Find a job 
Featured Companies 
Featured Universities 
For Companies At a Glance
- Tasks: Lead innovative research in CAR-T and TCR cell therapy development.
- Company: Join a dynamic biotech company at the forefront of immuno-oncology.
- Benefits: Collaborative environment, impactful work, and opportunities for mentorship.
- Why this job: Make a real difference in next-gen cancer therapies while working with passionate scientists.
- Qualifications: PhD in relevant field or significant biotech experience; hands-on CAR-T/TCR expertise required.
- Other info: On-site role based in Oxford; ideal for those eager to innovate.
The predicted salary is between 36000 - 60000 £ per year.
Overview:
We are seeking an exceptional Scientist with a passion for immuno-oncology and hands-on expertise in CAR-T and TCR cell therapy discovery and development. This is a dynamic, lab-based role based at our Oxford site, where you will lead experimental design, execute in vitro functional assays, and collaborate cross-functionally to advance innovative cell therapies toward the clinic.
This position offers an exciting opportunity to contribute directly to the design and optimisation of novel CAR-T constructs within a fast-paced, collaborative biotech environment.
Key Responsibilities:
- Lead the design, development, and execution of in vitro functional assays to evaluate CAR-T/TCR activity, including cytotoxicity, cytokine release, and target engagement.
- Develop, optimise, and troubleshoot protocols for CAR construct screening and primary T cell engineering.
- Design and perform multiparameter flow cytometry experiments; analyse and interpret complex immunophenotyping data.
- Develop and validate ELISA and Western blot assays to support functional and mechanistic studies.
- Generate actionable insights from experimental data to guide CAR/TCR construct selection and refinement.
- Collaborate closely with bioinformatics, translational, and cell engineering teams to integrate data and align project goals.
- Prepare scientific presentations, technical reports, and contribute to regulatory documentation as needed.
- Stay abreast of emerging trends in CAR-T/TCR research and immuno-oncology; implement innovative approaches in R&D.
- Mentor junior scientists and foster a culture of scientific rigor, curiosity, and innovation.
Qualifications:
- PhD in Immunology, Molecular Biology, Cell Biology, or related discipline is required for Scientist level
- Hands-on expertise in CAR-T/TCR development, T cell engineering, or immune cell therapy.
- Strong practical knowledge of multiparameter flow cytometry, ELISA, Western blot, assay development, and primary immune cell culture.
- Proven ability to analyse complex datasets and extract meaningful biological insights.
- Excellent scientific communication skills, both written and verbal.
- Ability to work independently and collaboratively in a fast-paced, team-oriented environment.
- Must be able to work on-site at our Oxford facility.
Why Join Us?
- Contribute to groundbreaking advances in next-generation cell therapy innovation.
- Work within a mission-driven, supportive, and collaborative scientific team.
- Opportunity to make a tangible impact on the future of immuno-oncology therapies.
If you are passionate about driving CAR-T/TCR therapy development and thrive in a fast-moving, impactful environment, and are able to work at our Oxford site, we encourage you to apply.
Scientist employer: Northreach
Contact Detail:
Northreach Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist
✨Tip Number 1
Familiarise yourself with the latest advancements in CAR-T and TCR therapies. Being well-versed in current research and trends will not only enhance your understanding but also demonstrate your passion for the field during interviews.
✨Tip Number 2
Network with professionals in the immuno-oncology space. Attend relevant conferences, webinars, or local meetups to connect with industry experts and gain insights that could give you an edge in discussions with our team.
✨Tip Number 3
Prepare to discuss your hands-on experience with specific techniques mentioned in the job description, such as flow cytometry and ELISA. Be ready to share examples of how you've successfully applied these methods in your previous work.
✨Tip Number 4
Showcase your collaborative spirit by thinking of examples where you've worked cross-functionally in past roles. Highlighting your ability to integrate data and align project goals will resonate well with our team-oriented culture.
We think you need these skills to ace Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in immunology, CAR-T/TCR development, and any hands-on expertise you have. Use specific examples to demonstrate your skills in assay development and data analysis.
Craft a Compelling Cover Letter: In your cover letter, express your passion for immuno-oncology and detail why you are excited about the opportunity at this company. Mention how your background aligns with their mission and the specific responsibilities of the role.
Highlight Collaborative Experience: Since the role involves cross-functional collaboration, emphasise any previous experiences where you worked effectively in a team. Showcase your ability to communicate complex scientific concepts clearly to diverse audiences.
Showcase Continuous Learning: Mention any recent courses, workshops, or conferences you’ve attended related to CAR-T/TCR research or immuno-oncology. This demonstrates your commitment to staying updated with emerging trends in the field.
How to prepare for a job interview at Northreach
✨Showcase Your Expertise
Be prepared to discuss your hands-on experience with CAR-T and TCR cell therapies in detail. Highlight specific projects you've worked on, the challenges you faced, and how you overcame them. This will demonstrate your practical knowledge and problem-solving skills.
✨Prepare for Technical Questions
Expect questions related to immunology, molecular biology, and assay development. Brush up on multiparameter flow cytometry, ELISA, and Western blot techniques. Being able to explain complex concepts clearly will show your depth of understanding.
✨Demonstrate Collaborative Spirit
Since the role involves cross-functional collaboration, be ready to share examples of how you've successfully worked with other teams in the past. Emphasise your ability to integrate data and align project goals with colleagues from different disciplines.
✨Stay Current with Trends
Research the latest advancements in CAR-T/TCR research and immuno-oncology. Being knowledgeable about emerging trends will not only impress your interviewers but also show your passion for the field and commitment to innovation.
