At a Glance
- Tasks: Lead the design and delivery of innovative healthcare technology solutions.
- Company: Join Onsera Health, a pioneering health AI company transforming cardiometabolic care.
- Benefits: Competitive salary, equity participation, and a chance to shape engineering culture.
- Other info: Collaborate with top experts and enjoy growth opportunities in a dynamic startup environment.
- Why this job: Make a real impact in healthcare while mentoring the next generation of engineers.
- Qualifications: 8+ years in full-stack development with strong leadership skills.
The predicted salary is between 36000 - 60000 £ per year.
The Challenge
Healthcare technology requires seamless integration of patient-facing applications, clinical systems, external partners, and financial workflows—while maintaining the security, reliability, and auditability that regulated environments demand. As healthcare AI advances and new treatment models emerge, the industry needs engineering leaders who can architect scalable platforms, drive technical excellence, and deliver production-grade systems that translate clinical requirements into real-world outcomes.
The Opportunity
Own the technical delivery and architecture of Onsera's core product platforms, from wearables integration and health data pipelines to member payments and AI workflows. As a player-coach, you'll design and implement full-stack solutions while setting engineering standards and help build and mentor our engineering team as we scale. This role offers the opportunity to shape API-first architectures, lead complex integrations with healthcare partners and SaaS platforms, and transition into engineering leadership as the organization scales.
What You'll Do
- Own technical delivery of multiple Onsera products from design through production and iteration
- Design and implement full-stack solutions spanning frontend applications, backend services, APIs, agentic systems and third-party integrations
- Define and evolve API-first, integration-driven architectures that support internal systems and external partners
- Lead complex integrations with SaaS vendors, healthcare partners, wearables platforms, and pharmacy fulfillment systems
- Architect and implement member payment platforms, including fee collection, reconciliation, and financial reporting
- Define and enforce software engineering standards, including coding conventions, testing practices, and documentation
- Conduct rigorous code reviews focused on correctness, security, performance, and maintainability
- Mentor engineers and gradually transition into line management as the engineering organization grows
Minimum Qualifications
- 8+ years of experience as a Full-Stack Engineer delivering production systems, with track record at Senior or Principal level
- Proficiency across frontend and backend development, including modern web frameworks and API design
- Proven experience integrating with third-party SaaS platforms and external partners
- Strong background in automated testing strategies and quality-driven development
- Experience acting as a technical leader or player-coach with demonstrated ability to mentor engineers
- Comfortable collaborating with product, data, clinical, and non-technical stakeholders
Preferred Qualifications
- Strong written and verbal communication skills for technical and cross-functional collaboration
- Experience working with Python
- Experience with payments, billing, or financial reconciliation systems
- Experience in healthtech, regulated environments, or sensitive data systems
- Familiarity with health data ingestion, wearable platforms (Apple HealthKit, Google Fit, Fitbit), or healthcare interoperability patterns
- Exposure to FHIR-based data exchange or healthcare integration standards
- Prior involvement in scaling engineering teams or platforms during growth phases
What We Offer
- Mission-driven work addressing critical healthcare challenges in cardiometabolic care
- Ground-floor opportunity to shape technical architecture and engineering culture
- Direct collaboration with product managers, data scientists, ML engineers, and clinical experts
- Partnership with a world-class team of venture capitalists, innovators, technologists, bioscientists, and clinicians
- Growth path into engineering leadership as the organization scales
- Competitive salary and benefits package, including participation in our equity program
About Onsera Health
We are an early-stage health AI company revolutionizing cardiometabolic care and population health economics. Our unique position within the PHP ecosystem provides:
- Venture track record: A proven track record of success in building biotech and healthcare companies
- Deep capital: Funding and resourcing to support deep tech and scientific R&D—and to drive growth
- Strategic guidance: Direct access to industry pioneers (including founders of The Medicines Company and Metsera), strategists (McKinsey/QuantumBlack alumni), and world-class scientific talent (e.g., scientific leaders at Oxford University, Ellison Institute of Technology)
- Expert network: Established connections across pharma, payers, and providers
- Startup agility: Ownership in the venture, founder mentality, and ground-floor impact
About PHP
Population Health Partners (PHP) is a premier investment firm established in 2020, aimed at transforming health outcomes for large populations. With offices in New York and London, PHP combines financial resources with industry-leading capabilities and technology. The firm's incubation portfolio includes Metsera (NASDAQ: MTSR) and Corsera Health.
