At a Glance
- Tasks: Lead advanced gene editing and stem cell research projects at a cutting-edge biomedical institute.
- Company: Join the Francis Crick Institute, Europe's largest biomedical research hub.
- Benefits: Competitive salary from £47,080, plus benefits and professional development opportunities.
- Other info: Dynamic environment fostering collaboration and creativity in scientific exploration.
- Why this job: Make a real impact in innovative research that advances human health.
- Qualifications: PhD or MSc with extensive experience in gene editing and stem cell biology.
The predicted salary is between 47080 - 47080 £ per year.
Salary for this Role: From £47,080 with benefits, subject to skills and experience.
Contract term: This is a full-time permanent position on Crick terms and conditions of employment.
About us
The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
About the Stem Cells and Organoid Platform (SCOP)
The Stem Cells and Organoids Platform (SCOP) at the Francis Crick Institute is a Science Technology Platform (STP) dedicated to advancing innovative research in human stem cell biology and organoid technologies. It provides specialised expertise and services that support the development of human model systems.
About the role
We are seeking a highly skilled and motivated Senior Laboratory Research Scientist (SLRS) to lead and support advanced gene editing and stem cell research within SCOP. The successful candidate will play a key role in designing and implementing cutting-edge genome engineering strategies, and driving innovation across diverse research and service projects.
What you'll be doing
- Leading and delivering SCOP research and service projects, owning scientific direction and outcomes.
- Designing and implementing advanced gene editing strategies tailored to project needs.
- Working closely with GeMS and STPs to develop robust, innovative genome engineering solutions.
- Establishing shared methods and technologies with group leaders, strengthening institute capability.
- Staying at the forefront of CRISPR technologies through active horizon scanning and engagement.
- Training and mentoring researchers in gene editing and stem cell culture best practice.
- Engineering and maintaining high-quality iPSC and ESC lines, ensuring reproducibility and QC.
- Supporting effective lab operations, including SOPs, biosafety, resources and equipment.
- Communicating clearly across teams, contributing to reports, collaboration and supportive research culture.
- Participating in a weekend rota for stem cell maintenance.
About you
You will have:
- Essential: Higher degree in a relevant field (PhD, MSc) with three years of research experience.
- Extensive proficiency in designing and implementing gene editing strategies in human pluripotent stem cells, including generation of knockout, knock-in, or conditional alleles.
- Extensive proficiency in molecular biology techniques, including molecular cloning, DNA/RNA extraction, PCR, RT-qPCR, and sequencing.
- Strong background in stem cell biology, with hands-on experience in the culture and maintenance of human pluripotent stem cells (iPSCs and/or ESCs).
- Experience using bioinformatics tools for guide RNA design, off-target prediction, and genomic data analysis.
- Experience and familiarity with base- and prime-editing approaches.
- Experience in experimental design, troubleshooting, and data analysis.
- Excellent attention to detail and commitment to maintaining high standards of data quality, documentation, and reproducibility.
- Proven ability to manage multiple projects simultaneously and deliver results within agreed timelines.
Senior Laboratory Research Scientist - Gene Editing employer: PVH (Tommy Hilfiger/Calvin Klein)
Intapp is an exceptional employer, offering a dynamic work environment that fosters innovation and collaboration within the accounting and consulting sectors across EMEA. With a strong commitment to employee growth, Intapp provides ample opportunities for professional development and leadership coaching, ensuring that team members thrive in their careers while contributing to the company's strategic vision. The culture is built on accountability and high performance, making it an ideal place for those looking to make a significant impact in a rapidly evolving industry.
Contact Details:
PVH (Tommy Hilfiger/Calvin Klein) Recruitment Team
