Overview
In this strategic leadership role, you steer the chemistry strategy for antibody-drug conjugate and vectorized drug conjugate programs in oncology. You will lead a team of medicinal chemists, shape portfolio priorities, and foster cross-functional partnerships to translate science into patient-focused therapies. You’ll drive breakthrough chemistry approaches, manage complex programs from discovery to development milestones, and advocate an inclusive, innovative culture. This is a mission-driven opportunity to influence next-generation oncology modalities at Novartis.
Pay / Benefits
- flexible and hybrid working options
- minimum 14 weeks paid parental leave
- insurance plans
- retirement plans
- wellbeing resources
- global recognition programs
Responsibilities
- Lead medicinal chemistry strategy for ADC and vectorized drug conjugate programs across the oncology portfolio
- Guide project teams from exploratory research to candidate nomination
- Build, mentor and develop a high-performing team of medicinal chemists
- Partner with biology, biotherapeutics, PK, safety, and process chemistry to advance programs
- Shape portfolio strategy, prioritization and resourcing aligned with oncology goals
- Identify emerging technologies, external collaborations and opportunities to strengthen the discovery portfolio
- Foster an innovative, inclusive and collaborative environment amid complexity and change
Key requirements
- Doctoral degree in Organic Chemistry, Medicinal Chemistry or closely related discipline
- Minimum 12 years of pharma/biotech R&D experience with significant leadership experience
- Proven success advancing oncology drug discovery toward clinical development
- Deep knowledge of antibody-drug conjugates and vectorized drug conjugates
- Broad understanding of drug discovery disciplines including PK, toxicology and pharmacology
- Demonstrated ability to lead multidisciplinary teams, influence across functions, and translate science into strategic decisions
- Strategic leadership
- Cross-functional collaboration
- People development
- Antibody-drug conjugates (ADCs) and vectorized drug conjugates
- Medicinal chemistry and lead optimization
- Structure-activity relationships (SAR)
Director, GDC Head of ADC Oncology Chemistry in Cambridge employer: Novartis
Novartis is an exceptional employer that fosters a collaborative and inclusive work environment, where passionate individuals come together to drive breakthroughs in precision medicine. With competitive salaries, flexible working arrangements, and robust learning and development opportunities, employees are empowered to grow both personally and professionally while making a meaningful impact on patients' lives. Located in vibrant cities like London, Barcelona, and Dublin, Novartis offers a dynamic workplace that values diversity and encourages innovation.
