At a Glance
- Tasks: Design and execute in-vitro ADME assays to support drug discovery.
- Company: Join a leading biotech firm focused on innovative drug development.
- Benefits: Competitive salary, comprehensive health benefits, and generous time off.
- Other info: Dynamic team environment with opportunities for career growth.
- Why this job: Make a real impact in drug discovery with cutting-edge lab automation.
- Qualifications: BSc or MSc in relevant field with 4-7 years of experience.
The predicted salary is between 54000 - 66000 £ per year.
Support discovery and development projects through the design, development, and execution of in-vitro ADME assays, while building next generation lab automation capabilities to deliver high-quality study data for informed decision-making.
Key Responsibilities:
- Plan, execute and report ADME assays such as metabolic stability and permeability to support PK Science’s strategies.
- Interpret in vitro ADME data and translate findings to support early discovery, compound optimization and selection.
- Contribute to novel ADME methodologies and expand assay capabilities.
- Advance automation strategies (e.g., liquid handling, assay miniaturization, assay multiplexing) to expand laboratory capacity, standardize execution to reduce manual effort, and strengthen discovery assay operations.
- Execute and/or contribute to fully automated, end-to-end ADME assay workflows integrated with AI-enabled analytics.
- Develop methods to support small and large molecule bio-analysis using LCMS-MS, HRMS, and ICP-MS techniques.
- Troubleshoot lab instrumentation and automation platforms.
- Manage study timelines, objectives and budgets, ensure accuracy of project progress in company tracking tools.
- Under management supervision, work to effectively communicate data, strategy and results to the project teams.
- Contribute to internal ADME study reports and regulatory documents (IND, IMPD, NDA, etc.).
- Participate in cross-departmental teams, department-wide initiatives and work streams.
- Complete all required organizational trainings and requirements according to corporate timelines.
- Adhere in strict accord to the appropriate SOP, quality and HSE guidelines.
Essential Requirements:
- BSc or MSc with relevant experience in drug metabolism and pharmacokinetics or related field.
- BSc: 7+ years; MSc: 4+ years of ADME/DMPK experience.
- Experience working in a drug discovery or development laboratory or relevant experience in a CRO, Pharma or Biotech is highly desirable.
- Experience in metabolic stability and permeability assays highly preferable; cell culture experience is a plus.
- Experience with laboratory automation integrated with AI-enabled analytics is highly desirable.
- Knowledge of related disciplines (e.g., bioanalytical, toxicology, biomarker) in the drug discovery or development process.
- Ability to work as part of a cross-functional team in a highly dynamic, matrixed, project-team environment.
- Strong organizational and project skills with critical thinking and problem-solving skills.
- Fluent oral and written English.
The salary for this position is expected to range between $89,600 and $166,400 per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
EEO Statement: The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility and reasonable accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Senior Scientist I- Translational Medicine- PKS, ADME in Cambridge employer: Novartis
At Novartis, we pride ourselves on being an exceptional employer that fosters a collaborative and innovative work culture. Our hybrid work model allows for flexibility while providing ample opportunities for professional growth and development in the pharmaceutical industry. With a commitment to enhancing customer experiences for healthcare professionals and patients alike, joining our team means contributing to meaningful work that makes a difference in people's lives.
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We think this is how you could land Senior Scientist I- Translational Medicine- PKS, ADME in Cambridge
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We think you need these skills to ace Senior Scientist I- Translational Medicine- PKS, ADME in Cambridge
Some tips for your application 🫡
Showcase Your Relevant Experience:When applying for a role in the pharmaceutical industry, it's crucial to highlight any relevant experience you have. Whether that's internships, lab work, or even related coursework, make sure to weave this into your CV and cover letter. We want to see how your background aligns with the role you're applying for at Novartis!
Emphasise Your Understanding of Regulations:The pharmaceutical industry is heavily regulated, so it's important to indicate your familiarity with industry standards and regulations. In your cover letter, mention any training or certifications you've received that are relevant, or discuss projects where you’ve navigated compliance. This will show Novartis that you're not just a fit for the job but also a safety-conscious candidate!
Tailor Your CV to Be Result-Driven:Craft your CV to highlight quantifiable achievements, especially if you have previous roles in pharmaceuticals or related fields. Use metrics to demonstrate your impact, such as improved processing times or successful project completions while working on trials. This analytical approach will resonate well with hiring managers at Novartis!
Convey Your Passion for the Industry:In your cover letter, express why you are passionate about working in the pharmaceutical sector. Whether it’s your desire to contribute to groundbreaking drug research or improve patient outcomes, let it shine through! At Novartis, we value candidates who are truly enthusiastic about their work—you might just stand out from the crowd.
How to prepare for a job interview at Novartis
✨Understand the Science
Make sure you brush up on key pharmaceutical concepts and recent developments in the industry. You might get asked some technical questions during the interview at Novartis that show your grasp of drug development processes or regulatory requirements, so be ready to discuss them clearly.
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If you have any hands-on experience or internships in a laboratory setting, be sure to highlight these in your responses. Think about the projects you worked on, the methodologies you used, and the impact you made. It's all about telling a story that connects your background to the role you're applying for.
✨Know Their Products
Take some time to familiarise yourself with Novartis’s product range and recent breakthroughs. Understanding their portfolio not only shows your enthusiasm for the role but also allows you to ask insightful questions that demonstrate your interest in actively contributing to their projects.
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In a full-time pharmaceutical role, understanding the regulatory landscape is crucial. Prepare for situational questions that may test your problem-solving skills concerning compliance and safety standards. You could be asked how you'd handle a hypothetical issue regarding a drug’s market release, so think through your approach.
