Head of Manufacturing Operations
Overview
We are seeking an experienced leader to oversee day-to-day operations at a UK-based pharmaceutical manufacturing facility specialising in the production of unlicensed medicines (“specials”). The role requires a balance of strategic leadership and hands-on operational oversight to ensure regulatory compliance, efficiency, and the delivery of high-quality products that put patient safety first.
Key Responsibilities
- Ensure compliance and governance by maintaining SOPs, embedding GMP standards and data integrity practices, and sustaining a trained, competent workforce.
- Oversee production planning by translating forecasts and patient-specific orders into achievable schedules, while managing material flow, segregation, and availability.
- Manage batch execution and documentation to ensure the use of approved records, accurate reconciliation, and timely resolution of queries.
- Maintain facilities and equipment in partnership with Engineering, ensuring calibration, qualification, and effective contamination control measures are in place.
- Lead validation and change initiatives, supporting process validation, technology transfers, and process improvements under change control.
- Drive investigations and improvements by leading root cause analysis, implementing effective CAPAs, and reducing inefficiencies through Lean/Six Sigma methodologies.
- Foster people and culture development by building a high-performing team, setting objectives, coaching staff, and promoting a safety- and quality-first mindset.
- Act as subject matter expert during audits, ensuring the site remains in a constant state of inspection readiness.
- Support GDP and controlled drug management where applicable, ensuring full compliance with licence conditions in collaboration with the Responsible Person.
- Work closely with Quality leadership to jointly oversee compliance, approve controlled documentation, manage supplier performance, review batch records, and maintain readiness for internal and external audits.
Experience and Qualifications
- Degree in Pharmacy, Pharmaceutical Sciences, Chemistry, Microbiology, Engineering, or a related scientific discipline.
- Extensive experience (7+ years) in GMP-regulated pharmaceutical manufacturing, with a strong track record in operational leadership (3-5 years).
- Proven success in achieving production targets while delivering improvements in yield, right-first-time metrics, and deviation rates.
- Demonstrated expertise in investigations, CAPA, change control, and working with cross-functional teams.
- Previous exposure to small-batch or patient-specific manufacturing is highly desirable.
Personal Profile
- Decisive and calm under pressure, with the judgement to prioritise patient safety and compliance above all else.
- Highly detail-oriented, with deep knowledge of GMP and production controls.
- Skilled in planning, resource management, and operational delivery.
- Analytical, data-driven, and confident applying structured problem-solving tools.
- A clear and persuasive communicator, able to connect with both shopfloor teams and senior stakeholders.
- A role model for integrity, GMP behaviours, and a culture of continuous improvement.
Seniority level
- Director
Employment type
- Full-time
Job function
- Production and Management
- Industries: Pharmaceutical Manufacturing and Biotechnology Research
Note: This description focuses on the responsibilities and qualifications for the Head of Manufacturing Operations role at a UK-based pharmaceutical facility.
Head of Production in Birmingham employer: Next Phase Recruitment
As a Partner Implementation Manager at our innovative scientific SaaS company, you'll thrive in a dynamic work culture that prioritises collaboration and excellence. Located in vibrant London or New York City, we offer competitive benefits, continuous professional development opportunities, and the chance to work with leading organisations in cutting-edge industries. Join us to make a meaningful impact while advancing your career in a supportive environment that values your expertise and contributions.
StudySmarter Expert Advice🤫
We think this is how you could land Head of Production in Birmingham
✨Join Local Manufacturing Groups
Getting involved in local manufacturing groups or associations can seriously boost your visibility. These groups often have insider info on job openings and networking events, plus they help you connect with like-minded folks in the industry. Check out what's happening in your area!
✨Show Off Your Skills in Practical Spaces
Consider participating in workshops or open days at manufacturing companies. It's a great way to show off your hands-on skills in a real-world environment and can sometimes lead to job offers right on the spot. Keep an eye on announcements from local manufacturers for these opportunities!
✨Leverage the Power of Internships
While you're looking for full-time positions, don't underestimate the power of internships! Even if you don't see a direct role, securing an internship at a company can open doors to future jobs. Many manufacturing firms prefer to hire from their intern pool, so it's definitely worth considering.
✨Apply Directly Through Company Websites
When you find a role at a company you love, like Next Phase Recruitment, apply directly on their website. This way, you’re more likely to be noticed by the hiring team. Plus, showing that you took the time to seek out their application process highlights your genuine interest in the firm!
Some tips for your application 🫡
Showcase Your Technical Skills:In the manufacturing-production sector, it's crucial to highlight your technical skills and experience. Make sure your CV features any relevant qualifications, such as certifications in machinery operation or production management, and don’t forget about any specific systems or software you’re familiar with. This can really set you apart!
Emphasise Teamwork and Communication:Working in manufacturing often means being part of a larger team. Highlight your experience in collaborative projects or environments where communication was key. Maybe you have experience with lean manufacturing principles? Talk about how you worked with your team to improve productivity and maintain quality.
Tailor Your Cover Letter to the Company:Don’t just recycle an old cover letter! Take the time to tailor your cover letter to Next Phase Recruitment specifically. Mention what excites you about their production processes or products, and how your previous experiences can contribute to their goals. We want to see your enthusiasm for the role!
Use Concrete Examples of Your Achievements:When detailing your work experience, include measurable achievements that can demonstrate your impact. Whether it’s improving efficiency by a certain percentage or successfully leading a project, these specifics can make a huge difference. Numbers speak volumes in the manufacturing world!
How to prepare for a job interview at Next Phase Recruitment
✨Know Your Manufacturing Processes
Before you walk into the interview with Next Phase Recruitment, brush up on the specific manufacturing processes relevant to the role. Understanding lean manufacturing principles or quality control techniques could give you a solid edge to discuss how you’d fit into their operations.
✨Technical Questions Are Key
Be prepared for technical questions around machinery, production scheduling, or materials handling. Make sure you can confidently explain how you've dealt with these in past experiences or internships. Knowing industry-specific software could also be a big plus!
✨Showcase Your Problem-Solving Skills
Manufacturing environments often focus on continuous improvement. Be ready to discuss specific instances where you’ve solved a production issue or implemented a process improvement. It’s all about demonstrating your analytical thinking and hands-on approach.
✨Align Your Values with Quality and Safety
In a full-time role, companies like Next Phase Recruitment value commitment to quality and safety. Be prepared to discuss how you prioritise these factors in your work. It’s about showing that you’re not just looking for a job, but that you genuinely care about contributing positively to their production environment.
