Find a job 
Featured Companies 
Featured Universities 
For Companies At a Glance
- Tasks: Join us in developing innovative processes for viral vector production in a dynamic lab environment.
- Company: Orchard Therapeutics is a global leader in gene therapy, transforming lives through cutting-edge treatments.
- Benefits: Enjoy a collaborative workspace in London with opportunities for professional growth and impactful work.
- Why this job: Be part of a mission-driven team making a difference in patients' lives through advanced gene therapies.
- Qualifications: MSc in a relevant field with at least one year of experience in biotechnology or pharmaceuticals required.
- Other info: This is a 10-month fixed-term contract role based in Hammersmith, London.
The predicted salary is between 36000 - 60000 £ per year.
Contract: 10-month fixed-term contract Location: London (Hammersmith) Reporting to: Director, Viral Vector Development Orchard Therapeutics, a Kyowa Kirin company, is a global gene therapy leader focused on transforming the life of patients with rare disorders through innovative gene therapies based on gene-modified hematopoietic stem cells (HSC). Orchard has its global headquarters in London and U.S. headquarters in Boston. Technical Development sits within Technical Operations at Orchard and is responsible for the development and characterization of Lentiviral Vectors (LVVs) and DS/DP production processes, which meet patient demand for therapeutic products of the best quality. Reporting to the Director, Viral Vector Development, the Scientist II, Viral Vector Development, will support the Principal Scientist in the development of innovative, high-yield processes for production of lentiviral vectors to support early, and late-stage clinical studies. This role is based in our Hammersmith, London facilities within our global headquarters and will suit candidates who would like to join a global cell and gene therapy company with a diverse and dynamic work environment. Key Elements and Responsibilities · Support the design, development and improvement of upstream and downstream processes for LVVs to deliver robust manufacturing platforms for early and late-stage clinical and commercial development · Compile process data, prepare databases to analyse results, confirm scientific hypotheses and/or propose new experiments · Prepare, review and complete study reports and protocols/SOPs · Assist with CMC and regulatory submissions · Contribute to routine lab maintenance · Communicate, share and discuss work progress internally and where appropriate with external partners · Regularly exchange with external partners and CDMOs on process development and manufacturing activities to support ongoing projects. Experience & Knowledge · Experience in biotechnology or pharmaceutical industry with a primary focus on the process development and manufacturing of viral vectors, preferably retro and lentiviral vectors · Experience in cell line culture techniques and handling of adherent and suspension cell lines in different culture systems, with demonstrated skills in aseptic techniques · Knowledge in bioprocessing, purification of viral vectors and virology · Use of more specialist lab equipment e.g. bioreactors, AKTA or TFF systems is ideal · Proficiency with MS office, MFCS, SnapGene, Unicorn, electronic lab-books and/or other commonly used software Skills & Abilities · Ability to operate in a fast paced, multidisciplinary environment · Ability to document and maintain record of lab work, raw data and results · Strong organization and planning skills · Good communication and written skills for report-writing, team communications and presentations · Able to independently design and execute experiments following laboratory procedures, appropriately analyse data and provide an interpretation of results · Creativeness, motivation, and troubleshooting skills to solve problems and/or develop new technical capabilities Education · A minimum MSc or equivalent in a relevant scientific discipline: bioprocessing, cell and gene therapy, biological sciences, biotechnology etc, combined with at least one year of industrial experience. #J-18808-Ljbffr
Scientist II, Viral Vector Development employer: Orchard Therapeutics
Contact Detail:
Orchard Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist II, Viral Vector Development
✨Tip Number 1
Familiarize yourself with the latest advancements in lentiviral vector development. This will not only help you understand the current landscape but also allow you to engage in meaningful conversations during interviews.
✨Tip Number 2
Network with professionals in the biotechnology and pharmaceutical industries, especially those involved in viral vector production. Attend relevant conferences or webinars to make connections that could lead to opportunities at Orchard Therapeutics.
✨Tip Number 3
Prepare to discuss your hands-on experience with bioprocessing and purification techniques. Be ready to share specific examples of how you've successfully managed lab work and contributed to process improvements in previous roles.
✨Tip Number 4
Showcase your ability to work in a multidisciplinary environment by highlighting any collaborative projects you've been part of. Emphasize your communication skills and how you've effectively shared progress with team members and external partners.
We think you need these skills to ace Scientist II, Viral Vector Development
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in biotechnology or the pharmaceutical industry, especially focusing on process development and manufacturing of viral vectors. Include specific examples of your work with lentiviral vectors and any relevant technical skills.
Craft a Strong Cover Letter: In your cover letter, express your passion for gene therapy and how your background aligns with the role. Mention your experience with cell line culture techniques and any familiarity with bioprocessing and purification of viral vectors.
Highlight Technical Skills: Clearly outline your proficiency with lab equipment such as bioreactors and AKTA systems. Mention any software tools you are familiar with, like MS Office, SnapGene, or electronic lab books, as these are crucial for the role.
Showcase Communication Skills: Since good communication is essential for this position, provide examples of how you've effectively documented lab work, prepared reports, or collaborated with team members and external partners in previous roles.
How to prepare for a job interview at Orchard Therapeutics
✨Showcase Your Technical Expertise
Be prepared to discuss your experience with viral vector development, particularly lentiviral vectors. Highlight specific projects where you contributed to process development and manufacturing, and be ready to explain the techniques and equipment you used.
✨Demonstrate Problem-Solving Skills
Think of examples where you faced challenges in the lab and how you overcame them. This role requires creativity and troubleshooting skills, so sharing relevant experiences will show that you can thrive in a fast-paced environment.
✨Communicate Effectively
Since the position involves collaboration with internal teams and external partners, practice articulating your thoughts clearly. Prepare to discuss how you have communicated complex scientific concepts in previous roles, especially in report writing and presentations.
✨Prepare for Regulatory Discussions
Familiarize yourself with CMC and regulatory submission processes. Be ready to discuss any experience you have in this area, as it is crucial for supporting clinical studies and ensuring compliance in the development of therapeutic products.
