At a Glance
- Tasks: Lead drug discovery using 3D molecular modelling and support customers with innovative software solutions.
- Company: Optibrium, a pioneering software company in drug discovery based in Cambridge, UK.
- Benefits: Flexible working, competitive salary, private medical cover, and gym discounts.
- Other info: Collaborative environment with opportunities for professional growth and representation at industry events.
- Why this job: Join a team making a real impact in drug discovery with cutting-edge technology.
- Qualifications: PhD in relevant field and experience in molecular modelling and drug design.
The predicted salary is between 60000 - 80000 £ per year.
Founded in 2009 and headquartered in Cambridge, UK, Optibrium develops software and novel technologies to improve the efficiency and productivity of drug discovery. Our solutions support industry-leading research for a global customer base, including top ten pharma and innovative biotech companies.
Optibrium software solutions include:
- StarDrop ™ – A complete package of fully integrated software for multi-objective small molecule design, optimisation, and data analysis;
- Cerella ™ – A unique platform for the imputation of drug discovery data, revealing insights into the best compounds and most valuable experiments;
- BioPharmics ™ – A fast, robust, and accurate 3D ligand- and structure-based design platform that scales from small molecules to large macrocycles.
With a strong track record of translating peer‑reviewed science into successful products and a growing blue‑chip customer base for BioPharmics, we are recruiting a Senior or Principal Scientist – 3D Molecular Modelling to help customers achieve challenging drug discovery objectives and maximise the value of our software.
About the Role
As a Senior or Principal Scientist you will:
- Apply 3D structure‑based and ligand‑based design approaches to lead discovery and optimisation.
- Support current and prospective customers in the effective use of BioPharmics, working with the commercial team to communicate its value clearly and scientifically.
- Use NMR and X‑ray crystallography data in combination with the BioPharmics modelling methods.
- Provide guidance on the development of the BioPharmics platform by identifying unmet customer needs and translating them into product and research opportunities.
- Represent Optibrium’s science and products at conferences, workshops, and customer meetings.
About You
The ideal candidate will have the following experience:
- PhD in computational chemistry, computer science, chemistry, biophysics, or a related discipline.
- Strong understanding of structure‑based and ligand‑based drug design, ideally including experience with macrocycles and peptides.
- Experience with molecular modelling and visualisation platforms, e.g., PyMOL and MOE.
- Experience with structural data (NMR and X‑ray crystallography) applied to molecular design problems.
- A track record of high‑quality peer‑reviewed publications and conference presentations.
- The ability to work effectively with customers, collaborators, and cross‑functional teams.
What We Offer
We offer hybrid & flexible working, a competitive base salary, pension contribution, employee private medical and dental cover, life assurance, corporate gym discount and cycle to work scheme.
Senior or Principal Scientist – 3D Molecular Modelling in Cambridge employer: Optibrium
Optibrium is an exceptional employer, offering a dynamic work environment in the heart of Cambridge, where innovation meets collaboration. With a strong commitment to employee growth, we provide opportunities for professional development alongside competitive benefits such as hybrid working, private medical cover, and a corporate gym discount. Join us to be part of a pioneering team that translates cutting-edge science into impactful solutions for drug discovery.
StudySmarter Expert Advice🤫
We think this is how you could land Senior or Principal Scientist – 3D Molecular Modelling in Cambridge
✨Tip Number 1
Network like a pro! Reach out to professionals in the field of molecular modelling on LinkedIn or at conferences. We can’t stress enough how valuable personal connections can be in landing that dream job.
✨Tip Number 2
Showcase your expertise! Create a portfolio or a personal website where you can display your projects, publications, and any relevant work. This gives potential employers a taste of what you can bring to the table.
✨Tip Number 3
Prepare for interviews by brushing up on your technical knowledge and soft skills. We recommend practising common interview questions related to 3D molecular modelling and being ready to discuss your past experiences in detail.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team at Optibrium.
We think you need these skills to ace Senior or Principal Scientist – 3D Molecular Modelling in Cambridge
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to the Senior or Principal Scientist role. Highlight your experience in 3D molecular modelling and any relevant software you've used, like BioPharmics. We want to see how your skills match what we're looking for!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about drug discovery and how your background fits with our mission at Optibrium. Be sure to mention specific projects or experiences that relate to the role.
Showcase Your Publications:If you have peer-reviewed publications, make sure to include them in your application. This shows us your expertise and commitment to the field. We love seeing candidates who have made significant contributions to scientific literature!
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it gives you a chance to explore more about us and what we do at Optibrium!
How to prepare for a job interview at Optibrium
✨Know Your Stuff
Make sure you brush up on your knowledge of 3D molecular modelling and the specific software tools mentioned in the job description, like BioPharmics. Be ready to discuss how you've applied structure-based and ligand-based design approaches in your previous work.
✨Showcase Your Experience
Prepare to talk about your PhD research and any relevant publications or presentations. Highlight your experience with NMR and X-ray crystallography data, and how it relates to molecular design problems. This will demonstrate your expertise and fit for the role.
✨Engage with the Team
Since collaboration is key, think about examples where you've worked effectively with customers or cross-functional teams. Be ready to discuss how you can support the commercial team in communicating the value of BioPharmics to clients.
✨Ask Insightful Questions
Prepare some thoughtful questions about Optibrium's current projects or future developments in the BioPharmics platform. This shows your genuine interest in the company and helps you understand how you can contribute to their goals.
