Scientist IV Process Development (Downstream) in Oxford

OXB is a quality and innovation-led viral vector CDMO with a mission to enable life-changing therapies to reach patients around the world. We are recruiting for a Scientist IV - Process Development (Downstream) to join our Downstream Process Development team. In this role, you will perform and report laboratory-based experiments or investigations in accordance with scientific or regulatory requirements in line with departmental objectives, playing a key part in advancing our mission and making a real difference.

OXB is a company with over 30 years of experience in viral vectors. We collaborate with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Our capabilities span from early-stage development to commercialisation, supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

• Involvement in activities including vector production at laboratory and pilot scales, process development and optimisation, technology transfer, and process characterization for the manufacture of new gene therapy vectors.
• Design and execute downstream vector purification and vector formulation activities for scale-up/scale-down of existing bioprocesses under the direction of the Team Leader or a senior scientist and in accordance with correct methodologies and procedures.
• Prepare written reports to a high standard and present data within the PD group.
• Liaise with other members of the PD group and assist with other development activities where appropriate.
• Ensure a high standard of record keeping and documentation of experiments and investigations.
• Writing of departmental risk assessments, SOPs, and other documentation where appropriate.

• Minimum BSc Degree programme level and/or relevant experience.
• Sound understanding of downstream purification principles and processes.
• Competency in data capture, reporting and management systems.
• Familiarity with data analysis software packages such as Microsoft Excel, JMP, Design Expert, GraphPad Prism.
• Experience with the operation of laboratory, pilot or production scale downstream purification processes.
• Pharmaceutical industry experience in biological research and development or equivalent experience gained elsewhere desirable, but not necessary.
• The ability to explain clearly why an experiment is being conducted and how the experiments help the group meet their objectives.
• Awareness of regulatory requirements e.g. GMP, GLP, GCP and/or Validation and Quality Management systems.
• Fluency in written and spoken English.

• Competitive total reward packages.
• Wellbeing programmes that support your mental and physical health.
• Career development opportunities to help you grow and thrive.
• Supportive, inclusive, and collaborative culture.
• State-of-the-art labs and manufacturing facilities.
• A company that lives its values: Responsible, Responsive, Resilient, Respect.

We want you to feel inspired every day. At OXB, we’re future-focused and growing fast. We succeed together-through passion, commitment, and teamwork. Ready to Make a Difference? Collaborate. Contribute. Change lives.