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- Tasks: Drive small molecule drug discovery using mass spectrometry in a lab-based role.
- Company: Join a leading Global Biopharma with innovative research projects.
- Benefits: Competitive salary, hands-on experience, and collaborative work environment.
- Why this job: Make a real impact in drug discovery and work with cutting-edge technology.
- Qualifications: Ph.D. or equivalent experience in small molecule mass spectrometry required.
- Other info: Fast-paced, team-oriented environment with opportunities for professional growth.
The predicted salary is between 36000 - 60000 £ per year.
A 12-month contract opportunity for a Senior Research Scientist to join our client, a leading Global Biopharma, working on cutting-edge research to drive small molecule drug discovery using mass spectrometry. This will be a fully lab-based role, working from early stage through to preclinical projects, and will play a pivotal role in developing and delivering mass spectrometry (MS)-based assays to support the optimization of small molecule ligands as part of the drug discovery process.
Key Responsibilities:
- Design, develop, and validate robust small molecule MS-based assays to support drug discovery and development programs.
- Optimize assay conditions to ensure high sensitivity, specificity, and reproducibility for small molecule detection and quantification.
- Collaborate with structural biology and biophysics teams to integrate MS data with structural and biophysical insights.
- Work closely with medicinal chemists, biologists, and other scientists to align assay development with project goals.
- Communicate results effectively through presentations, reports, and publications.
- Ensure compliance with laboratory SOPs, and detailed record keeping in electronic notebook.
- Maintain, operate and troubleshoot LCMS instrumentation for routine and novel assays.
Qualifications:
- Relevant Ph.D. or equivalent experience with proven track record of small molecule mass spec delivery.
- Experience running and analysing quantitative small molecule mass spec assays.
- Practical experience working with triple quad MS platforms.
- Hands-on experience troubleshooting complex instrumentation.
- Track record for scientific problem solving.
- Sound understanding of data analysis principles and familiarity with data analysis software packages with particular focus on small molecule MS analysis.
- Self-driven ability to organize resources and data, manage time and priorities.
- Desire to work in a fast, collaborative, and team-oriented environment.
- The ability to communicate clear and concise updates across a variety of audience levels, keep track of experimental records and results.
- Experience with data organisation and downstream reporting of MS data to other disciplines e.g. medicinal chemistry.
- Demonstrated ability to work as part of a multidisciplinary team.
- Experience of small molecule Affinity Selection Mass Spectrometry (AS-MS).
- Experience in biochemical, biophysical, bioanalytical, and/or cellular MS screening technologies.
- Familiarity with other protein MS techniques such as Intact Mass, Native, HDX.
- Experience of working within the drug discovery industry.
For more information or a confidential discussion, please apply now!
Senior Research Scientist – Mass Spectrometry in Oxford employer: Nicholas Howard Ltd.
Contact Detail:
Nicholas Howard Ltd. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Research Scientist – Mass Spectrometry in Oxford
✨Tip Number 1
Network like a pro! Reach out to your connections in the biopharma industry, especially those who work with mass spectrometry. A friendly chat can lead to insider info about job openings or even a referral.
✨Tip Number 2
Prepare for interviews by brushing up on your technical skills and recent advancements in mass spectrometry. We want you to showcase your expertise and passion for small molecule drug discovery!
✨Tip Number 3
Don’t underestimate the power of follow-ups! After an interview, drop a quick thank-you email to express your appreciation and reiterate your enthusiasm for the role. It keeps you fresh in their minds.
✨Tip Number 4
Apply through our website for a smoother process! We’ve got all the resources you need to make your application stand out, so don’t miss out on this opportunity to join a leading global biopharma.
We think you need these skills to ace Senior Research Scientist – Mass Spectrometry in Oxford
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Senior Research Scientist role. Highlight your experience with mass spectrometry and any relevant projects you've worked on. We want to see how your skills align with our needs!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about drug discovery and how your background makes you a perfect fit for our team. Keep it concise but impactful!
Showcase Your Collaboration Skills: Since this role involves working closely with various teams, make sure to mention any collaborative projects you've been part of. We love seeing how you can work in a multidisciplinary environment!
Apply Through Our Website: Don't forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for the role. We can't wait to hear from you!
How to prepare for a job interview at Nicholas Howard Ltd.
✨Know Your Mass Spectrometry Inside Out
Make sure you brush up on your knowledge of mass spectrometry, especially the techniques and platforms mentioned in the job description. Be ready to discuss your hands-on experience with triple quad MS platforms and any troubleshooting you've done. This will show that you're not just familiar with the theory but also have practical skills.
✨Showcase Your Collaborative Spirit
Since this role involves working closely with various teams, prepare examples of how you've successfully collaborated in the past. Think about specific projects where you integrated data with other disciplines, like structural biology or medicinal chemistry, and be ready to share those stories.
✨Communicate Clearly and Confidently
Practice explaining complex scientific concepts in a way that's easy to understand. You might need to present your findings or discuss your methods, so being able to communicate effectively with different audiences is key. Consider doing mock interviews with friends or colleagues to refine your delivery.
✨Demonstrate Your Problem-Solving Skills
Prepare to discuss specific challenges you've faced in your research and how you overcame them. Highlight your scientific problem-solving abilities and your understanding of data analysis principles, especially in relation to small molecule MS analysis. This will help illustrate your critical thinking skills and adaptability.