At a Glance
- Tasks: Lead biomarker strategies from target validation to early clinical planning in innovative projects.
- Company: Join Novartis, a leader in biomedical research with a collaborative culture.
- Benefits: Enjoy competitive salary, flexible working options, and comprehensive wellbeing resources.
- Other info: Be part of a diverse team committed to reimagining medicine together.
- Why this job: Make a real impact on patient lives through groundbreaking biomarker strategies.
- Qualifications: PhD or equivalent with 7+ years in translational research or drug development.
The predicted salary is between 10000 - 211900 £ per year.
Novartis Biomedical Research is seeking a highly motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic advisor on DAx project teams. This role will lead the development and execution of preclinical and translational biomarker strategies from target validation through development candidate nomination and early clinical planning. The Biomarker Strategy Lead will partner closely with Biology, In Vitro, In Vivo, Data Science and Biomarker Development to ensure biomarker plans are aligned with key program decisions and support target engagement, pharmacodynamic assessment, patient stratification, and translational decision-making. The successful candidate will act as the single point of contact for biomarker strategy within assigned DAx programs, integrating scientific, technical, operational, and external capabilities to deliver execution-ready biomarker plans that enable efficient progression of the portfolio.
Major accountabilities:
- Lead development of stage-appropriate preclinical and translational biomarker strategies for DAx programs from target validation through early clinical development readiness.
- Serve as the biomarker representative and single point of contact on assigned DAx project teams.
- Define biomarker hypotheses, context of use, evidence requirements, and decision criteria aligned with program milestones.
- Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships.
- Partner across Biology, In Vitro, In Vivo, Data Science, Preclinical Safety, Quantitative Sciences, Translational Medicine, and Biomarker Development to align biomarker activities and execution.
- Generate translational evidence linking target biology, pharmacology, and biomarkers to support key portfolio decisions.
- Drive external collaborations and leverage innovative technologies, datasets, and human sample resources to strengthen biomarker strategies and research-to-development transition.
Minimum Qualifications:
- PhD, MD, PharmD, or equivalent in biology, pharmacology, immunology, translational medicine, molecular biology, or related discipline.
- 7+ years of experience in translational research, biomarker strategy, biomarker discovery, or drug development within the pharmaceutical or biotechnology industry.
- Demonstrated experience developing biomarker strategies supporting drug discovery and development programs.
- Strong understanding of biomarker applications including target engagement, pharmacodynamics, patient stratification, disease activity, and mechanism-based biomarkers.
- Experience leading cross-functional matrix teams and influencing scientific strategy without direct authority.
- Excellent communication, presentation, and stakeholder management skills.
Rewards:
At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen. The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks paid parental leave.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and reasonable accommodations:
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Principal Scientist II, Translational Biomarker Strategy Lead employer: Novartis
At Novartis, we pride ourselves on being an exceptional employer that fosters a collaborative and innovative work culture. Our hybrid work model allows for flexibility while providing ample opportunities for professional growth and development in the pharmaceutical industry. With a commitment to enhancing customer experiences for healthcare professionals and patients alike, joining our team means contributing to meaningful work that makes a difference in people's lives.
