Overview
In this role you will lead the development and execution of AI-driven strategies to transform clinical pharmacology support for new medicines. You will drive AI-based applications to accelerate PKS deliverables and enable cross-functional, translational workflows. You work closely with PKS, ADME/BA, M&S, and clinical teams to integrate pharmacokinetic insights into study design and regulatory documents. This is a hands-on, impact‑driven role at the intersection of translational medicine and data science, offering the opportunity to shape how AI accelerates drug development at Novartis.
Pay / Benefits
- health, life and disability benefits
- 401(k) with company contribution and match
- generous time-off package
- annual incentive eligibility
- comprehensive benefits package for US-based employees
- vacation, personal days, holidays and other leaves
Responsibilities
- Lead the AI strategy for clinical pharmacology within PKS and oversee its implementation.
- Demonstrate AI/digital fluency and leverage enterprise tools to support strategic, scientific, and operational leadership in clinical pharmacology.
- Identify and develop high-value AI use cases to improve planning, analyses, and decision quality in clinical pharmacology.
- Represent the PK Sciences function in project teams and regulatory interactions as appropriate.
- Provide expert PK/PD input across Drug Discovery, Development, and Commercial continuum to support candidate progression.
- Collaborate with teams to use AI to accelerate understanding of PK/PD relationships and inform dosing strategies.
- Drive use of AI to enhance study protocols, reports, and development plans, including pharmacokinetic sections of regulatory submissions and responses.
- Foster close interdisciplinary collaboration among PKS, ADME/BA, M&S, and operations through PK science sub-teams.
- Work with clinicians to integrate PKS insights into study design, data interpretation, and decision-making.
- Model AI/ML approaches to enable data automation and regulatory document authoring in PKS contexts.
Key requirements
- Ph.D. or Pharm.D. with relevant PK/PM knowledge
- 8–10 years of drug discovery/development experience
- 6+ years in ADME/DMPK translational/clinical development or AI strategy
- Extensive PK knowledge (PK/PD, drug metabolism) and cross-functional project experience
- Experience in a global, matrixed project-team environment
- Strong oral and written communication skills
- Cross-functional collaboration
- Strategic thinking
- Communication
- Artificial intelligence / machine learning approaches
- Pharmacokinetics, drug metabolism, PK/PD evaluation
- Regulatory science awareness
Director, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead in Cambridge employer: Novartis
Novartis is an exceptional employer that fosters a collaborative and inclusive work environment, where passionate individuals come together to drive breakthroughs in precision medicine. With competitive salaries, flexible working arrangements, and robust learning and development opportunities, employees are empowered to grow both personally and professionally while making a meaningful impact on patients' lives. Located in vibrant cities like London, Barcelona, and Dublin, Novartis offers a dynamic workplace that values diversity and encourages innovation.
