategy, ensuring that modelling insights directly guide project direction and development milestones.
Key aspects of the role include:
- Setting the strategic direction for model‑informed drug development, driving decisions around dose selection, extrapolation, study design and paediatric planning.
- Delivering hands‑on PBPK, QSP and clinical simulation work across multiple assets.
- Converting complex model outputs into clear scientific recommendations for cross‑functional teams and senior stakeholders.
- Producing high‑quality, regulatory‑appropriate analysis plans, reports and documentation.
- Managing external vendors and supporting the build‑out of internal PMx capability.
- Coaching team members and championing state‑of‑the‑art mechanistic modelling approaches.
My client is looking for someone with:
- A PhD in Pharmaceutical Sciences, Engineering, Statistics or a related modelling discipline.
- 5+ years of PBPK and QSP experience in the biotech/pharma sector.
- Strong practical skills in PK‑Sim®/MoBi®, SimCyp®, GastroPlus®, Matlab and R.
- Clear, confident communication skills and the ability to influence across multidisciplinary groups.
Director, PBPK & QSP Modelling and Simulation in London employer: RBW Consulting
RBW Consulting is an excellent employer, offering a dynamic work environment in West Cheshire that fosters innovation and collaboration. Employees benefit from a strong focus on professional development, with opportunities for growth and skill enhancement in the fast-paced engineering sector. The company values its team members, providing a supportive culture that encourages work-life balance and rewards dedication.
StudySmarter Expert Advice🤫
We think this is how you could land Director, PBPK & QSP Modelling and Simulation in London
✨Tip Number 1
Network like a pro! Reach out to professionals in the biopharma industry on LinkedIn or at conferences. We can’t stress enough how important it is to make connections that could lead to job opportunities.
✨Tip Number 2
Prepare for interviews by practising your storytelling skills. We want you to showcase your PBPK and QSP experience in a way that highlights your strategic thinking and problem-solving abilities. Make sure you can explain complex concepts clearly!
✨Tip Number 3
Don’t just apply anywhere; focus on companies that align with your values and career goals. We recommend checking out our website for tailored job listings that match your expertise in modelling and simulation.
✨Tip Number 4
Follow up after interviews! A simple thank-you email can go a long way. We suggest reiterating your enthusiasm for the role and briefly mentioning how your skills can contribute to their modelling strategy.
We think you need these skills to ace Director, PBPK & QSP Modelling and Simulation in London
Some tips for your application 🫡
Tailor Your CV:Make sure your CV reflects the specific skills and experiences that align with the PBPK and QSP modelling role. Highlight your PhD and relevant experience in the biotech/pharma sector to catch our eye!
Craft a Compelling Cover Letter:Use your cover letter to tell us why you're the perfect fit for this strategic leadership role. Share your passion for model-informed drug development and how you can influence decision-making in our exciting pipeline.
Showcase Your Technical Skills:Don’t forget to mention your hands-on experience with tools like PK-Sim®, SimCyp®, and Matlab. We want to see how your practical skills can contribute to our team and projects!
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for this fantastic opportunity!
How to prepare for a job interview at RBW Consulting
✨Know Your Modelling Inside Out
Make sure you’re well-versed in PBPK and QSP modelling techniques. Brush up on your practical skills with tools like PK-Sim, SimCyp, and R. Be ready to discuss specific projects where you've applied these methods and how they influenced decision-making.
✨Showcase Your Strategic Thinking
Prepare to talk about how you've set strategic directions in past roles. Think of examples where your modelling insights shaped drug development decisions, especially around dose selection and study design. This will demonstrate your ability to lead and influence.
✨Communicate Clearly and Confidently
Practice explaining complex modelling outputs in simple terms. You’ll need to convey your findings to cross-functional teams and senior stakeholders, so focus on clarity and confidence in your communication style.
✨Highlight Your Leadership Skills
Be ready to discuss your experience in coaching team members and managing external vendors. Share examples of how you've championed innovative modelling approaches and built internal capabilities, as this is key for a strategic leadership role.
