Senior Clinical Development Scientist

Work location: Remote, based in US or Hybrid, based in London

Myricx is a pioneering global biotech company advancing innovative antibody-drug conjugates (ADCs) that deliver inhibitors of N-myristoyltransferase (NMT)

We are a small but rapidly growing team, with a vision to advance a pipeline of ADCs based on our novel NMTi payload chemistry platform. This novel mechanism-of-action holds significant promise for treating cancer and other diseases

As leaders in NMT biology and pharmacology, Myricx successfully raised £90 million ($114 million) in Series A financing in 2024 to advance our pipeline of ADC therapeutics. We are recruiting for a Senior Clinical Development Scientist who will be responsible for the scientific oversight and execution of early-phase oncology clinical trial(s).

Role Overvew;

The Clinical Development Scientist will collaborate closely with cross-functional teams, to drive the development of novel oncology therapies. The successful candidate will have strong experience in clinical trial design, protocol development, scientific data interpretation, and CRO management, and will also be responsible for medical monitoring duties. This role requires a highly motivated, detail-oriented professional with a strong scientific background

Key Responsibilities;

Clinical Trial Support:

• Support the clinical development plan, including the planning and execution of clinical trials.
• Collaborate with clinical teams, CROs, and investigators to ensure scientific rigour and effective trial conduct.
• Author and revise essential clinical trial documents, including protocols, informed consent forms (ICFs), patient information sheets (PIS), trial-specific guidelines, and clinical study reports.
• Ensure that all documents are compliant with regulatory requirements, ethical standards, and company SOPs.

CRO Management:

• Serve as the point of contact for CROs, ensuring high-quality execution of clinical trials
• Participate in CRO selection and provide input during the vendor evaluation process.
• Participate in the management of scientific aspects of the CRO relationship including ensuring appropriate personnel and training.

Data Analysis and Interpretation:

• Analyse/Visualise emerging clinical trial data using current software tools.
• Interpret/present scientific data from ongoing clinical trials to inform decision-making and identify potential issues.
• Summarise data and present to internal and external stakeholders, including data safety monitoring boards (DSMBs).
• Identify trends and address any data issues in emerging clinical trial databases.

Medical Monitoring and Safety Oversight:

• Contribute to the medical monitoring of clinical trials, including review of safety data.
• Collaborate with the project medical monitor and safety teams to identify and evaluate any potential safety signals.
• Participate in safety data reviews and contribute to the management of serious adverse events (SAEs).

Scientific Expertise:

• Maintain knowledge of the current literature in relevant therapeutic areas.

Requirements:

• BSc or MSc in Life Sciences (e.g. biology, pharmacology, or related studies). Demonstrated considerable experience in early-phase development, including executing Phase 1/2 oncology clinical trials
• Experience with regulatory submissions (e.g. IND, BLA, MAA)
• Excellent scientific writing and proven ability to lead the development of clinical documents including trial protocols, ICFs, PIS, and other.
• Strong experience working with CROs
• Experience managing or overseeing clinical trials in international regions
• Knowledge of GCP, ICH guidelines.
• Experience with EDC systems, eCRFs and other clinical trial technologies.

Desirable skills:

• Experience with multiple cancer indications, and knowledge of cancer biology.

What’s in it for you? Why work at Myricx

We are a small but rapidly growing team, with a vision to advance a pipeline of ADCs based on our novel NMT inhibitor (NMTi) payload chemistry platform to address serious unmet needs in oncology. As an early joiner, you will have a unique opportunity to help shape our trajectory and make real impact from day one.

Myricx Bio s an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.