At a Glance
- Tasks: Lead drug discovery using 3D modelling and support customers with innovative software solutions.
- Company: Optibrium, a pioneering software company in drug discovery based in Cambridge.
- Benefits: Hybrid working, competitive salary, private medical cover, and gym discounts.
- Other info: Collaborative environment with opportunities for professional growth and representation at conferences.
- Why this job: Join a team making a real impact in drug discovery with cutting-edge technology.
- Qualifications: PhD in relevant field and experience in molecular modelling and drug design.
The predicted salary is between 60000 - 80000 £ per year.
Founded in 2009 and headquartered in Cambridge, UK, Optibrium develops software and novel technologies to improve the efficiency and productivity of drug discovery. Our solutions support industry-leading research for a global customer base, including top ten pharma and innovative biotech companies.
Optibrium software solutions include:
- StarDrop ™ – A complete package of fully integrated software for multi-objective small molecule design, optimisation, and data analysis;
- Cerella ™ – A unique platform for the imputation of drug discovery data, revealing insights into the best compounds and most valuable experiments;
- BioPharmics ™ – A fast, robust, and accurate 3D ligand- and structure-based design platform that scales from small molecules to large macrocycles.
With a strong track record of translating peer‑reviewed science into successful products and a growing blue‑chip customer base for BioPharmics, we are recruiting a Senior or Principal Scientist – 3D Molecular Modelling to help customers achieve challenging drug discovery objectives and maximise the value of our software.
About the Role
As a Senior or Principal Scientist you will:
- Apply 3D structure‑based and ligand‑based design approaches to lead discovery and optimisation;
- Support current and prospective customers in the effective use of BioPharmics, working with the commercial team to communicate its value clearly and scientifically;
- Use NMR and X‑ray crystallography data in combination with the BioPharmics modelling methods;
- Provide guidance on the development of the BioPharmics platform by identifying unmet customer needs and translating them into product and research opportunities;
- Represent Optibrium’s science and products at conferences, workshops, and customer meetings.
About You
The ideal candidate will have the following experience:
- PhD in computational chemistry, computer science, chemistry, biophysics, or a related discipline;
- Strong understanding of structure‑based and ligand‑based drug design, ideally including experience with macrocycles and peptides;
- Experience with molecular modelling and visualisation platforms, e.g., PyMOL and MOE;
- Experience with structural data (NMR and X‑ray crystallography) applied to molecular design problems;
- A track record of high‑quality peer‑reviewed publications and conference presentations;
- The ability to work effectively with customers, collaborators, and cross‑functional teams.
What We Offer
We offer hybrid & flexible working, a competitive base salary, pension contribution, employee private medical and dental cover, life assurance, corporate gym discount and cycle to work scheme.
Senior 3D Modelling Scientist - Hybrid & Flexible in Cambridge employer: Optibrium
Optibrium is an exceptional employer, offering a dynamic work environment in the heart of Cambridge, UK, where innovation thrives. With a strong commitment to employee growth, we provide opportunities for professional development alongside a competitive salary and comprehensive benefits, including hybrid working options and health coverage. Join us to be part of a collaborative culture that values scientific excellence and supports your career in drug discovery.
StudySmarter Expert Advice🤫
We think this is how you could land Senior 3D Modelling Scientist - Hybrid & Flexible in Cambridge
✨Tip Number 1
Network like a pro! Reach out to people in the industry, attend conferences, and join relevant online forums. We can’t stress enough how valuable personal connections can be in landing that dream job.
✨Tip Number 2
Showcase your skills! Create a portfolio or a GitHub repository with your projects related to 3D modelling and drug design. This gives potential employers a tangible look at what you can do, and we all know actions speak louder than words.
✨Tip Number 3
Prepare for interviews by practising common questions and scenarios specific to 3D molecular modelling. We recommend doing mock interviews with friends or mentors to boost your confidence and refine your answers.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team at Optibrium.
We think you need these skills to ace Senior 3D Modelling Scientist - Hybrid & Flexible in Cambridge
Some tips for your application 🫡
Tailor Your CV:Make sure your CV reflects the skills and experiences that match the Senior 3D Modelling Scientist role. Highlight your expertise in molecular modelling and any relevant software you've used, like PyMOL or MOE.
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about drug discovery and how your background aligns with our mission at Optibrium. Be sure to mention specific projects or achievements that showcase your skills.
Showcase Your Publications:If you have peer-reviewed publications, don’t forget to mention them! This demonstrates your expertise and commitment to the field. Include links or references to your work that are relevant to the role.
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it shows you’re keen on joining our team!
How to prepare for a job interview at Optibrium
✨Know Your Stuff
Make sure you brush up on your 3D molecular modelling knowledge. Familiarise yourself with structure-based and ligand-based design approaches, especially if you've worked with macrocycles and peptides. Being able to discuss your experience with tools like PyMOL and MOE will show you're the right fit for the role.
✨Showcase Your Research
Prepare to talk about your high-quality peer-reviewed publications and any conference presentations you've done. This is your chance to highlight your contributions to the field and how they relate to the work at Optibrium. Bring copies of your papers or a portfolio to share if possible!
✨Understand Their Products
Dive deep into Optibrium's software solutions like BioPharmics and StarDrop. Be ready to discuss how you can help customers maximise their use of these tools. Showing that you understand their value and can communicate it effectively will set you apart from other candidates.
✨Engage with the Team
Demonstrate your ability to work with cross-functional teams by sharing examples of past collaborations. Highlight how you've supported customers or colleagues in achieving their goals. This will show that you’re not just a brilliant scientist but also a great team player!
