At a Glance
- Tasks: Support drug substance characterisation and lead innovative research projects.
- Company: Join Immunocore, a pioneering biotech company transforming medicine.
- Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
- Other info: Collaborative environment with a focus on diversity and innovation.
- Why this job: Make a real impact in developing breakthrough therapies for patients in need.
- Qualifications: BSc or MSc in biochemistry; experience in protein characterisation preferred.
The predicted salary is between 50000 - 65000 € per year.
Responsibilities
- Supporting drug substance and drug product impurity characterisation and identification.
- Performing protein sequence and post translational modification identification, including glycosylation analysis.
- Supporting drug substance and drug product process development by performing characterisation of process intermediates.
- Contributing to the development of characterisation methods of ImmTAX and other products, including peptide mapping (LC-MS/MS) and intact mass analysis.
- Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products.
- Contributing to writing study protocols and reports.
- Independently testing and, increasingly, leading lines of investigation.
- Proposing new experiments based on emerging data and other related information.
- Providing support on technical aspects to others.
Priorities
- Establishing priorities for own work and team-based projects.
- Making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.
Technical Knowledge
- Sharing knowledge with the wider team and across departments representing the department.
- May also act as a mentor to other colleagues, sharing scientific knowledge.
- Providing analysis of new techniques and theories from outside the company to advance the way the company works; sharing these with leaders across the department.
Laboratory records
- Ensuring that all records and information are up to date, on time and recorded to the correct standard.
- Supporting and encouraging others to achieve this.
Laboratory equipment
- Providing technical guidance to others within the team on how to use equipment most effectively.
Reporting
- Communicating and presenting research findings at meetings with colleagues, senior management and partners.
- Adhering to safe working practices in laboratories according to Immunocore EHS policies.
Experience & Knowledge
Essential
- Experience in development of HPLC based peptide mapping methods and mass spectrometric characterisation of recombinant proteins or antibodies.
- Experience of glycosylation analysis of recombinant proteins or antibodies.
- Independently coordinated extensive testing of protein biomolecules.
- Experienced in the characterisation of proteins expressed in both microbial and mammalian systems.
- Understanding of expected post‑translational modifications in biological systems.
- Worked in a bench‑based biopharmaceutical laboratory environment.
- Established as an expert amongst peers in one or more of the following areas: electrophoretic, chromatographic, mass spectrometry.
- Experienced in assay development.
- Familiar with biopharmaceutical stability study principles and interpretation thereof.
- Worked and contributed actively in a diverse team environment.
- Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change.
- Presented detailed scientific findings and papers to internal and external audiences.
Desirable
- Experience of glycosylation analysis of recombinant proteins or antibodies.
- Experience with late stage/commercial biopharmaceutical assay development and characterisation.
- Familiar with the principles of Good Manufacturing Practice (GMP).
- Presented at external conferences.
- Led a small project team, formally or informally, through a change in practice including project management.
- Understanding of analytical requirements to support materials for use in clinical trials.
Education & Qualifications
Essential: BSc or MSc in biochemistry, biotechnology or related discipline.
Desirable: PhD in related discipline.
Senior Scientist I - Characterisation | CMC - Oxford in Princes Risborough employer: Oxford Immunocore (nasdaq: Imcr)
Immunocore is an exceptional employer located in Oxford, offering a dynamic work culture that fosters innovation and collaboration. With a strong commitment to employee growth, we provide opportunities for professional development and mentorship, ensuring that our team members thrive in their careers while contributing to groundbreaking therapies that transform patients' lives. Our inclusive environment, guided by our STRIDE values, empowers every individual to make meaningful contributions to the field of biotechnology.
Contact Detail:
Oxford Immunocore (nasdaq: Imcr) Recruiting Team
StudySmarter Expert Advice🤫
We think this is how you could land Senior Scientist I - Characterisation | CMC - Oxford in Princes Risborough
✨Tip Number 1
Network like a pro! Reach out to your connections in the biopharmaceutical field, especially those who work at Immunocore or similar companies. A friendly chat can lead to insider info about job openings and even referrals.
✨Tip Number 2
Prepare for interviews by brushing up on your technical knowledge. Be ready to discuss your experience with HPLC, mass spectrometry, and glycosylation analysis. Show us how you can contribute to our innovative projects!
✨Tip Number 3
Don’t just wait for job postings! Keep an eye on our website and apply directly. We love proactive candidates who take the initiative to reach out and express their interest in joining our team.
✨Tip Number 4
Showcase your teamwork skills! At Immunocore, collaboration is key. Share examples of how you've worked effectively in diverse teams and contributed to successful projects in your previous roles.
We think you need these skills to ace Senior Scientist I - Characterisation | CMC - Oxford in Princes Risborough
Some tips for your application 🫡
Tailor Your CV:Make sure your CV highlights your experience in HPLC, mass spectrometry, and glycosylation analysis. We want to see how your skills align with the responsibilities listed in the job description.
Showcase Your Team Spirit:Since we value collaboration, share examples of how you've worked in diverse teams. Highlight any leadership roles or mentoring experiences you've had, as this shows us you're a team player.
Be Clear and Concise:When writing your cover letter, get straight to the point. Clearly explain why you're a great fit for the Senior Scientist role and how your background supports our mission at Immunocore.
Apply Through Our Website:We encourage you to apply directly through our website. This ensures your application gets to the right people and helps us keep track of all candidates efficiently.
How to prepare for a job interview at Oxford Immunocore (nasdaq: Imcr)
✨Know Your Science
Make sure you brush up on your knowledge of HPLC, mass spectrometry, and glycosylation analysis. Be ready to discuss your experience with these techniques in detail, as they are crucial for the role. Prepare examples of how you've applied these methods in past projects.
✨Showcase Your Problem-Solving Skills
Be prepared to talk about specific challenges you've faced in your previous roles and how you overcame them. Highlight any instances where you proposed new experiments or improved processes based on emerging data. This will demonstrate your ability to think critically and contribute to the team.
✨Communicate Effectively
Since you'll be presenting findings to colleagues and management, practice explaining complex scientific concepts in a clear and concise manner. Consider preparing a brief presentation or summary of a past project to showcase your communication skills during the interview.
✨Emphasise Team Collaboration
Immunocore values teamwork, so be ready to discuss your experiences working in diverse teams. Share examples of how you've supported colleagues or led small project teams, and highlight your ability to mentor others. This will show that you can thrive in their collaborative environment.
