Research Scientist - Oligonucleotide Synthesis

Research Scientist - Oligonucleotide Synthesis

Full-Time 28800 - 48000 £ / year (est.) No working from home possible
Oxford Nanopore Technologies

At a Glance

  • Tasks: Join our team to develop cutting-edge oligonucleotide synthesis methods and support innovative R&D projects.
  • Company: Oxford Nanopore Technologies, a leader in molecular analysis technology.
  • Benefits: Competitive salary, training opportunities, and a dynamic work environment.
  • Other info: Thriving culture of innovation with global reach and career growth potential.
  • Why this job: Make a real impact in biotechnology and contribute to groundbreaking research.
  • Qualifications: BSc, MSc or PhD in chemistry; experience in oligonucleotide synthesis preferred.

The predicted salary is between 28800 - 48000 £ per year.

Oligonucleotide Scientist - Oligonucleotide Synthesis Team

Location: Harwell, Oxfordshire

Work Model: Fully on-site

We are seeking a highly motivated Oligonucleotide Scientist to join our newly established Oligonucleotide Synthesis Team. This is an exciting and challenging role where you will assist in expanding our nucleotide and oligonucleotide synthesis capabilities aimed at research and development (R&D).

Depending on experience, the successful candidate will take on technical leadership roles and collaborate closely with other team members in the oligonucleotide facility. This role involves developing new synthesis, purification, and analytical methodologies/workflows for a wide range of critical long and modified DNA/RNA oligonucleotides. You will also play a collaborative role in the strategic decision-making that influences future projects for the team and the company.

Key Responsibilities
  • Developing an oligonucleotide synthesis pipeline to serve critical R&D projects.
  • Developing synthesis methodologies for complex, modified, and long DNA/RNA oligonucleotides.
  • Improving purification and analytical workflows for synthesized oligonucleotides, introducing automation where possible.
  • Analysing oligonucleotides by high-resolution CE, LC‑MS, and HPLC.
  • Onboarding new technology and methods to improve operational effectiveness.
  • Contributing to the scientific and technical training of the team.
  • Supporting ambitious and innovative R&D projects.
  • Preparing clearly articulated progress reports and keeping well‑organized experimental records.
  • Working and communicating effectively across several research and development groups.
  • Promoting a safe working environment for all team members, and a culture of continuous improvement for health & safety.
Required Qualifications
  • BSc, MSc, or PhD degree in chemistry with industrial or equivalent experience.
  • Experience in oligonucleotide synthesis and bioconjugation.
  • Practical knowledge of small molecules and oligonucleotide analysis and purification.
  • Strong problem‑solving and analytical skills.
  • Strong attention to detail and a high level of organization.
  • A willingness to learn and develop is essential, as training will be given.
Desired Qualifications
  • Experience in nucleosides, phosphoramidites, and triphosphates synthesis.

Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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Research Scientist - Oligonucleotide Synthesis employer: Oxford Nanopore Technologies

At Oxford Nanopore Technologies, we pride ourselves on being an excellent employer, offering a dynamic work environment that fosters innovation and collaboration. Our commitment to employee growth is evident through comprehensive training programmes and opportunities for technical leadership within our cutting-edge oligonucleotide facility. Located in the heart of the UK, we provide a supportive culture that values safety, continuous improvement, and the pursuit of ambitious R&D projects, making it an ideal place for motivated individuals seeking meaningful and rewarding careers.

Oxford Nanopore Technologies

Contact Details:

Oxford Nanopore Technologies Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Research Scientist - Oligonucleotide Synthesis

Tip Number 1

Network like a pro! Reach out to people in the oligonucleotide synthesis field on LinkedIn or at industry events. A friendly chat can lead to opportunities that aren’t even advertised yet.

Tip Number 2

Show off your skills! If you’ve got experience with oligonucleotide synthesis, consider creating a portfolio of your work. This could include projects, methodologies, or even presentations that highlight your expertise.

Tip Number 3

Prepare for interviews by brushing up on your technical knowledge. Be ready to discuss your experience with nucleosides and purification techniques, as well as how you can contribute to the team’s R&D goals.

Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our innovative team.

We think you need these skills to ace Research Scientist - Oligonucleotide Synthesis

Oligonucleotide Synthesis
Nucleotide Chemistry
Analytical Methodologies
Purification Workflows
High-Resolution CE
LC-MS
HPLC

Some tips for your application 🫡

Tailor Your CV:Make sure your CV is tailored to the role of Research Scientist in Oligonucleotide Synthesis. Highlight your relevant experience in nucleotide chemistry and oligonucleotide synthesis, as well as any specific methodologies you've worked with.

Craft a Compelling Cover Letter:Your cover letter should tell us why you're excited about this position and how your background makes you a great fit. Be sure to mention your problem-solving skills and any innovative projects you've been involved in.

Showcase Your Technical Skills:In your application, don't forget to showcase your technical skills, especially in oligonucleotide analysis and purification. Mention any experience with high-resolution CE, LC-MS, or HPLC, as these are key to the role.

Apply Through Our Website:We encourage you to apply through our website for a smoother application process. This way, we can easily track your application and ensure it gets the attention it deserves!

How to prepare for a job interview at Oxford Nanopore Technologies

Know Your Nucleotides

Make sure you brush up on your knowledge of oligonucleotide synthesis and the specific methodologies mentioned in the job description. Be prepared to discuss your experience with nucleosides, phosphoramidites, and triphosphates, as well as any relevant analytical techniques like CE, LC-MS, and HPLC.

Showcase Your Problem-Solving Skills

During the interview, highlight examples where you've tackled complex problems in a lab setting. Discuss how you approached these challenges, the methodologies you developed, and the outcomes. This will demonstrate your analytical skills and ability to contribute to innovative R&D projects.

Emphasise Team Collaboration

Since this role involves working closely with other team members, be ready to share experiences that showcase your ability to collaborate effectively. Talk about how you've contributed to team goals, supported colleagues, or led initiatives that improved workflows or safety in the lab.

Prepare for Technical Questions

Expect technical questions related to oligonucleotide synthesis and purification processes. Review common challenges in the field and think about how you would approach them. Being able to articulate your thought process will show your depth of knowledge and readiness for the role.