Research Scientist - Oligonucleotide Synthesis in Harwell
Research Scientist - Oligonucleotide Synthesis

Research Scientist - Oligonucleotide Synthesis in Harwell

Harwell Full-Time 35000 - 45000 £ / year (est.) No home office possible
Oxford Nanopore Technologies

At a Glance

  • Tasks: Join our team to develop innovative oligonucleotide synthesis methodologies and support exciting R&D projects.
  • Company: Oxford Nanopore Technologies, a leader in real-time DNA/RNA analysis.
  • Benefits: Competitive salary, hands-on experience, and opportunities for professional growth.
  • Other info: Dynamic, fast-paced environment with a focus on innovation and collaboration.
  • Why this job: Make a real impact in cutting-edge biotechnology and contribute to groundbreaking research.
  • Qualifications: BSc, MSc, or PhD in chemistry; experience in oligonucleotide synthesis preferred.

The predicted salary is between 35000 - 45000 £ per year.

Oligonucleotide Scientist - Oligonucleotide Synthesis Team

Location: Harwell, Oxfordshire

Work Model: Fully on-site

About Oxford Nanopore Technologies

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and a commercial presence in many global locations across the US, APAC, and Europe. Our goal is to enable the analysis of any living thing, by anyone, anywhere. We employ individuals from multiple subject areas, including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing, and commercialisation. Our sequencing platform is the only technology that offers real-time analysis, in fully scalable formats from pocket to population scale. This platform can analyze native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths.

The Role:

We are seeking a highly motivated Oligonucleotide Scientist to join our newly established Oligonucleotide Synthesis Team. This is an exciting and challenging role where you will assist in expanding our nucleotide and oligonucleotide synthesis capabilities aimed at research and development (R&D). Depending on experience, the successful candidate will take on technical leadership roles and collaborate closely with other team members in the oligonucleotide facility. This role involves developing new synthesis, purification, and analytical methodologies/workflows for a wide range of critical long and modified DNA/RNA oligonucleotides. You will also play a collaborative role in the strategic decision-making that influences future projects for the team and the company.

Key Responsibilities

  • Developing an oligonucleotide synthesis pipeline to serve critical R&D projects.
  • Developing synthesis methodologies for complex, modified, and long DNA/RNA oligonucleotides.
  • Improving purification and analytical workflows for synthesized oligonucleotides, introducing automation where possible.
  • Analysing oligonucleotides by high-resolution CE, LC-MS, and HPLC.
  • Onboarding new technology and methods to improve operational effectiveness.
  • Contributing to the scientific and technical training of the team.
  • Supporting ambitious and innovative R&D projects.
  • Preparing clearly articulated progress reports and keeping well-organized experimental records.
  • Working and communicating effectively across several research and development groups.
  • Promoting a safe working environment for all team members, and a culture of continuous improvement for health & safety.

Required Qualifications

  • BSc, MSc, or PhD degree in chemistry with industrial or equivalent experience.
  • Experience in oligonucleotide synthesis and bioconjugation.
  • Practical knowledge of small molecules and oligonucleotide analysis and purification.
  • Strong problem-solving and analytical skills.
  • Strong attention to detail and a high level of organization.
  • A willingness to learn and develop is essential, as training will be given.

Desired Qualifications

  • Experience in nucleosides, phosphoramidites, and triphosphates synthesis.

Applications are encouraged from highly motivated individuals who enjoy taking on new challenges, are quickly adaptable in an exciting and fast-paced environment, and who perform well under pressure.

Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Research Scientist - Oligonucleotide Synthesis in Harwell employer: Oxford Nanopore Technologies

Oxford Nanopore Technologies is an exceptional employer located in the vibrant Oxford Science Park, offering a dynamic work environment that fosters innovation and collaboration. With a strong commitment to employee growth, we provide extensive training opportunities and encourage our team members to take on leadership roles in exciting R&D projects. Our culture prioritises safety, continuous improvement, and the pursuit of groundbreaking advancements in oligonucleotide synthesis, making it a rewarding place for passionate scientists to thrive.
Oxford Nanopore Technologies

Contact Detail:

Oxford Nanopore Technologies Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Research Scientist - Oligonucleotide Synthesis in Harwell

✨Tip Number 1

Network like a pro! Reach out to current employees at Oxford Nanopore Technologies on LinkedIn or through mutual connections. A friendly chat can give you insider info and might just get your foot in the door.

✨Tip Number 2

Prepare for the interview by diving deep into their oligonucleotide synthesis projects. Show us that you’re not just familiar with the basics, but that you’re genuinely excited about contributing to their innovative R&D efforts.

✨Tip Number 3

Practice your problem-solving skills! Be ready to tackle some technical questions or case studies during the interview. We want to see how you think on your feet and approach challenges in real-time.

✨Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows us you’re serious about joining the team!

We think you need these skills to ace Research Scientist - Oligonucleotide Synthesis in Harwell

Oligonucleotide Synthesis
Bioconjugation
Analytical Methodologies
Purification Workflows
High-Resolution Capillary Electrophoresis (CE)
Liquid Chromatography-Mass Spectrometry (LC-MS)
High-Performance Liquid Chromatography (HPLC)
Problem-Solving Skills
Attention to Detail
Organisational Skills
Adaptability
Technical Leadership
Collaboration
Scientific Training

Some tips for your application 🫡

Tailor Your CV: Make sure your CV is tailored to the role of Oligonucleotide Scientist. Highlight your experience in oligonucleotide synthesis and any relevant projects you've worked on. We want to see how your skills align with our needs!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about this role and how you can contribute to our team. Be sure to mention any specific methodologies or technologies you're familiar with that relate to the position.

Showcase Your Problem-Solving Skills: In your application, don’t forget to highlight your problem-solving abilities. Share examples of challenges you've faced in previous roles and how you overcame them. We love candidates who can think on their feet and adapt quickly!

Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it shows you’re keen to join our team at Oxford Nanopore Technologies!

How to prepare for a job interview at Oxford Nanopore Technologies

✨Know Your Science

Brush up on your knowledge of oligonucleotide synthesis and related methodologies. Be prepared to discuss your experience with complex, modified, and long DNA/RNA oligonucleotides, as well as any relevant analytical techniques like CE, LC-MS, and HPLC.

✨Show Your Problem-Solving Skills

Prepare examples of how you've tackled challenges in previous roles. Highlight your strong analytical skills and attention to detail, as these are crucial for the role. Think of specific instances where you improved workflows or introduced new technologies.

✨Demonstrate Team Collaboration

Since this role involves working closely with other team members, be ready to share experiences that showcase your ability to communicate effectively and collaborate across different research groups. Emphasise your willingness to contribute to a positive team culture.

✨Ask Insightful Questions

Prepare thoughtful questions about the company's R&D projects and future directions. This shows your genuine interest in the role and helps you understand how you can contribute to their goals. It’s also a great way to demonstrate your enthusiasm for continuous improvement.

Research Scientist - Oligonucleotide Synthesis in Harwell
Oxford Nanopore Technologies
Location: Harwell

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