At a Glance
- Tasks: Design and engineer innovative mRNA components for groundbreaking gene editing therapies.
- Company: Join Prime Medicine, a leader in next-gen gene editing technology.
- Benefits: Competitive salary, health benefits, equity programs, and generous paid time off.
- Other info: Collaborative environment with opportunities for rapid career growth and mentorship.
- Why this job: Make a real impact on patients' lives through cutting-edge scientific innovation.
- Qualifications: Ph.D. in relevant field with expertise in mRNA biology and engineering.
Company Overview: Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies.
Position Overview: We are seeking an exceptionally driven, discovery-minded Senior Scientist to join our Platform Technology & Innovation team. This team sits at the very heart of Prime Medicine's innovation engine, reflecting our commitment to accelerating the next frontier of Prime Editing science. Its mission is to invent, establish, and rapidly implement the platform technologies that will define what new capabilities Prime Editing can achieve, and ultimately, what cures become possible for patients.
Primary Responsibilities:
- Design, construct, and systematically optimize novel mRNA architectures for Prime Editing applications.
- Design and execute well-controlled experiments to probe structure-function relationships in Prime Editing system components.
- Lead discovery efforts for novel therapeutic approaches and platform-level applications enabled by Prime Editing.
- Partner with cross-functional teams and external collaborators to translate platform advances into program-specific solutions.
- Maintain active engagement with the scientific literature and emerging technologies in mRNA engineering.
- Communicate research findings clearly to internal scientific audiences; contribute to publications, patent filings, and conference presentations.
- Adhere to all laboratory safety requirements and procedures; author, review, and maintain accurate laboratory notebooks.
- Mentor and provide day-to-day scientific direction to research associates and interns/co-op students.
Preferred Qualifications:
- Ph.D. in Molecular Biology, Biochemistry, RNA Biology, Chemical Biology, or a closely related field, plus 5+ years of relevant postdoctoral and/or drug discovery research experience.
- Deep hands-on expertise in mRNA biology and engineering.
- Experience working in a collaborative, cross-functional research environment.
- Familiarity with CRISPR-based or other precision gene editing technologies.
- Excellent scientific communication skills, with the ability to present complex findings clearly to diverse audiences.
This position in the Platform Technology & Innovation team is a rare opportunity to join a small, world-class team doing foundational science with direct and rapid translation to impact patients.
Senior Scientist, mRNA Design & Platform Innovation in Cambridge employer: Prime Medicine
Prime Medicine is an exceptional employer that fosters a culture of innovation and collaboration, making it an ideal place for scientists passionate about advancing gene editing therapies. Located in a dynamic biotechnology hub, employees benefit from robust health and wellness programs, generous paid time off, and opportunities for professional growth within a world-class team dedicated to impactful research. The hands-on nature of the Senior Scientist role allows for direct contributions to groundbreaking science, ensuring that discoveries translate swiftly into real-world patient benefits.
