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For Companies At a Glance
- Tasks: Lead innovative research in CAR-T and TCR cell therapy development.
- Company: Join a dynamic biotech company at the forefront of immuno-oncology.
- Benefits: Collaborative environment, impactful work, and opportunities for mentorship.
- Why this job: Make a real difference in next-gen cancer therapies while working with passionate scientists.
- Qualifications: PhD in relevant field or significant biotech experience; hands-on CAR-T/TCR expertise required.
- Other info: On-site role based in Oxford; ideal for those eager to innovate.
The predicted salary is between 36000 - 60000 £ per year.
About the Job
Northreach is a specialist life science recruitment partner, connecting pioneering biotech and biopharma companies with exceptional scientific talent. We partner with businesses that are shaping the future of medicine and empower candidates to take the next step in their scientific careers.
One of our innovative biotech clients is seeking a Senior RA/Scientist – CAR-T Cell Therapy to join their growing R&D team in Oxford, UK. This full-time, permanent position offers the opportunity to contribute to the development of next-generation CAR-T cell therapies designed to tackle solid tumours and other high-value oncology indications.
The ideal candidate will have recently completed a PhD in CAR-T research, immuno-oncology, or a related field and will be eager to apply their academic expertise to real-world therapeutic development in a dynamic, fast-paced environment.
The Role
- Design and execute in vitro functional assays (e.g. cytotoxicity, cytokine release, proliferation) to assess CAR-T activity.
- Culture and expand primary human T cells using aseptic techniques.
- Develop and validate flow cytometry panels for immunophenotyping.
- Support high-throughput screening of CAR constructs for potency and specificity.
- Maintain detailed electronic lab records and ensure data integrity.
- Analyse and present results to cross-functional R&D teams.
- Collaborate with scientists and engineers across discovery, translational, and process development functions.
- Contribute to lab operations, SOP development, and mentoring of junior staff.
The Profile
- PhD in Immunology, Cell Biology, or related field with research focused on CAR-T, T cell engineering, or immuno-oncology.
- Hands-on experience with mammalian cell culture and immunological assays.
- Skilled in flow cytometry and data analysis tools (FlowJo, GraphPad Prism).
- Strong experimental design, troubleshooting, and analytical skills.
- Excellent communicator with meticulous attention to detail.
Why Apply
This is an exceptional opportunity for a recently qualified PhD scientist to translate cutting-edge CAR-T research into meaningful clinical applications. You’ll join a pioneering biotech at the forefront of cell therapy innovation, working alongside world-class scientists to help shape the next generation of cancer immunotherapies.
Scientist employer: Northreach
Contact Detail:
Northreach Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Scientist
✨Tip Number 1
Familiarise yourself with the latest advancements in CAR-T and TCR therapies. Being well-versed in current research and trends will not only enhance your understanding but also demonstrate your passion for the field during interviews.
✨Tip Number 2
Network with professionals in the immuno-oncology space. Attend relevant conferences, webinars, or local meetups to connect with industry experts and gain insights that could give you an edge in discussions with our team.
✨Tip Number 3
Prepare to discuss your hands-on experience with specific techniques mentioned in the job description, such as flow cytometry and ELISA. Be ready to share examples of how you've successfully applied these methods in your previous work.
✨Tip Number 4
Showcase your collaborative spirit by thinking of examples where you've worked cross-functionally in past roles. Highlighting your ability to integrate data and align project goals will resonate well with our team-oriented culture.
We think you need these skills to ace Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in immunology, CAR-T/TCR development, and any hands-on expertise you have. Use specific examples to demonstrate your skills in assay development and data analysis.
Craft a Compelling Cover Letter: In your cover letter, express your passion for immuno-oncology and detail why you are excited about the opportunity at this company. Mention how your background aligns with their mission and the specific responsibilities of the role.
Highlight Collaborative Experience: Since the role involves cross-functional collaboration, emphasise any previous experiences where you worked effectively in a team. Showcase your ability to communicate complex scientific concepts clearly to diverse audiences.
Showcase Continuous Learning: Mention any recent courses, workshops, or conferences you’ve attended related to CAR-T/TCR research or immuno-oncology. This demonstrates your commitment to staying updated with emerging trends in the field.
How to prepare for a job interview at Northreach
✨Showcase Your Expertise
Be prepared to discuss your hands-on experience with CAR-T and TCR cell therapies in detail. Highlight specific projects you've worked on, the challenges you faced, and how you overcame them. This will demonstrate your practical knowledge and problem-solving skills.
✨Prepare for Technical Questions
Expect questions related to immunology, molecular biology, and assay development. Brush up on multiparameter flow cytometry, ELISA, and Western blot techniques. Being able to explain complex concepts clearly will show your depth of understanding.
✨Demonstrate Collaborative Spirit
Since the role involves cross-functional collaboration, be ready to share examples of how you've successfully worked with other teams in the past. Emphasise your ability to integrate data and align project goals with colleagues from different disciplines.
✨Stay Current with Trends
Research the latest advancements in CAR-T/TCR research and immuno-oncology. Being knowledgeable about emerging trends will not only impress your interviewers but also show your passion for the field and commitment to innovation.
