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- Tasks: Lead innovative projects in advanced cell models for drug safety and development.
- Company: Join AstraZeneca, a global leader in life-changing medicines and an inclusive employer.
- Benefits: Enjoy flexible working options and a collaborative environment that values diversity.
- Why this job: Make a real impact on global health by advancing cutting-edge science and technology.
- Qualifications: PhD in relevant fields with strong experience in drug discovery and advanced cell models.
- Other info: Work from various locations including Cambridge, Gothenburg, Boston, or Gaithersburg.
The predicted salary is between 60000 - 84000 £ per year.
DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES
Join to apply for the DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES role at myGwork – LGBTQ+ Business Community
DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES
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This job is with AstraZeneca, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.
Title: Director- Advance Cell Model Innovation- Safety Sciences – permanent
Location: Cambridge UK, Gothenburg SE, Boston MA, Gaithersburg MD
Salary: Competitive
At AstraZeneca, we push the boundaries of science to deliver life-changing medicines. Our global Safety Sciences organisation delivers innovative non-clinical safety science and toxicology expertise to enable the discovery, development and registration of novel medicines across drug modalities and therapeutic areas.
As a science-driven business, we continuously strive to innovate to enhance our scientific capabilities and accelerate the speed at which we bring medicines forward.
Advanced Cell Models (ACM), such as organoids and Microphysiological Systems (MPS), are New Approach Methods (NAMs) being used for safety assessment and to study disease biology. We are playing a leading role in the field to apply ACM to drug discovery and development, in particular to predict and optimise therapeutic index for novel candidate drugs.
To enhance our ACM strategy, we are looking to recruit a Director – Advanced Cell Model Innovation, Safety Sciences.
The role can be based at any of our R&D sites in Cambridge (UK), Gothenburg (Sweden), Boston MA (US) or Gaithersburg MD (DC metro area, US), it is part of the Advanced Cell Models Team and reports to the Senior Director, Head of Advanced Cell Models, Safety Sciences.
Accountability
Lead a forward-looking Advanced Cell Model (ACM) science and technology vision exploring new technologies, platforms and in-line biomarker detection systems, and overseeing their implementation to humanise prediction of safety and therapeutic index and enhance productivity.
Develop and own the Advanced Cell Model strategic plan aligned with AZ 3Rs and work with internal stakeholders and external consortia and health authorities to qualify, validate and gain acceptance of NAMs in accordance with, for example, FDA and EMA Roadmaps.
Responsible for scouting external science and providers, and provide expert input into decisions to explore, implement, and invest in new methodology/technology.
Impact on R&D globally by leading cross-enterprise partnerships with innovation leaders to facilitate the sharing of ideas to optimise the application of ACM aligned to the 3Rs, providing expert technical direction and problem solving.
Work with Clinical Pharmacology and Safety Sciences and R&D IT data science experts to ensure data are FAIR, supporting workflows for biological data capture, insights, systems modelling and application of AI/ML for the development of \”digital twins\”, and align internal data standards with external consortia (e.g. ISO), white papers and health authority requirements.
Requirements
Strong academic background with PhD in a relevant field (Cell Biology, Engineering, Pharmacology, Toxicology or related discipline), with high quality publications.
Excellent understanding of ACM and NAMs (including organoids, MPS, in silico modelling), 3Rs and regulatory requirements for drug development.
A proven understanding of drug discovery and development, with a strong track record of independent research in industry, biotech, or academic setting.
Track record of scientific innovation, leading development and application of cutting-edge, novel science.
A collaborative, team-oriented approach, able to solve problems in a goal-focused fashion with capacity to coordinate tasks across multiple projects.
Excellent influencing, communication and presentation skills, ability to work across scientific disciplines and bridge organizational boundaries.
Level of the role (Director / Associate Director) will be based on experience, understanding of drug discovery and development, and track record of successful development and application of cutting-edge, novel ACM/NAMs science.
When we put unexpected teams in the same room, we fuel ambitious thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That\’s why we work, on average, a minimum of three days per week from the office. But that doesn\’t mean we\’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Join the team unlocking the power of what science can do. We are working towards treating, preventing, modifying and even curing some of the world\’s most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. Our combination of curiosity and courage drives us to explore new possibilities without fear of failure. We celebrate our successes and learn from our failures along the way. Our inclusive environment allows us to work seamlessly as one team, using diverse global knowledge to create the greatest impact on disease.
If your passion is science and you want to be part of a team that makes a bigger impact on patients\’ lives, then there\’s no better place to be. Apply now!
what is next?
Are you ready to make a difference? Apply today and join us in our mission to improve global public health!
We welcome your applications not later than 27th July 2025.
Where can I find out more?
Follow AstraZeneca on LinkedIn AstraZeneca on Facebook AstraZeneca on Instagram you ready to make a difference? Apply today and join us in our mission to improve global public health!
Salary : Negotiable
Seniority level
-
Seniority level
Director
Employment type
-
Employment type
Full-time
Job function
-
Job function
General Business, Management, and Business Development
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Industries
Biotechnology
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DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES employer: myGwork - LGBTQ+ Business Community
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StudySmarter Expert Advice 🤫
We think this is how you could land DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES
✨Tip Number 1
Network with professionals in the field of Advanced Cell Models and Safety Sciences. Attend relevant conferences, webinars, or workshops to connect with industry leaders and gain insights into the latest trends and technologies.
✨Tip Number 2
Engage with AstraZeneca's online presence. Follow them on LinkedIn and other social media platforms to stay updated on their projects and initiatives, which can help you tailor your discussions during interviews.
✨Tip Number 3
Prepare to discuss your experience with Advanced Cell Models and New Approach Methods in detail. Be ready to share specific examples of how you've contributed to innovative projects or research in these areas.
✨Tip Number 4
Familiarise yourself with the regulatory landscape surrounding drug development, particularly the FDA and EMA guidelines. Understanding these frameworks will demonstrate your readiness to navigate the complexities of the role.
We think you need these skills to ace DIRECTOR ADVANCED CELL MODEL INNOVATION, SAFETY SCIENCES
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in advanced cell models, safety sciences, and drug development. Use specific examples that demonstrate your expertise in these areas.
Craft a Compelling Cover Letter: Your cover letter should reflect your passion for science and innovation. Discuss how your background aligns with AstraZeneca's mission and the specific requirements of the Director role.
Highlight Collaborative Experience: Given the emphasis on teamwork in the job description, include examples of successful collaborations across disciplines. Showcase your ability to lead and influence within a team setting.
Showcase Scientific Innovation: Detail any previous work where you led scientific innovation or developed novel methodologies. This will demonstrate your capability to contribute to AstraZeneca's goals in advanced cell model innovation.
How to prepare for a job interview at myGwork - LGBTQ+ Business Community
✨Showcase Your Academic Background
Make sure to highlight your PhD and any relevant publications during the interview. Discuss how your academic journey has prepared you for the role, especially in relation to Advanced Cell Models and New Approach Methods.
✨Demonstrate Your Understanding of ACM and NAMs
Be prepared to discuss your knowledge of Advanced Cell Models, organoids, and Microphysiological Systems. Illustrate how these concepts apply to drug discovery and development, and share any innovative ideas you have in this area.
✨Emphasise Collaboration Skills
Since the role involves working across various teams, be ready to provide examples of how you've successfully collaborated in the past. Highlight your ability to bridge gaps between scientific disciplines and coordinate tasks across multiple projects.
✨Prepare for Technical Questions
Expect to face technical questions related to drug discovery, safety sciences, and regulatory requirements. Brush up on the latest trends and challenges in these areas, and be ready to discuss how you would tackle them in your role.
