At a Glance
- Tasks: Lead DMPK strategy and drive scientific excellence in drug discovery projects.
- Company: Join Pharmaron, a global leader in integrated drug discovery services.
- Benefits: Competitive salary, collaborative environment, and opportunities for innovation.
- Other info: Be part of a dynamic team focused on cutting-edge multi-modality programmes.
- Why this job: Shape the future of drug discovery and influence strategy at a senior level.
- Qualifications: PhD and 15+ years in DMPK leadership with a proven track record.
The predicted salary is between 81000 - 99000 £ per year.
Pharmaron is seeking an exceptional Head of DMPK, Drug Discovery to lead and evolve our DMPK capability within the Integrated Drug Discovery (IDD) Services group. The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing.
Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic. This is a high-impact leadership role at the forefront of multi-modality drug discovery, where you will shape strategy, drive scientific excellence, and deliver client programmes from target identification through to IND. Working across a global, AI-enabled platform, you’ll help accelerate innovative medicines towards the clinic.
The Opportunity
- Define and deliver the DMPK vision and strategy aligned to Pharmaron’s global drug discovery ambitions
- Provide expert DMPK, ADME and PK/PD leadership across a diverse portfolio of client programmes
- Lead and grow a high-performing team of DMPK scientists, ensuring capability across small molecules and other modalities (e.g. degraders, ADCs, peptides)
- Play a critical role in integrated projects, driving decision-making and delivering clear milestones from hit finding to IND
- Represent Pharmaron externally, building strong client partnerships and scientific reputation
- Contribute to the adoption of AI and computational tools to enhance Design–Make–Test–Analyse cycles
- Develop new scientific capabilities and commercial offerings, strengthening Pharmaron’s position as a leading CRO partner
Key Responsibilities
- Lead DMPK strategy across integrated drug discovery projects
- Manage team performance, resourcing and hiring to support growth
- Deliver scientific leadership on client programmes with a focus on quality, speed and probability of success
- Drive cross-functional collaboration across modelling, in vitro ADME, in vivo PK, pharmacology, formulation development, clinical teams
- Contribute to proposal development and business growth
- Act as a senior voice within global Pharmaron DMPK leadership
About You
- PhD (or equivalent experience) in a relevant discipline
- 15+ years’ experience in a DMPK leadership role within drug discovery
- Proven track record of progressing compounds through preclinical milestones
- Experience of working across multiple modalities beyond traditional small molecules for example degraders, peptides, ADCs, antibodies
- Strong leadership experience in matrixed, multi-disciplinary environments
Knowledge & Skills
- Deep expertise in DMPK, PK/PD and translational science
- Track record of implementing drug discovery strategy and new technologies
- Familiarity and have a passion for computational/AI approaches in drug discovery
- Excellent stakeholder management and client-facing capability
Leadership Attributes
- Strategic thinker with strong commercial awareness
- Clear, confident decision-maker with high scientific credibility and strong publication record
- Collaborative and influential across global teams
- Enthusiastic about innovation, talent development and scientific excellence
Why Join Pharmaron?
- Be part of a global, industry leading integrated drug discovery organisation with ability to shape future scientific and business direction
- Work on cutting-edge multi-modality programmes
- Influence strategy, science and growth at a senior leadership level
- Join a collaborative environment focused on innovation, quality and impact
If you’re a DMPK leader ready to shape the future of drug discovery in a fast-growing, global CRO environment, we’d love to hear from you.
Senior Director, Head of DMPK, Drug Discovery Services in Hoddesdon employer: Pharmaron Biologics
Pharmaron is an exceptional employer, offering a dynamic work environment in Cardiff where you can thrive as a Quality and EHS Advisor. With a strong focus on employee development, our supportive Compliance team encourages growth through diverse responsibilities in quality assurance and environmental health and safety. Join us to make a meaningful impact in the pharmaceutical industry while enjoying competitive benefits and a collaborative culture that values your contributions.
