Postdoctoral Research Associate in Oxford

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We’re looking for a Postdoctoral Research Associate to join the Sanders and Rinaldi Groups at the University of Oxford. This is an exciting opportunity to contribute to cutting‑edge research in gene regulation and neurodevelopment, working within the Institute of Developmental & Regenerative Medicine (IDRM) and the Department of Paediatrics.

Location: Sanders Research Group, Institute of Developmental and Regenerative Medicine (IDRM), Old Road Campus, Oxford

Contract type: Full‑time, fixed‑term for 3 years

About the Role

Join the University of Oxford at an exceptional moment as we expand the scientific impact of the Sanders and Rinaldi research groups—internationally recognised teams advancing understanding of rare genetic disorders and accelerated therapeutic development. This position also forms part of the MRC Centre of Research Excellence (CoRE) in Therapeutics Genomics, one of the UK’s flagship initiatives to transform genome‑targeted therapies.

As Postdoctoral Research Associate, you will lead computational research focused on splicing dynamics in the developing human brain, investigating how disruptions contribute to neurodevelopmental and neurological disorders. You will work with large‑scale genomic data (including short‑ and long‑read RNA‑seq, ATAC‑seq, and whole genome sequencing) to uncover mechanisms of disease and identify potential routes to therapeutic intervention.

In this dynamic and multidisciplinary role, you will collaborate closely with senior academics, clinical partners, and researchers across Oxford and international institutions. You will develop and run complex analysis pipelines, generate insights that contribute to high‑impact publications, support junior researchers, and help shape future research directions within the programme.

About You

You will hold (or be near completion of) a PhD/DPhil in genetics, computational biology, biostatistics, or a related discipline, with strong experience analysing genomic data. You will bring proficiency in programming (e.g., Python, R) and demonstrable expertise in processing and interpreting large‑scale functional genomic datasets.

You will be a driven and collaborative scientist with excellent communication skills, capable of managing your own research projects, contributing to interdisciplinary discussions, and presenting your work to diverse audiences. Experience working with splicing analysis, long‑read sequencing, or neurodevelopmental biology will be advantageous but not essential. Above all, you will be enthusiastic about making meaningful contributions to understanding and treating genetic disease.

About Us

The Department of Paediatrics at the University of Oxford is a vibrant and inclusive community at the forefront of child health research and clinical care. Our academics and clinicians work side by side to translate world‑leading scientific discoveries into real benefits for children and families locally, nationally, and globally.

We hold the Athena Swan Gold Award, recognising our commitment to equality, inclusivity, and staff development. Alongside a welcoming culture rooted in wellbeing, we offer opportunities for personal growth, collaboration, and meaningful impact.

As part of the Medical Sciences Division, you will join one of the world’s leading environments for biomedical and clinical research, with state‑of‑the‑art facilities and a strong culture of innovation and excellence.

What We Offer

Working at the University of Oxford offers several exclusive benefits, such as:

• 38 days of annual leave (inclusive of public holidays) to support your wellbeing, with the option to purchase up to 10 extra days.
• One of the most generous family leave schemes in UK higher education, offering up to 26 weeks of full-pay maternity and adoption leave, plus 12 weeks of full-pay paternity/partner leave.
• A commitment to hybrid and flexible working to suit your lifestyle.
• Affordable and sustainable commuting options, including a cycle loan scheme, discounted bus travel, and season ticket loans.
• Access to a vibrant community through our social, cultural, and sports clubs.

The closing date for applications is 12:00pm (GMT) on 19 December 2025.

You can view more details by clicking the ‘Apply’ button.

Seniority level

Associate

Employment type

Full‑time

Job function

Research – Higher Education and Research Services

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