Scientist IV Process Development (Downstream) in Oxford

Location: Oxford, GB

Join Us in Changing Lives

At OXB, our people are at the heart of everything we do. We’re on a mission to enable life-changing therapies to reach patients around the world—and we’re looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.

We’re currently recruiting for a Scientist IV - Process Development (Downstream) to join our Downstream Process Development team. In this role, you will perform and report laboratory-based experiments or investigations in accordance with scientific or regulatory requirements in line with departmental objectives, playing a key part in advancing our mission and making a real difference.

Your responsibilities in this role would be:

• Involvement in a range of activities including vector production at laboratory and pilot scales, process development and optimisation, technology transfer, and process characterization activities associated with the manufacture of new gene therapy vectors.
• Design and execute downstream vector purification and vector formulation activities for scale-up/scale-down of existing bioprocesses under the direction of the Team Leader or a senior scientist and in accordance with correct methodologies and procedures.
• Prepare written reports to a high standard and present data within the PD group.
• Liaise with other members of the PD group and assist with other development activities where appropriate.
• Ensure a high standard of record keeping and documentation of experiments and investigations.
• Writing of departmental risk assessments, SOPs, and other documentation where appropriate.

We are looking for:

• Minimum BSc Degree programme level and/or relevant experience.
• Sound understanding of downstream purification principles and processes.
• Competency in data capture, reporting and management systems.
• Familiarity with data analysis software packages such as Microsoft Excel, JMP, Design Expert™, GraphPad Prism.
• Experience with the operation of laboratory, pilot or production scale downstream purification processes.
• Pharmaceutical industry experience in biological research and development or equivalent experience gained elsewhere desirable, but not necessary.
• The ability to explain clearly why an experiment is being conducted and how the experiments help the group meet their objectives.
• Awareness of regulatory requirements e.g. GMP, GLP, GCP and/or Validation and Quality Management systems.
• Fluency in written and spoken English.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality‑assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us?

• Wellbeing programmes that support your mental and physical health
• Career development opportunities to help you grow and thrive
• Supportive, inclusive, and collaborative culture
• State-of-the‑art labs and manufacturing facilities
• A company that lives its values: Responsible, Responsive, Resilient, Respect

We want you to feel inspired every day. At OXB, we’re future‑focused and growing fast. We succeed together—through passion, commitment, and teamwork.