At a Glance
- Tasks: Conduct groundbreaking research on neurodegeneration and develop innovative methods for alpha-synuclein filament formation.
- Company: Join the prestigious MRC Laboratory of Molecular Biology in Cambridge, UK.
- Benefits: Enjoy a competitive salary, generous holiday entitlement, and excellent training opportunities.
- Other info: Embrace a diverse and inclusive workplace with strong support for career development.
- Why this job: Make a real impact in neurobiology and collaborate with leading scientists in the field.
- Qualifications: PhD in a relevant subject or nearing completion, with experience in cryo-EM or amyloid formation.
The predicted salary is between 42694 - 42694 € per year.
Salary £42,694 per annum; Fixed term, 3 years; MRC Laboratory of Molecular Biology, Cambridge, UK.
Overview
To work in the group of Dr Michel Goedert from the Neurobiology Division of the MRC Laboratory of Molecular Biology (LMB), as part of a programme aimed at understanding Molecular Mechanisms of Neurodegeneration. Specifically, to undertake research to develop methods for forming alpha‑synuclein filaments with the same structures as those from human brain. This work will be done in close collaboration with the group of Dr Sjors Scheres from the Structural Studies Division of the LMB.
Responsibilities
- Develop methods for forming alpha‑synuclein filaments that mimic the structures observed in human brains.
- Use electron cryo‑microscopy (cryo‑EM) to determine filament folds and investigate disease‑specific structures.
- Carry out immunoprecipitation and mass spectrometry to identify the chemical identity of cofactors, in collaboration with Professor P. Barran, University of Manchester.
- Develop and refine techniques for producing alpha‑synuclein folds in vitro, in cells and in animal models, and analyse these folds using cryo‑EM.
- Collaborate closely with structural biology teams and contribute to interdisciplinary research efforts.
Qualifications
- A PhD in a relevant subject or due to complete a PhD within 6 months is necessary.
- Experience in generating experimental models of amyloid formation and/or cryo‑EM or cryo‑ET.
- Good communication skills and the ability to work effectively both independently and in a group.
Benefits
- Defined benefit pension scheme.
- Holiday entitlement of 40.5 days per annum (including bank holidays and privilege days).
- Generous employee discount scheme.
- Training and development opportunities, including support toward role‑related qualifications.
Equality, Diversity and Inclusion
We actively support equality, diversity and inclusion in all our activities, processes and culture. We encourage applications from all sections of society. The LMB particularly welcomes women, minority ethnic and disabled candidates to apply for this vacancy as they are currently under‑represented. We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require.
Closing date: 31 May 2026. Final appointments will be subject to a pre‑employment screening. This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs (visa and health surcharge) can be reclaimed from UKRI after taking up the post (terms and conditions apply).
Postdoctoral Scientist | Neurobiology | Dr Michel Goedert | LMB 2253 employer: MRC Laboratory of Molecular Biology (LMB)
The MRC Laboratory of Molecular Biology (LMB) in Cambridge is an exceptional employer, offering a vibrant work culture that fosters collaboration and innovation in neurobiology research. With generous benefits including a defined benefit pension scheme, 40.5 days of holiday, and extensive training opportunities, the LMB is committed to supporting employee growth and well-being. The inclusive environment actively promotes diversity, making it an ideal place for talented individuals from all backgrounds to contribute to groundbreaking scientific advancements.
Contact Detail:
MRC Laboratory of Molecular Biology (LMB) Recruiting Team
StudySmarter Expert Advice🤫
We think this is how you could land Postdoctoral Scientist | Neurobiology | Dr Michel Goedert | LMB 2253
✨Network Like a Pro
Get out there and connect with folks in your field! Attend conferences, seminars, or even local meet-ups. We all know that sometimes it’s not just what you know, but who you know that can help land that dream job.
✨Show Off Your Skills
Don’t just sit back and wait for opportunities to come to you. Create a portfolio or a personal website showcasing your research and projects. We want to see what you can do, so make it easy for potential employers to find your work!
✨Ace the Interview
When you get that interview, prepare like it’s the final exam! Research the lab and the people you’ll be working with. We suggest practising common interview questions and having a few of your own ready to show your interest and enthusiasm.
✨Apply Through Our Website
We highly recommend applying directly through our website. It’s the best way to ensure your application gets seen by the right people. Plus, you’ll find all the info you need about the role and our team!
We think you need these skills to ace Postdoctoral Scientist | Neurobiology | Dr Michel Goedert | LMB 2253
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to highlight your relevant experience in neurobiology and any specific techniques like cryo-EM. We want to see how your background aligns with the role, so don’t hold back on showcasing your skills!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you’re passionate about neurodegeneration research and how you can contribute to Dr Goedert's team. Keep it engaging and personal – we love to see your enthusiasm!
Highlight Collaboration Experience:Since this role involves working closely with other teams, make sure to mention any past collaborative projects. We value good communication skills and teamwork, so share examples of how you've successfully worked with others in your field.
Apply Through Our Website:Don’t forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it’s super easy – just follow the prompts and you’ll be set!
How to prepare for a job interview at MRC Laboratory of Molecular Biology (LMB)
✨Know Your Research Inside Out
Make sure you’re well-versed in the latest findings related to alpha-synuclein and neurodegeneration. Familiarise yourself with Dr Goedert's work and any recent publications from the LMB. This will not only show your genuine interest but also help you engage in meaningful discussions during the interview.
✨Showcase Your Technical Skills
Be prepared to discuss your experience with cryo-EM, immunoprecipitation, and mass spectrometry. Bring examples of past projects where you’ve successfully used these techniques. If possible, highlight any innovative methods you developed or challenges you overcame in your research.
✨Emphasise Collaboration
Since this role involves working closely with other teams, be ready to share examples of how you’ve collaborated in the past. Discuss how you communicate effectively within a team and how you handle differing opinions or conflicts. This will demonstrate your ability to thrive in an interdisciplinary environment.
✨Prepare Thoughtful Questions
At the end of the interview, you’ll likely have the chance to ask questions. Prepare insightful queries about the lab’s current projects, future directions, or the collaborative efforts with Dr Scheres’ group. This shows your enthusiasm for the role and helps you assess if it’s the right fit for you.
