Bioinformatician

Bioinformatician

Full-Time 50000 - 70000 £ / year (est.) Home office (partial)
Nucleus Capital I. GMBH

At a Glance

  • Tasks: Lead the development of scalable omics workflows and innovate in plant pangenome projects.
  • Company: Dynamic biotech company based in London with a focus on impactful scientific discovery.
  • Benefits: Competitive salary, equity options, 25 days leave, and remote work flexibility.
  • Other info: Join a vibrant team dedicated to innovation and professional growth.
  • Why this job: Make a real-world impact in bioinformatics while collaborating with diverse teams.
  • Qualifications: Experience with pangenomes, Nextflow, Python coding, and bioinformatics tools.

The predicted salary is between 50000 - 70000 £ per year.

This role will be based in London, with close collaboration across ML, data and scientific product. As part of the Computational Biology team, you will lead on the development of robust, scalable omics workflows that power our discovery platform, with an initial focus on plant pangenomes. You will review and evolve our existing pipelines, define how pangenomes should strengthen discovery projects, and build the computational foundations that connect public and internal omics data to downstream ML and target discovery. Working across data, ML and plant science, you will own pangenome creation and curation, drive innovation in workflows spanning gene expression and variant calling, and contribute to scientific software that is reproducible, efficient and production-ready.

Your first priorities will be to:

  • Review our existing omics pipelines, focussing on pangenomes and RNA‑seq to begin with
  • Define and implement a strategy to improve our discovery projects using pangenomes

Core responsibilities:

  • Own pangenome creation and curation
  • Own omics pipeline maintenance & curation quality
  • Drive innovation in our omics pipelines, including pangenomes, gene expression and variant calling feeding into our in‑house data warehouses for downstream ML and discovery applications
  • Work closely together with the data team to ensure seamless data onboarding and processing
  • Support public data QC and onboarding for discovery projects

Additional Responsibilities:

  • Support in‑house discovery projects
  • Help maintain and drive high standards in our scientific code base
  • Optimize resource utilisation of in‑house Nextflow workflows

Core competencies:

  • Extensive experience building and working with pangenomes in plants
  • Extensive hands‑on experience with Nextflow and omics pipelines
  • Strong coding proficiency in Python
  • High familiarity with most common omics file formats such as FASTQ, VCF, HAL, GFF
  • Familiarity with Linux environment and common bioinformatics command line tools such as seqkit, bcftools, samtools to query files quickly and effectively
  • Experience with different public omics data repositories, such as NCBI, ENSEMBL, JGI, Solgenomics etc
  • Ability to communicate clearly across disciplines. You will work daily with ML engineers, data engineers, and plant scientists, and need to translate real scientific workflows into robust software
  • Ability to understand requirements of cross‑functional teams and the ability to synthesise complex information
  • Experience working in scientific, biotech, or high‑integrity domains where reproducibility and auditability matter

Nice to have competencies:

  • Familiarity with nf‑core design principles
  • Experience with RNA‑seq mapping for pangenomes
  • Familiarity with version control; using git, GitHub, GitLab, GitBucket or similar

Benefits:

  • Competitive salary & equity options
  • 25 days annual leave & option for 2 weeks work from anywhere policy
  • Benefits package
  • Career development opportunities as the company scales
  • Ownership of ambitious, mission‑driven work with real‑world impact
  • Vibrant, innovative & supportive work environment with a committed team
  • Access to conferences, events & professional development resources

Bioinformatician employer: Nucleus Capital I. GMBH

Join a vibrant and innovative team in London as a Bioinformatician, where you'll have the opportunity to lead the development of cutting-edge omics workflows that drive real-world impact. With a competitive salary, generous annual leave, and a supportive work culture that prioritises professional growth, you'll collaborate closely with experts across data, machine learning, and plant science, ensuring your contributions are both meaningful and rewarding. Embrace the chance to own ambitious projects in a dynamic environment that values creativity and collaboration.
Nucleus Capital I. GMBH

Contact Detail:

Nucleus Capital I. GMBH Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Bioinformatician

✨Network Like a Pro

Get out there and connect with folks in the bioinformatics scene! Attend meetups, conferences, or even online webinars. The more people you know, the better your chances of hearing about job openings before they hit the market.

✨Show Off Your Skills

Don’t just tell them what you can do; show them! Create a portfolio showcasing your work with pangenomes and omics pipelines. Share your projects on GitHub or similar platforms to demonstrate your coding chops and problem-solving skills.

✨Tailor Your Approach

When reaching out to potential employers, make sure to tailor your message to their specific needs. Highlight your experience with Nextflow and your familiarity with omics data formats. Show them you understand their challenges and how you can help!

✨Apply Through Our Website

We’ve got some exciting opportunities waiting for you! Make sure to apply through our website to get the best chance at landing that dream role. It’s the easiest way for us to see your application and get you in the door.

We think you need these skills to ace Bioinformatician

Pangenome Creation and Curation
Nextflow
Omics Pipelines
Python Programming
Omics File Formats (FASTQ, VCF, HAL, GFFF)
Linux Environment
Bioinformatics Command Line Tools (seqkit, bcftools, samtools)
Public Omics Data Repositories (NCBI, ENSEMBL, JGI, Solgenomics)
Cross-Disciplinary Communication
Complex Information Synthesis
Scientific Software Development
Reproducibility and Auditability Standards
RNA-seq Mapping
Version Control (git, GitHub, GitLab, GitBucket)

Some tips for your application 🫡

Tailor Your CV: Make sure your CV is tailored to the Bioinformatician role. Highlight your experience with pangenomes, omics pipelines, and any relevant coding skills in Python. We want to see how your background aligns with our needs!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about bioinformatics and how you can contribute to our team. Be sure to mention specific projects or experiences that relate to our work at StudySmarter.

Showcase Your Technical Skills: Don’t forget to highlight your technical skills, especially your experience with Nextflow and various omics file formats. We’re looking for someone who can hit the ground running, so make those skills pop in your application!

Apply Through Our Website: We encourage you to apply through our website for the best chance of getting noticed. It’s the easiest way for us to keep track of your application and ensure it reaches the right people. Good luck!

How to prepare for a job interview at Nucleus Capital I. GMBH

✨Know Your Pangenomes

Make sure you brush up on your knowledge of pangenomes, especially in plants. Be ready to discuss your experience with building and curating them, as well as how they can enhance discovery projects. This will show that you understand the core responsibilities of the role.

✨Showcase Your Coding Skills

Prepare to demonstrate your coding proficiency in Python. You might be asked to solve a problem or explain your approach to coding challenges related to omics pipelines. Practising common bioinformatics command line tools will also help you feel more confident during technical discussions.

✨Familiarise Yourself with Nextflow

Since this role involves maintaining and innovating omics pipelines using Nextflow, make sure you’re comfortable discussing your experience with it. If you have worked with nf-core design principles, be ready to share specific examples of how you've applied them in your previous work.

✨Communicate Across Disciplines

This position requires collaboration with ML engineers, data engineers, and plant scientists. Prepare to discuss how you’ve effectively communicated complex scientific workflows to non-experts in the past. Highlighting your ability to synthesise information for cross-functional teams will set you apart.

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