Leadership: Led by industry veterans including Clive Meanwell (The Medicines Company), Chris Cox (The Medicines Company), and Whit Bernard (Metsera), bringing decades of founder experience and operational excellence in biopharma and healthcare, and Roy Berggren, 30+ year McKinsey Healthcare leader.
Principal Software Engineer - Python employer: Onsera Health
Onsera Health is an exceptional employer for Principal Software Engineers, offering a mission-driven environment that addresses critical healthcare challenges in cardiometabolic care. With a focus on innovation and collaboration, employees benefit from direct access to industry pioneers and a unique opportunity to shape technical architecture while enjoying a competitive salary and comprehensive benefits package. The company fosters a culture of growth, providing clear pathways into engineering leadership as the organization scales, making it an attractive place for those seeking meaningful and rewarding employment.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Software Engineer - Python
✨Tip Number 1
Network like a pro! Reach out to your connections in the healthcare tech space, attend meetups, and engage with industry leaders on LinkedIn. We all know that sometimes it’s not just what you know, but who you know that can land you that Principal Software Engineer role.
✨Tip Number 2
Show off your skills! Create a portfolio showcasing your projects, especially those related to healthcare integrations or AI workflows. We want to see how you’ve tackled real-world problems and delivered production-grade systems—this is your chance to shine!
✨Tip Number 3
Prepare for technical interviews by brushing up on your coding skills and system design knowledge. We recommend practicing common algorithms and architectural patterns, especially those relevant to API-first architectures and full-stack solutions. You’ve got this!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who are genuinely interested in joining our mission-driven team at Onsera Health.
We think you need these skills to ace Principal Software Engineer - Python
Some tips for your application 🫡
Tailor Your Application:Make sure to customise your CV and cover letter for the Principal Software Engineer role. Highlight your experience with Python, full-stack development, and any relevant healthcare tech projects. We want to see how your skills align with our mission!
Showcase Your Leadership Skills:Since this role involves mentoring and leading a team, don’t forget to mention your experience as a player-coach. Share examples of how you've guided engineers or contributed to team growth. We love seeing that collaborative spirit!
Be Clear and Concise:When writing your application, keep it straightforward. Use clear language to describe your achievements and technical expertise. We appreciate a well-structured application that gets straight to the point—no fluff!
Apply Through Our Website:We encourage you to submit your application directly through our website. It’s the best way for us to receive your details and ensures you’re considered for the role. Plus, it’s super easy—just a few clicks and you’re done!
How to prepare for a job interview at Onsera Health
✨Know Your Tech Inside Out
Make sure you’re well-versed in Python and the frameworks relevant to the role. Brush up on your full-stack development skills, especially around API design and integration with third-party platforms. Being able to discuss your past projects and how you tackled challenges will show your technical prowess.
✨Understand the Healthcare Landscape
Familiarise yourself with healthcare technology, especially around patient data security and compliance. Knowing about FHIR-based data exchange and healthcare interoperability patterns can set you apart. This knowledge will help you articulate how you can contribute to Onsera's mission.
✨Showcase Your Leadership Skills
As a player-coach, it’s crucial to demonstrate your ability to mentor and lead teams. Prepare examples of how you've guided engineers in the past and how you’ve contributed to building engineering standards. Highlighting your experience in scaling teams will resonate well with the interviewers.
✨Prepare for Cross-Functional Collaboration
Since this role involves working with various stakeholders, practice articulating complex technical concepts in simple terms. Be ready to discuss how you’ve successfully collaborated with product managers, data scientists, and non-technical teams in previous roles. This will show that you can bridge the gap between tech and business.
