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- Tasks: Lead a team to engineer innovative protein therapeutics for unmet medical needs.
- Company: Join Gilead Sciences, a leader in biopharmaceutical innovation.
- Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
- Why this job: Make a real impact in drug development and improve patient lives.
- Qualifications: Ph.D. in relevant field with significant industry experience required.
- Other info: Dynamic, fast-paced environment with strong collaboration across teams.
The predicted salary is between 54000 - 84000 £ per year.
The Protein Therapeutics team in Oxford UK is seeking an experienced and innovative leader to contribute to the engineering of large molecule drug candidates including antibodies, multispecifics or immune cell engagers, and immunocytokines, as well as to the development of new, cutting-edge capabilities at the site. The successful candidate will lead a Biologics Engineering team and oversee biologic projects primarily focused on Inflammation.
The core responsibilities include biologics design and optimization to enable discovery projects from conceptualization to drug candidate nomination, and advancement of engineering technologies to enable large molecule drug development. Effective collaboration across multiple functions, including those located in Foster City, CA is a crucial attribute of this role.
Essential Duties and Job Functions- Lead a team of protein engineers to discover and optimize innovative protein therapeutics to address unmet medical needs through differentiated mechanisms of action.
- Represent Protein Therapeutics on interdisciplinary project teams and deliver large molecule drug candidates matching the Target Product Profile specifications.
- Drive rapid optimization of novel antibody and protein therapeutics through iterative design, build, test, and learn cycles.
- Independently carry out lead sequence and format optimizations utilizing rational and in silico design approaches.
- Communicate transparently and timely to key stakeholders to build strong partnership and collaboration experiences.
- Supervise and mentor scientists to support their continued career development.
- Thrive in a fast paced, data-driven, and scientifically rigorous environment.
- Maintain compliance with company policies and record keeping.
Basic qualifications: Ph.D. in molecular and cell biology, structural biology, or equivalent degrees in a highly related discipline.
Preferred qualifications: Ph.D. and postdoctoral trainings plus significant industry experience.
- Broad understanding of industry and competitive landscape.
- Significant experience in an industry setting and a record of accomplishments reflected by presentations, high impact publications, or issued patents with demonstrable protein engineering expertise.
- Extensive experience advancing protein therapeutics from discovery to development and stays abreast with emerging protein engineering platforms and technologies.
- Expertise in structure-based protein engineering and design of multispecifics, immunocytokines, Fc engineering, and fusion proteins.
- Skilled practitioner in antibody engineering, including humanization, sequence liability remediation, and/or biophysical property improvement.
- Project leadership and core team membership experience in pharmaceutical industry R&D environment across multiple therapeutic areas, with a deep understanding of lead identification and optimization through preclinical development of therapeutic candidates.
- Proficient in various molecular biology and recombinant protein techniques, as well as experience (preferred) or familiarity with mammalian cell culture, protein expression, purification, and characterization; familiarity in antibody discovery platforms is a plus.
- Experience with computational design tools preferred (e.g. MOE) and biologic informatics system (e.g., Genedata Biologics and Screener).
- Team leader and player who is articulate and precise, with emotional intelligence, professional maturity and strong leadership and problem-solving skills.
Director – Protein Therapeutics employer: MiroBio Ltd
Contact Detail:
MiroBio Ltd Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Director – Protein Therapeutics
✨Tip Number 1
Network like a pro! Reach out to your connections in the industry, especially those who might know someone at Gilead. A friendly chat can open doors that a CV just can't.
✨Tip Number 2
Prepare for interviews by diving deep into the latest trends in protein therapeutics. Show us you’re not just a candidate, but a thought leader who’s ready to drive innovation in the field.
✨Tip Number 3
Practice your storytelling skills! Be ready to share your journey and how your experiences align with the role. We love hearing about your successes and how you’ve tackled challenges in your career.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets the attention it deserves. Plus, we’re always on the lookout for passionate candidates like you!
We think you need these skills to ace Director – Protein Therapeutics
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Director – Protein Therapeutics. Highlight your experience in protein engineering and any relevant projects you've led. We want to see how your background aligns with our needs!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about protein therapeutics and how your leadership style can benefit our team. Let us know what makes you the perfect fit for this role.
Showcase Your Achievements: Don’t just list your responsibilities; showcase your achievements! Include specific examples of how you've advanced protein therapeutics or led successful projects. We love seeing quantifiable results that demonstrate your impact.
Apply Through Our Website: We encourage you to apply through our website for the best chance of being noticed. It’s straightforward, and we’ll be able to track your application easily. Plus, it shows you’re keen on joining our team!
How to prepare for a job interview at MiroBio Ltd
✨Know Your Science
Make sure you brush up on the latest advancements in protein therapeutics and biologics engineering. Be ready to discuss your experience with antibody design, optimization, and any relevant technologies you've worked with. This will show that you're not just a leader but also a knowledgeable expert in the field.
✨Showcase Your Leadership Skills
Prepare examples of how you've successfully led teams in the past, especially in fast-paced environments. Highlight your mentoring experiences and how you've fostered collaboration across different functions. This is crucial for a role that requires effective teamwork and communication.
✨Be Ready for Technical Questions
Expect in-depth questions about your technical expertise, particularly around structure-based protein engineering and the specific techniques mentioned in the job description. Practise articulating your thought process in problem-solving scenarios, as this will demonstrate your analytical skills.
✨Understand the Company Culture
Research Gilead Sciences and their approach to innovation and collaboration. Be prepared to discuss how your values align with theirs and how you can contribute to their mission. Showing that you understand their culture will help you stand out as a candidate who fits well within their team.
