At a Glance
- Tasks: Lead DMPK activities and guide drug discovery projects with cutting-edge science.
- Company: Join Pharmaron, a leading global R&D service company in life sciences.
- Benefits: Competitive salary, career development, and access to state-of-the-art facilities.
- Other info: Dynamic environment with opportunities for growth and collaboration across global teams.
- Why this job: Make a real impact on innovative medicines and collaborate with top scientists.
- Qualifications: PhD or equivalent in pharmacology or related field with DMPK experience.
The predicted salary is between 60000 - 70000 £ per year.
Pharmaron is seeking an experienced Associate Principal Scientist, DMPK to join our Integrated Drug Discovery team in Hoddesdon. The Integrated Drug Discovery (IDD) Services group at Pharmaron is responsible for leading and delivering drug discovery projects for our client partners. The team comprises scientific expertise and strategic leadership across medicinal chemistry, CADD, biology, DMPK and translational science. Combined with Pharmaron’s global research capabilities we design and deliver integrated programmes from target identification and hit finding through to IND filing. Working closely with our partners we define strategy, coordinate execution across teams and with an AI enabled accelerated Design–Make–Test–Analyse cycles support the progression of projects and innovative medicines towards the clinic.
This is an exciting opportunity for an experienced DMPK scientist to provide scientific leadership across a diverse portfolio of discovery programmes. You will apply your expertise in DMPK, ADME, pharmacokinetics and translational science to guide project strategy, interpret complex datasets and support informed decision-making.
About Pharmaron: Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has established a broad range of drug research and development capabilities spanning synthetic, medicinal and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry, metabolism, chemical and pharmaceutical development, and clinical development.
Our Drug Discovery department in Hoddesdon provides scientific leadership to partners across the life sciences industry. Working in collaboration with Pharmaron’s global capabilities and resources, the multidisciplinary team delivers high-quality small-molecule preclinical candidates across a range of therapeutic areas and routes of administration.
The Opportunity: You will:
- Provide scientific leadership across integrated DMPK, ADME and PK activities.
- Develop fit-for-purpose study and screening strategies for small-molecule discovery programmes.
- Interpret and integrate in vitro ADME, in vivo PK and multidisciplinary project data.
- Conduct IVIVE, human PK and dose predictions, using state of the art techniques.
- Translate complex DMPK data into clear recommendations that support project decisions.
- Troubleshoot scientific and technical issues relating to DMPK and ADME studies.
- Prepare and present high-quality reports, data summaries and scientific recommendations.
- Act as a scientific point of contact for clients and multidisciplinary project teams.
- Coordinate DMPK activities across our global organisation to support timely and effective project delivery.
About You: Qualifications and Experience: You will have:
- A BSc, MSc, PhD or equivalent experience in pharmacology, pharmaceutical sciences or a related discipline.
- Significant experience supporting DMPK drug discovery or development programmes.
- Strong knowledge of in vitro ADME and in vivo PK principles, assays and how physicochemical properties impact these properties.
- Experience designing studies and interpreting complex PK and ADME datasets.
- Knowledge of IVIVE, human PK prediction and dose prediction methodologies.
- Familiarity with PBPK modelling approaches and relevant software is an advantage.
- Experience applying DMPK science to small-molecule discovery programmes with experience with other modalities an advantage.
- Experience working within multidisciplinary drug discovery teams.
- Previous pharmaceutical, biotechnology or CRO experience.
Professional Attributes: You will be:
- Confident in providing scientific direction and technical recommendations.
- Able to communicate complex findings clearly to scientific teams and clients.
- Collaborative, client-focused and comfortable working across global teams.
- Organised and able to manage priorities across multiple projects.
- Proactive in identifying scientific challenges and developing practical solutions.
- Committed to scientific quality, continuous improvement and knowledge sharing.
Why Join Pharmaron? Join a global, industry-leading drug discovery organisation. Contribute to drug discovery programmes from hit finding through to candidate nomination and IND. Collaborate with specialists across medicinal chemistry, biology, pharmacology, DMPK and translational science. Access Pharmaron’s global scientific capabilities and research platforms. Work in a state-of-the-art scientific environment at our Hoddesdon site. Develop your career within a collaborative and growing organisation.
If you are an experienced DMPK scientist who is passionate about applying PK and ADME science to integrated drug discovery, we would love to hear from you. Join Pharmaron and help progress innovative medicines towards the clinic.
Associate Principal Scientist, DMPK employer: Pharmaron Biologics
Pharmaron is an exceptional employer, offering a dynamic and collaborative work environment where you can make a significant impact in the pharmaceutical industry. As the Head of Partnerships, you'll have the opportunity to shape strategic relationships with leading global clients while benefiting from competitive salaries, comprehensive benefits, and robust employee growth opportunities within a fast-growing organisation. Join us in driving innovation and delivering high-quality services that support the development of life-changing therapies.
StudySmarter Expert Advice🤫
We think this is how you could land Associate Principal Scientist, DMPK
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We think you need these skills to ace Associate Principal Scientist, DMPK
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Pharmaron Biologics!
Emphasise Your Understanding of Regulations:The pharmaceutical industry is heavily regulated, so it's important to indicate your familiarity with industry standards and regulations. In your cover letter, mention any training or certifications you've received that are relevant, or discuss projects where you’ve navigated compliance. This will show Pharmaron Biologics that you're not just a fit for the job but also a safety-conscious candidate!
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How to prepare for a job interview at Pharmaron Biologics
✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Pharmaron Biologics that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
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If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
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In a full-time pharmaceutical role, understanding the regulatory landscape is crucial. Prepare for situational questions that may test your problem-solving skills concerning compliance and safety standards. You could be asked how you'd handle a hypothetical issue regarding a drug’s market release, so think through your approach.
