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For Companies At a Glance
- Tasks: Join us in designing and conducting groundbreaking research on cell and gene therapies for brain diseases.
- Company: Orchard Therapeutics, now part of Kyowa Kirin, is a leader in innovative cell and gene therapy solutions.
- Benefits: Enjoy working in vibrant London with opportunities for professional growth and collaboration.
- Why this job: Be part of a pioneering team making a real impact in the field of neuroscience and therapeutic development.
- Qualifications: PhD in a relevant biological discipline and 5 years of lab experience in cell biology required.
- Other info: This is a fixed-term contract role based in our Hammersmith Research facility.
The predicted salary is between 48000 - 72000 £ per year.
Location: London, UK
Reporting to: Director, Translational Research
Job Summary
Orchard Therapeutics, recently acquired by Kyowa Kirin, is a pioneering company in the field of cell and gene therapy where the Translational Research Department develops novel and innovative applications of Orchard’s platform of hematopoietic stem cell gene therapy. This role will be based in the heart of London in our Hammersmith Research facility. The Scientist will perform experimental laboratory duties related to the design and development of experimental research models to evaluate the feasibility and the efficacy of cell and gene therapies in brain disease models and/or other research programs under development by the Translational Research Team. The role will specifically involve performing pre-clinical research using in vitro cell culture and analytical techniques, and the use of in vivo models required to evaluate the Translational Research Team’s expanding projects in developing new therapeutic targets and approaches to treat brain diseases. The Scientist will work closely with the Directors & Senior Scientists to design and plan experiments, establish and run experimental studies, ensure compliance in documentation and reporting, and provide key support for lab functions.
Key Elements and Responsibilities
- Contribute towards the design, planning and conduct of experimental pre-clinical research models and studies for assigned research programs.
- Perform in vitro and in vivo experiments in the laboratory, including data analysis, interpretation and presentation.
- Oversee the preparation, review and completion of study reports and protocol SOPs.
- Work with other scientists to develop new ideas and solutions to research problems.
- Contribute to the overall activities of the research team and department as required, including laboratory duties, attendance and participation in group and department meetings.
Required Knowledge and Skills
- Extensive experience of working within the field of brain cancer and/or neurodegeneration:
- extensive expertise in in vivo models of brain diseases
- extensive experience in in vitro cell culture, using cell lines, primary cells and cell isolation methods
- knowledge of immunology / immuno-oncology
- experience of conducting intra-cerebral cell injection and immunohistochemistry techniques
Qualifications/ Experience
- Candidate must possess:
- PhD (or equivalent) with focus on a relevant biological discipline is essential.
- At least 5 years of experience of laboratory work in cell biology, molecular biology and in vivo mouse models is essential.
- An active Home Office PIL.
Scientist II, Translational Research (Fixed Term Contract - 12 months) employer: Orchard Therapeutics
Contact Detail:
Orchard Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist II, Translational Research (Fixed Term Contract - 12 months)
✨Tip Number 1
Network with professionals in the field of translational research, especially those who have experience in brain cancer and neurodegeneration. Attend relevant conferences or seminars where you can meet potential colleagues and learn more about the latest advancements in cell and gene therapy.
✨Tip Number 2
Familiarise yourself with the specific techniques mentioned in the job description, such as in vivo models and immunohistochemistry. Consider reaching out to current or former employees at Orchard Therapeutics to gain insights into their research methodologies and laboratory culture.
✨Tip Number 3
Prepare to discuss your previous research experiences in detail during interviews. Be ready to explain how your skills in data analysis and experimental design can contribute to the ongoing projects at Orchard Therapeutics, particularly in developing new therapeutic targets.
✨Tip Number 4
Showcase your ability to work both independently and as part of a team. Highlight any collaborative projects you've been involved in, as well as your experience in presenting research findings clearly, which is crucial for this role.
We think you need these skills to ace Scientist II, Translational Research (Fixed Term Contract - 12 months)
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in cell biology, molecular biology, and in vivo mouse models. Emphasise any specific projects or roles that align with the responsibilities outlined in the job description.
Craft a Strong Cover Letter: Write a cover letter that clearly articulates your passion for translational research and how your background fits the role. Mention your experience with in vitro and in vivo techniques, as well as your ability to work independently and collaboratively.
Highlight Relevant Skills: In your application, be sure to showcase your expertise in immunology, advanced analytical methods, and any specific techniques mentioned in the job description, such as flow cytometry and ELISA.
Proofread Your Application: Before submitting, carefully proofread your application materials for any errors or inconsistencies. A polished application reflects your attention to detail, which is crucial for this role.
How to prepare for a job interview at Orchard Therapeutics
✨Showcase Your Expertise
Make sure to highlight your extensive experience in brain cancer and neurodegeneration during the interview. Be prepared to discuss specific projects or research you've conducted, particularly those involving in vivo models and cell culture techniques.
✨Demonstrate Analytical Skills
Since the role requires keen attention to detail and strong analytical abilities, be ready to provide examples of how you've interpreted data and completed study reports in your previous roles. This will show that you can handle the responsibilities of the position effectively.
✨Prepare for Technical Questions
Expect technical questions related to immunology, advanced assays, and analytical methods like flow cytometry and ELISA. Brush up on these topics and be ready to explain your hands-on experience with them, as this will demonstrate your suitability for the role.
✨Emphasise Team Collaboration
The job involves working closely with other scientists, so it's important to convey your ability to collaborate effectively. Share examples of how you've contributed to team projects and how you approach problem-solving in a group setting.
