Senior Clinical Trial Leader - Translational Medicine

Senior Clinical Trial Leader - Translational Medicine

Full-Time 60000 - 80000 £ / year (est.) No working from home possible
Novartis

At a Glance

  • Tasks: Lead global early-phase clinical trials and ensure high-quality study delivery.
  • Company: Join Novartis, a leader in innovative healthcare solutions.
  • Benefits: Flexible remote work, competitive salary, and opportunities for professional growth.
  • Other info: Dynamic team environment with a commitment to diversity and inclusion.
  • Why this job: Make a real impact on patient lives through groundbreaking clinical research.
  • Qualifications: 6+ years in clinical trials with strong leadership and collaboration skills.

The predicted salary is between 60000 - 80000 £ per year.

We are seeking a Senior Clinical Sciences Trial Leader to join Clinical Sciences & Innovation (CSI) – Translational Medicine in our London office. This is a senior role with responsibility for the scientific and operational leadership of complex, global early phase clinical trials, from first in human through to early proof of concept.

As a Senior Trial Leader, you will be accountable for the design, planning and delivery of high quality clinical studies, leading global cross functional trial teams and ensuring robust, interpretable data to support key portfolio decisions. You will work closely with Medical Leads and functional partners, taking ownership of study level decisions and execution in a fast paced, scientifically driven environment.

This role is well suited to an experienced Trial Leader who thrives as a hands on study leader, enjoys building strong, effective teams around their studies, and is motivated to continue growing their own capabilities while positively influencing how colleagues work together. This position is based at the Westworks London office, with flexibility to work remotely for up to two days a week. Domestic and international travel may be required to support investigator meetings, study team engagement and trial oversight.

Key Responsibilities

  • Provide scientific and operational leadership for assigned global early‑phase clinical trials, with a focus on medium‑ to high‑complexity studies.
  • Accountable for end‑to‑end study delivery from study design through to final reporting.
  • Independently lead the clinical protocol development process, serving as author for protocols and related documents in close collaboration with Medical Leads and cross‑functional partners.
  • Drive study feasibility assessment and operational execution planning to ensure studies are scientifically robust and operationally deliverable.
  • Lead and coordinate global, cross‑functional Clinical Trial Teams (CTTs), fostering effective collaboration and alignment across functions and geographies.
  • Forecast and manage study budgets in partnership with functional colleagues and vendors.
  • Lead the ongoing scientific and medical review of clinical trial data, including safety trend analysis, signal detection and interpretation of emerging results.
  • Contribute to Clinical Study Reports (CSRs), internal decision documents, publications and external scientific communications.
  • Share lessons learned and contribute to continuous improvement of trial delivery and ways of working within CSI and Translational Medicine.
  • Act as a positive role model within study teams, supporting effective team dynamics, knowledge sharing and high standards of scientific and operational excellence.

Expected Prior Experience / Competencies

  • Bachelor’s degree in life sciences or healthcare required; advanced degree (MSc, PhD, PharmD, MD or equivalent) preferred.
  • Demonstrated experience acting as Clinical Scientist or Study Leader for global clinical trials, with ~6+ years’ experience in clinical trials and/or development.
  • Strong experience in protocol development, study design and clinical data interpretation, with the ability to operate across therapeutic areas.
  • Proven ability to lead and influence study teams in a matrix environment, building strong working relationships and driving delivery through collaboration.
  • Comfortable operating with a high degree of personal ownership and accountability, navigating ambiguity and making informed study‑level decisions.
  • A clear growth mindset, with interest in developing own capabilities and contributing positively to team effectiveness and the wider CSI culture.
  • Solid understanding of ICH‑GCP, regulatory requirements and high‑quality clinical trial conduct.

Commitment To Diversity & Inclusion

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives.

Ready to create a brighter future together?

Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.

Senior Clinical Trial Leader - Translational Medicine employer: Novartis

At Novartis, we pride ourselves on being an exceptional employer, offering a dynamic work culture that fosters collaboration and innovation in our London office. As a Senior Clinical Trial Leader, you will benefit from flexible working arrangements, opportunities for professional growth, and the chance to lead impactful clinical trials that contribute to groundbreaking advancements in healthcare. Join us in a supportive environment where your expertise is valued, and together, we can make a difference in the lives of patients worldwide.

Novartis

Contact Details:

Novartis Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Senior Clinical Trial Leader - Translational Medicine

Tip Number 1

Network like a pro! Reach out to your connections in the industry, attend relevant events, and engage with professionals on platforms like LinkedIn. We all know that sometimes it’s not just what you know, but who you know that can help you land that dream role.

Tip Number 2

Prepare for interviews by researching the company and its culture. Understand their values and how they align with your own. We want you to shine, so practice common interview questions and think about how your experience as a Trial Leader can add value to their team.

Tip Number 3

Showcase your leadership skills! During interviews, share specific examples of how you've successfully led clinical trials and built effective teams. We love hearing about your hands-on approach and how you’ve navigated challenges in a fast-paced environment.

Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, we’re always looking for passionate individuals who are ready to make a difference in the world of clinical trials.

We think you need these skills to ace Senior Clinical Trial Leader - Translational Medicine

Scientific Leadership
Operational Leadership
Clinical Protocol Development
Study Design
Clinical Data Interpretation
Cross-Functional Team Coordination
Budget Management

Some tips for your application 🫡

Tailor Your CV:Make sure your CV reflects the specific skills and experiences that match the Senior Clinical Trial Leader role. Highlight your experience in leading clinical trials and any relevant achievements that showcase your ability to drive study delivery.

Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to tell us why you're passionate about Translational Medicine and how your background makes you the perfect fit for our team. Be sure to mention your leadership style and how you foster collaboration.

Showcase Your Scientific Expertise:In your application, don’t forget to highlight your scientific knowledge and operational leadership in clinical trials. We want to see how you've contributed to protocol development and data interpretation in your previous roles.

Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it shows us you’re serious about joining our team at Novartis!

How to prepare for a job interview at Novartis

Know Your Trials Inside Out

Before the interview, dive deep into the specifics of early-phase clinical trials. Familiarise yourself with the latest trends in translational medicine and be ready to discuss how your experience aligns with the responsibilities outlined in the job description.

Showcase Your Leadership Skills

Prepare examples that highlight your ability to lead cross-functional teams effectively. Think about times when you’ve navigated challenges in a matrix environment and how you fostered collaboration among diverse team members.

Be Ready for Technical Questions

Expect questions on protocol development and data interpretation. Brush up on ICH-GCP guidelines and be prepared to discuss how you ensure high-quality trial conduct. This will demonstrate your technical expertise and commitment to excellence.

Emphasise Your Growth Mindset

During the interview, express your enthusiasm for continuous learning and improvement. Share specific instances where you’ve sought feedback or taken initiative to enhance team dynamics, showing that you’re not just a leader but also a team player.