At a Glance
- Tasks: Develop and validate analytical methods for cutting-edge lipid and nanoparticle components.
- Company: Join NeoVac, a pioneering biotech company revolutionising mRNA vaccine delivery.
- Benefits: Competitive salary, flexible working hours, and opportunities for professional growth.
- Why this job: Make a real difference in global health by tackling serious diseases with innovative science.
- Qualifications: Master's degree in relevant field and 3+ years of HPLC experience required.
- Other info: Dynamic start-up environment with a focus on collaboration and innovation.
The predicted salary is between 36000 - 60000 £ per year.
NeoVac is building a new ground-breaking LNP platform to deliver better mRNA vaccines and treatments for various diseases. At NeoVac, we envision a world where mRNA vaccines and treatments are available to everyone and everywhere. We are applying science and technology to address some of the most serious conditions affecting humanity, including increasing antibiotic resistance, cancer, and viral illnesses. We aspire to be the leading life science company in this field.
RESPONSIBILITIES & DUTIES
- As an Analytical Scientist, you will be responsible for the development, optimisation, and validation of analytical methods to characterise lipids, PEG-polymers, nanoparticle components, process intermediates, and final drug substances.
- You will work closely with formulation chemistry, RNA teams, and manufacturing partners to support drug development from discovery through early GMP stages.
- This role requires strong laboratory autonomy, problem-solving capabilities, and a passion for high-quality data.
- Develop, optimise, and validate analytical methods for lipids, polymers, and nanoparticle components using HPLC-CAD, HPLC-UV, and LC-MS.
- Perform structural and compositional profiling of PEG-lipids, ionisable lipids, and excipients.
- Execute method validation according to ICH Q2 and support transition into cGMP workflows.
- Conduct routine and non-routine analyses: assay, related impurities, stability studies and Endotoxin analysis.
- Independently troubleshoot analytical methods and instruments.
- Interpret data, prepare reports, and present results to cross-functional teams.
- Support external CROs, CDMOs, and GMP partners as needed.
- Contribute to building analytical capability in a growing biotech environment, including SOPs, workflows, and instrument best practices.
REQUIRED QUALIFICATIONS & EXPERIENCE
- Master's degree (MSc or higher) in Chemistry, Analytical Chemistry, Pharmaceutical Sciences or related field.
- 3+ years handsāon experience with HPLC in industry (pharma/biotech preferred).
- Demonstrated proficiency with HPLC-CAD (strongly preferred).
- Handsāon experience with LCāMS for lipid or polymer analysis.
- Proven track record of method development (minimum 3ā5 methods).
- Experience with cGMP method validation (at least 2 methods independently validated).
- Prior experience working in a GMP or cGMP analytical lab.
- Strong practical skills, autonomy, and troubleshooting abilities.
- Excellent documentation practices; familiarity with ICH Q2, Q14, and relevant regulatory guidelines.
- Ability to thrive in a fastāpaced, collaborative startāup environment.
DESIRABLE SKILLS
- Experience with lipid nanoparticles (LNPs), PEGālipids, polymers, or novel excipients.
- Experience with charged aerosol detection optimisation.
- Knowledge of DSC, Capillary Electrophoresis (CE), and Bacterial Endotoxin analysis.
- Familiarity with raw material qualification and release testing.
Application closer to this position may be considered but not guaranteed. Duties, responsibilities, and activities may change, or new ones may be assigned at any time with or without notice, as per everāchanging business needs.
Analytical Scientist (Biotechnology/LNP & Lipid Analytics) in Abingdon employer: NeoVac
Contact Detail:
NeoVac Recruiting Team
StudySmarter Expert Advice š¤«
We think this is how you could land Analytical Scientist (Biotechnology/LNP & Lipid Analytics) in Abingdon
āØTip Number 1
Network like a pro! Reach out to professionals in the biotech field, especially those working with LNPs and lipid analytics. Attend industry events or webinars to make connections that could lead to job opportunities.
āØTip Number 2
Show off your skills! Prepare a portfolio showcasing your analytical methods and any successful projects you've worked on. This will help you stand out during interviews and demonstrate your hands-on experience.
āØTip Number 3
Practice makes perfect! Conduct mock interviews with friends or mentors to refine your responses, especially around your experience with HPLC and method validation. The more comfortable you are, the better you'll perform.
āØTip Number 4
Apply through our website! We at StudySmarter encourage you to submit your application directly on our platform. Itās a great way to ensure your application gets the attention it deserves!
We think you need these skills to ace Analytical Scientist (Biotechnology/LNP & Lipid Analytics) in Abingdon
Some tips for your application š«”
Tailor Your CV: Make sure your CV is tailored to the Analytical Scientist role. Highlight your experience with HPLC, LC-MS, and method validation, as these are key for us at NeoVac. Use specific examples that showcase your skills in lipid and polymer analysis.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about biotechnology and how your background aligns with our mission at NeoVac. Share your enthusiasm for developing mRNA vaccines and treatments, and donāt forget to mention any relevant projects you've worked on!
Showcase Your Problem-Solving Skills: In your application, be sure to highlight instances where you've independently troubleshot analytical methods or instruments. We love candidates who can think on their feet and tackle challenges head-on, so share those stories!
Apply Through Our Website: We encourage you to apply directly through our website. Itās the best way for us to receive your application and ensures youāre considered for the role. Plus, it shows us youāre proactive and keen to join our team!
How to prepare for a job interview at NeoVac
āØKnow Your Analytical Methods
Make sure you brush up on your knowledge of HPLC, LC-MS, and method validation. Be ready to discuss specific methods you've developed or optimised in the past, especially those relevant to lipids and polymers. This shows you're not just familiar with the theory but have practical experience too.
āØShow Your Problem-Solving Skills
Prepare examples of how you've independently troubleshot analytical methods or instruments in previous roles. NeoVac values strong problem-solving capabilities, so demonstrating your ability to tackle challenges head-on will set you apart from other candidates.
āØFamiliarise Yourself with cGMP Practices
Since this role involves working in a cGMP environment, be prepared to discuss your experience with cGMP method validation and any relevant regulatory guidelines like ICH Q2. Showing that you understand these practices will reassure them that you can hit the ground running.
āØEmphasise Collaboration
NeoVac is a collaborative start-up, so highlight your experience working with cross-functional teams. Share specific instances where youāve successfully collaborated with formulation chemistry or manufacturing partners, as this will demonstrate your ability to thrive in their fast-paced environment.